An interventional study of Hyoscine N Butylbromide and Normal Saline 0.9% in Prolonged Labor, sponsored by Cairo University. Completed at 1 site in Egypt. Open to female participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2021-10-07.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
Women will be admitted when active phase of labour starts defined as the presence of at least three regular uterine contractions over 10 minutes with cervical dilatation four centimeters with cervical effacement not less than 50% and no progress of labor for 2 hours or more.
Amniotomy was done in those with intact membrane and continuous electronic fetal monitoring was done. Women with prolonged labor after these measures were randomly divided using automated web-based randomization system into 2 equal groups. Group I included 50 women received 40mg HBB (Buscopan, Memphis Co, Giza, Egypt) intravenous bolus injection. Group II included 50 women received 2 ml of normal saline. The obstetrician, participants and outcome assessor were all blinded to the group assignment. Labor will be monitored by Vaginal examination every two hours. The duration of the first stage was calculated from the time of cervical dilatation of three to four centimeters in active labor until a fully dilated cervix was observed.
Women will be admitted when active phase of labour starts defined as the presence of at least three regular uterine contractions over 10 minutes with cervical dilatation four centimeters with cervical effacement not less than 50% and no progress of labor for 2 hours or more.
Amniotomy was done in those with intact membrane and continuous electronic fetal monitoring was done. Women with prolonged labor after these measures were randomly divided using automated web-based randomization system into 2 equal groups. Group I included 50 women received 40mg HBB (Buscopan, Memphis Co, Giza, Egypt) intravenous bolus injection. Group II included 50 women received 2 ml of normal saline. The obstetrician, participants and outcome assessor were all blinded to the group assignment. Labor will be monitored by Vaginal examination every two hours. The duration of the first stage was calculated from the time of cervical dilatation of three to four centimeters in active labor until a fully dilated cervix was observed.
Nulliparous women.
Exclusion Criteria:
7. Group A will receive injection Hyoscine butyl bromide 40 mg single intravenous dose
Drug: Hyoscine N Butylbromide
Group B, will receive 2 ml of normal saline single intravenous dose
Drug: Normal Saline 0.9%
7. Group A will receive injection Hyoscine butyl bromide 40 mg single intravenous dose
Also known as: Buscopan
Group B, will receive 2 ml of normal saline single intravenous dose
Also known as: Saline
the duration of active phase of first stage of labor
time elapsed between start of active phase till full cervical dilatation
Time frame: 8 hours after hyoscine adminstration
Plan to share: Undecided
This study is completed, as verified in Sep 2021. You cannot join it, but the record below documents what was studied.
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Cairo University