Difelikefalin: all 28 studies that test it

Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• Difelikefalin for Itching in Hemodialysis Patients With Chronic Kidney DiseaseNot yet recruitingNCT07526324Not applicable
• Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe PruritusRecruitingNCT06593392Phase 2
• Pharmacokinetics of Intravenous Difelikefalin in Chinese Adult Subjects on HaemodialysisCompletedNCT05885763Phase 1Results posted
• Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe PruritusCompletedNCT05885737Phase 3Results posted
• A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.CompletedNCT04711603Phase 3Results posted
• CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe PruritusCompletedNCT03998163Phase 3Results posted
• A Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.CompletedNCT03802617Phase 2Results posted
• CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe PruritusCompletedNCT03636269Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe PruritusCompletedNCT03617536Phase 2Results posted
• A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)CompletedNCT03422653Phase 3Results posted
• Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe PruritusCompletedNCT03281538Phase 3Results posted
• A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or KneeCompletedNCT02944448Phase 2Results posted
• Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe PruritusCompletedNCT02858726Phase 2/3Results posted
• A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy SurgeryCompletedNCT01789476Phase 2Results posted
• Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy SurgeryCompletedNCT01361568Phase 2Results posted
• Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy SurgeryCompletedNCT00877799Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia ParestheticaTerminatedNCT05978063Phase 2/3
• CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis PatientsCompletedNCT05533008Phase 1
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic DermatitisTerminatedNCT05387707Phase 3
• CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe PruritusTerminatedNCT05356403Phase 3
• A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe PruritusTerminatedNCT05342623Phase 3
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)CompletedNCT04706975Phase 2
• Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy SubjectsCompletedNCT04019574Phase 1
• Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic DermatitisCompletedNCT04018027Phase 2
• Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe PruritusTerminatedNCT03995212Phase 2
• Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy SubjectsCompletedNCT03947970Phase 1
• A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal SurgeryCompletedNCT02542384Phase 2/3
• Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic PruritusCompletedNCT02229929Phase 2

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