Drug
Birinapant clinical trials
Also written TL32711.
- studies test it
- 12
- open now
- 0
- in phase 3
- 0
- first study started
- 2009
How studies write it
Studies that test it under each name
Development codes
Studies by the year they started
12 studies that test it; most in 2012 (2)
| Year | Studies |
|---|---|
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 2 |
| 2014 | 2 |
| 2017 | 1 |
| 2018 | 1 |
| 2019 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 10
- Phase 2
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 5
TetraLogic Pharmaceuticals (6) · National Cancer Institute (NCI) (2) · Roswell Park Cancer Institute (1) · Abramson Cancer Center at Penn Medicine (1) · Medivir (1) · Jonsson Comprehensive Cancer Center (1)
Often tested with
Tested in the same studies.
Azacitidine (1) · Conatumumab (1) · Gemcitabine (1) · Pembrolizumab (1) · Carboplatin (1)
Studies
Open first, then newest update. How each study uses birinapant is read from its arms, and is right about nine times in ten.
Testing it · 12
- Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell CarcinomaActive, not recruitingPhase 1National Cancer Institute (NCI)NCT03803774Written as Birinapant
- Birinapant and Carboplatin in Treating Patients and Targeting Recurrent High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (HGSOC)WithdrawnPhase 1/2Jonsson Comprehensive Cancer CenterNCT02756130Written as Birinapant
- Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid TumorsTerminatedPhase 1Roswell Park Cancer InstituteNCT01573780Written as Smac mimetic TL32711
- A Phase I-II Open Label Non-Randomized Study Using TL32711 for Patients With Acute Myelogenous Leukemia, Myelodysplastic Syndrome and Acute Lymphoblastic LeukemiaTerminatedPhase 1/2Abramson Cancer Center at Penn MedicineNCT01486784Written as Birinapant
- Dose-escalation Study of Birinapant and Pembrolizumab in Solid TumorsTerminatedPhase 1/2MedivirNCT02587962Written as Birinapant
- Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal CancerTerminatedPhase 2National Cancer Institute (NCI)NCT01681368Written as Birinapant (TL32711)
- Study of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoLTerminatedPhase 2TetraLogic PharmaceuticalsNCT02147873Written as birinapant
- Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid TumorsCompletedPhase 1/2TetraLogic PharmaceuticalsNCT01188499Written as Birinapant
- Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine TherapyCompletedPhase 1/2TetraLogic PharmaceuticalsNCT01828346Written as Birinapant
- Dose Escalation Safety Study of TL32711 in Adults With Refractory Solid Tumors or LymphomaCompletedPhase 1TetraLogic PharmaceuticalsNCT00993239Written as Birinapant (TL32711)
- Phase I Safety and Tolerability Study of Birinapant in Chronic Hepatitis BTerminatedPhase 1TetraLogic PharmaceuticalsNCT02288208Written as Birinapant
- Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian CancerCompletedPhase 1TetraLogic PharmaceuticalsNCT01940172Written as Birinapant
Given in every arm · 1 — birinapant is usual care beside what is tested
Codes
What other systems call birinapant · ClinicalTrials.gg INT006315
- MeSH (NLM) C582429birinapantOne source NLM
- UNII (FDA) 6O4Z07B57RBIRINAPANTConfirmed FDA, NLM, Wikidata
- Wikidata Q27075298birinapantConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C88295BirinapantOne source FDA
- DrugBank DB11782One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C582429 | birinapant | One source NLM |
| UNII (FDA) | 6O4Z07B57R | BIRINAPANT | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27075298 | birinapant | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C88295 | Birinapant | One source FDA |
| DrugBank | DB11782 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.