Drug
Artefenomel clinical trials
Also written OZ439.
Includes 1 study of Artefenomel mesylate.
- studies test it
- 16
- open now
- 0
- in phase 3
- 0
- first study started
- 2009
How studies write it
Studies that test it under each name
Studies by the year they started
16 studies that test it; most in 2012 (5)
| Year | Studies |
|---|---|
| 2009 | 1 |
| 2010 | 1 |
| 2012 | 5 |
| 2013 | 2 |
| 2015 | 5 |
| 2018 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
- Malaria
- 11
Who runs them
Industry 2 · Other 14
Often tested with
Tested in the same studies.
P-quaterphenyl (3) · Piperaquine (2) · Tocophersolan (2) · DSM265 (2) · Ferroquine (1)
Studies
Open first, then newest update. How each study uses artefenomel is read from its arms, and is right about nine times in ten.
Testing it · 16
- Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQPCompletedPhase 1Medicines for Malaria VentureNCT03542149Written as 200 mg OZ 439
- To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum MalariaTerminatedPhase 2SanofiNCT02497612Written as Artefenomel
- Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum MalariaCompletedPhase 2SanofiNCT03660839Written as Artefenomel (OZ439)
- A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax InfectionTerminatedPhase 1/2Medicines for Malaria VentureNCT02573857Written as OZ439
- Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking AgentCompletedPhase 1/2Medicines for Malaria VentureNCT02431650Written as OZ439
- OZ439 PhIIa Study in Plasmodium Falciparum: Extended ObservationCompletedPhase 2Medicines for Malaria VentureNCT01713621Written as OZ439
- Bioavailability Study of Oral OZ439 Prototype Granule Formulations Administered With Piperaquine Phosphate (PQP) TabletsCompletedPhase 1Medicines for Malaria VentureNCT02387580Written as OZ439 + TPGS
- A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265CompletedPhase 1/2Medicines for Malaria VentureNCT02389348Written as OZ439
- Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy VolunteersCompletedPhase 1Medicines for Malaria VentureNCT02453581Written as OZ439
- Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted StateCompletedPhase 1Medicines for Malaria VentureNCT01853475Written as OZ439+TPGS 800mg
- Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy VolunteersTerminatedPhase 1Medicines for Malaria VentureNCT01615822Written as OZ439 100mg
- A Dose-escalation Study to Investigate Safety and Toleration of OZ439CompletedPhase 1Medicines for Malaria VentureNCT01713608Written as OZ439
- Study To Investigate The Relative Bioavailability of OZ439 Formulations In Healthy VolunteersCompletedPhase 1Medicines for Malaria VentureNCT01383096Written as OZ439 mesylate 800mg Powder in Bottle for Oral Suspension
- Safety Tolerability & Pharmacokinetics of Co-administered Single Doses of OZ439 & Piperaquine to Healthy SubjectsCompletedPhase 1Medicines for Malaria VentureNCT01660022Written as 100mg OZ439 single oral dose
- A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female SubjectsCompletedPhase 1Medicines for Malaria VentureNCT00928083Written as OZ439 50mg API capsules
- Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infectionCompletedPhase 2Medicines for Malaria VentureNCT01213966Written as OZ439
Given in every arm · 1 — artefenomel is usual care beside what is tested
As the comparator · 1 — what is tested is compared with artefenomel
Codes
What other systems call artefenomel · ClinicalTrials.gg INT005826
- MeSH (NLM) C558165artefenomelConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) RIK029813GARTEFENOMELConfirmed FDA, NLM
- NCI Thesaurus C169787ArtefenomelOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C558165 | artefenomel | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | RIK029813G | ARTEFENOMEL | Confirmed FDA, NLM |
| NCI Thesaurus | C169787 | Artefenomel | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.