Drug
Avibactam clinical trials
Also written NXL104.
- studies test it
- 11
- open now
- 0
- in phase 3
- 0
- first study started
- 2008
How studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
11 studies that test it; most in 2011 (4)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2009 | 1 |
| 2010 | 1 |
| 2011 | 4 |
| 2012 | 2 |
| 2015 | 1 |
| 2017 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 7
- Phase 2
- 3
- Phase 4
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 2
Pfizer (7) · Forest Laboratories (2) · Michigan State University (1) · University of Southern California (1)
Often tested with
Tested in the same studies.
Ceftazidime (6) · Ceftaroline (3) · CAZ104 (2) · Metronidazole (1) · Aztreonam (1)
Studies
Open first, then newest update. How each study uses avibactam is read from its arms, and is right about nine times in ten.
Testing it · 11
- A Study of Avycaz (Ceftazidime/Avibactam) Pharmacokinetics/Pharmacodynamics (PK/PD) in Critically Ill PatientsCompletedPhase 1Michigan State UniversityNCT02822950Written as Ceftazidime/avibactam
- Steady-state Pharmacokinetics of Ceftazidime/Avibactam in Cystic FibrosisCompletedPhase 4University of Southern CaliforniaNCT02504827Written as Ceftazidime/avibactam
- Prospective Multicenter Doubleblind Randomized Study of NXL104/Ceftazidime + Metronidazole vs. Meropenem in Treatment of Complicated Intra-abdominal InfectionsCompletedPhase 2PfizerNCT00752219Written as ceftazidime/NXL104 + metronidazole
- Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract InfectionsCompletedPhase 2PfizerNCT00690378Written as NXL104/ceftazidime
- To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)CompletedPhase 1PfizerNCT01689207Written as Avibactam (AVI)
- A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and SeparatelyCompletedPhase 1PfizerNCT01430910Written as Avibactam
- Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]NXL104CompletedPhase 1PfizerNCT01448395Written as [14C]NXL104
- A Single-centre, Randomised, Double-blind, Placebo-controlled, Four Way Crossover Phase I Study to Investigate the Effect on QT/QTc Interval of Ceftazidime NXL104 or Ceftaroline Fosamil NXL104, Compared With Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male VolunteersCompletedPhase 1PfizerNCT01290900Written as NXL104
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of NXL104 Alone and in Combination With Ceftazidime Administered as Single and Repeated Intravenous Doses in Healthy Japanese SubjectsCompletedPhase 1PfizerNCT01291602Written as NXL104
- Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal ClearanceCompletedPhase 1Forest LaboratoriesNCT01624246Written as Ceftaroline fosamil/Avibactam (CXL)
- Comparative Study of Coadministered Ceftaroline Fosamil and NXL104 vs. Intravenous Doripenem in Adult Subjects With Complicated Urinary Tract InfectionsCompletedPhase 2Forest LaboratoriesNCT01281462Written as Ceftaroline fosamil and NXL104 (q8h)
As the comparator · 1 — what is tested is compared with avibactam
Codes
What other systems call avibactam · ClinicalTrials.gg INT005489
- MeSH (NLM) C543519avibactamConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 7352665165AVIBACTAMConfirmed FDA, NLM, Wikidata
- RxNorm 1603834Confirmed FDA, Wikidata
- Wikidata Q15410251avibactamConfirmed FDA, NLM, Wikidata
- Wikidata Q27158832avibactam sodiumConfirmed FDA, Wikidata
- NCI Thesaurus C171777AvibactamOne source FDA
- DrugBank DB09060One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C543519 | avibactam | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 7352665165 | AVIBACTAM | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1603834 | — | Confirmed FDA, Wikidata |
| Wikidata | Q15410251 | avibactam | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q27158832 | avibactam sodium | Confirmed FDA, Wikidata |
| NCI Thesaurus | C171777 | Avibactam | One source FDA |
| DrugBank | DB09060 | — | One source Wikidata |
Also registered as avibactam sodium (UNII 9V824P8TAI · RxNorm 1603833).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.