Analgesics, Non-Narcotic: all 3,330 studies that test it

Page 5 of 34. Open to participants first (511), then studies with results posted, then the rest; newest registration first within each.

• A Study of Intravenous Acetaminophen for Small Bowel ObstructionEnrolling by invitationNCT05878015Phase 4
• Propofol Versus Dexmedetomidine on the Incidence of Postoperative Nausea and VomitingRecruitingNCT05875077Not applicable
• Effect of Oral Dexmedetomidine, Ketamine, Or Midazolam as Preioperative Medications.RecruitingNCT05874245Phase 4
• Age-dependent Effects of Smoked and Oral Delta-9-THCRecruitingNCT05865470Phase 1
• Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by CardiometryNot yet recruitingNCT05860010Not applicable
• Efficacy of Dexmedetomidine VS Magnesium Sulphate With Bupivacaine in Erector Spinae Block for Thoracotomy PainRecruitingNCT05851768Not applicable
• Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac SurgeryRecruitingNCT05849597Phase 3
• Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic SurgeriesNot yet recruitingNCT05843344Not applicable
• Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias RepairRecruitingNCT05837000Phase 4
• Efficacy of Interleukin-2 in Triple Negative Breast CancerNot yet recruitingNCT05821686Phase 1/2
• Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic CancerNot yet recruitingNCT05810792Phase 2
• Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple SclerosisRecruitingNCT05809414Phase 3
• Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus BlockRecruitingNCT05793060Phase 4
• Quadruple Immunotherapy for NeuroblastomaRecruitingNCT05754684Phase 2
• Analgesic Additives to Epidural Bupivacaine in Normal LaborNot yet recruitingNCT05746351Not applicable
• Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal ColicsRecruitingNCT05722782Phase 2
• Dexmedetomidine in Postoperative AnalgesiaEnrolling by invitationNCT05705128Phase 2/3
• The Effect of Esmolol Versus Dexmedetomidine on Postoperative Pain Control in Endoscopic Sinus Surgery: A Randomized TrialRecruitingNCT05703048Not applicable
• Dexmedetomidine in Topical Versus Peribulbar Anesthesia for Cataract SurgeryRecruitingNCT05692167Phase 2
• Dexmedetomidine Plus Low Dose Morphine Versus Standard Dose of Morphine in PCA in Children .RecruitingNCT05688371Not applicable
• Effect of Sedative and Anxiolytic Premedication on Children Experience After General AnesthesiaRecruitingNCT05681572Phase 3
• Two-channel IV-PCA With DexmedetomidineRecruitingNCT05672225Not applicable
• TIL Cells for the Treatment of the Advanced Solid Tumors PatientsNot yet recruitingNCT05649618Early Phase 1
• TCR-T Cells for the Treatment NY-ESO-1-positive Advanced Solid TumorsNot yet recruitingNCT05648994Early Phase 1
• Analgesic Effect of a New Analgesic Based Gel(Douloff) Versus Oral Paracetamol in Acute Soft InjuriesNot yet recruitingNCT05647681Phase 1
• The Impact of THC on Pain Modulation in FibromyalgiaRecruitingNCT05644054Not applicable
• Multimodal Magnetoencephalography and Electroencephalography Exploration of the Acute Effects of THC Exposure on Neural Noise and Information Transmission Within Working Memory NetworksNot yet recruitingNCT05641766Phase 2
• Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass GraftingRecruitingNCT05640453Phase 4
• The Study of Comparing the Efficacy and Safety of Human Umbilical Cord MSCs and Low-dose IL-2 in the Treatment of LNRecruitingNCT05631717Phase 3
• Anti-inflammatory Drugs and Serum Prostate-Specific Antigen TestRecruitingNCT05629494Phase 4
• Oral Dexmedetomidine in Pediatric MRINot yet recruitingNCT05619627Phase 1
• Intranasal vs. IV Dexmedetomidine in Endoscopic Sinus SurgeryRecruitingNCT05595083Not applicable
• PRaG Regimens Rechallenge for Patients With Resistance to PD1/PD-L1 Inhibitors in Refractory Advanced Solid Tumors.Not yet recruitingNCT05530200Phase 2
• Cannabinoids for the Reduction of Inflammation and Sickle Cell Related PainRecruitingNCT05519111Phase 2
• Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIVRecruitingNCT05514899Phase 2
• Impact of Anti-inflammatory Medications in Patients With Elevated Serum Prostate-specific AntigenRecruitingNCT05512754Phase 4
• Intranasal Dexmedetomidine for Severe Dental Anxiety: a Randomized TrialNot yet recruitingNCT05500261Not applicable
• Amantadine for Neuroenhancement in Acute Patients StudyRecruitingNCT05479032Phase 2
• Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study.RecruitingNCT05439005Phase 3
• Behavioral Pharmacology of THC and Beta-MyrceneNot yet recruitingNCT05432284Phase 1
• Anxiolysis for Laceration Repair in ChildrenRecruitingNCT05383495Phase 3
• Proof of Concept Trial of Cannabis Derivatives in Neuropathic PainRecruitingNCT05351801Phase 2
• Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath DiameterNot yet recruitingNCT05340803Phase 3
• Co-administration of Acetaminophen With Ibuprofen to Improve Duct-Related Outcomes in Extremely Premature InfantsRecruitingNCT05340582Phase 2
• Efficacy and Immunological Evaluation of Telitacicept and Low Dose IL2 in the Treatment of Systemic Lupus ErythematosusRecruitingNCT05339217Phase 3
• PDA Treatment With Ibuprofen and Changes in Tissue Oxygenation.RecruitingNCT05325177Phase 4
• THC Effects on Glucose in Type 2 DiabetesRecruitingNCT05322213Phase 1
• A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)RecruitingNCT05319730Phase 1/2
• IV Acetaminophen After Cardiac Surgery - PILOTRecruitingNCT05246644Phase 3
• Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's DiseaseNot yet recruitingNCT05197439Not applicable
• Effect of Dexmedetomidine on Postoperative Delirium After Awake CraniotomiesRecruitingNCT05195034Not applicable
• Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid TumorsRecruitingNCT05141474Early Phase 1
• Promoting Recovery After STroke With AmantadineRecruitingNCT05140148Phase 2
• Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related CoughRecruitingNCT05120934Phase 2
• Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic CoughRecruitingNCT05110144Phase 2
• Evaluation of Oral THC and CBD in Men and WomenRecruitingNCT05067387Phase 1
• Safety and Efficacy of Oral Cannabis in Chronic Spine PainRecruitingNCT05052541Phase 3
• Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart SurgeryRecruitingNCT05029050Phase 4
• Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar DisorderRecruitingNCT05025605Phase 1
• Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCTRecruitingNCT05011149Phase 3
• Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the KneeRecruitingNCT04992624Phase 2
• PAIR (Paracetamol and Ibuprofen Research) Pilot TrialRecruitingNCT04986839Phase 2/3
• Th Effects of a Drug Dexmedotemidine in Regional Anesthesia in Participants Undergoing Upper Limb SurgeriesRecruitingNCT04981951Not applicable
• Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant DepressionRecruitingNCT04936126Phase 4
• Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture RibsRecruitingNCT04928300Phase 3
• Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial InfarctionRecruitingNCT04912518Not applicable
• Cannabis Use, Cognition, and the Endocannabinoid System in HIVRecruitingNCT04883255Early Phase 1
• Acetaminophen and AKI After Aortic SurgeryRecruitingNCT04882202Not applicable
• Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsiaRecruitingNCT04873596Phase 2
• Effect of Quinine Hydrochloride in Overweight Population on Food Intake, Hunger and Gut Peptide ReleaseRecruitingNCT04873011Phase 1
• Effects of Dexmedetomidine in Patients With Agitated Delirium in Palliative CareRecruitingNCT04824144Phase 1/2
• Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural SedationRecruitingNCT04822064Not applicable
• Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study IIRecruitingNCT04704271Phase 1
• Pediatric DeliriumEnrolling by invitationNCT04669457Phase 4
• Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine SurgeriesRecruitingNCT04628663Not applicable
• Post-operative Analgesic Effect of Oral NefopamRecruitingNCT04576078Phase 2
• Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar DiscectomyRecruitingNCT04574778Phase 3
• The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer SurgeryRecruitingNCT04454515Not applicable
• a Phase III Trial of Safety and Efficacy of Premedication With Dexmedetomidine and Midazolam in Pediatric PatientsRecruitingNCT04356638Phase 3
• Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised TrialRecruitingNCT04302870Phase 2/3
• Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery PatientsRecruitingNCT04289142Phase 4
• Effect of Paracetamol on Kidney Function in Severe MalariaRecruitingNCT04251351Phase 3
• Stem Cell Transplantation in Crohn's DiseaseRecruitingNCT04224558Phase 1/2
• A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.RecruitingNCT04166006Phase 2
• Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal SurgeryRecruitingNCT04144933Phase 3
• Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute Low Back PainRecruitingNCT04111315Phase 4
• Optimizing Pain Control in Transurethral Resection of the ProstateRecruitingNCT04102566Phase 4
• Sedation Efficacy of Dexmedetomidine Versus Midazolam in Critically Ill Ventilated ChildrenRecruitingNCT04082767Phase 3
• Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain ManagementRecruitingNCT04059172Early Phase 1
• Effects of Dronabinol in Opioid Maintained PatientsRecruitingNCT04025359Early Phase 1
• Treating Postictal Symptoms Using Ibuprofen and NifedipineRecruitingNCT03949478Phase 2
• Individualized Tumor Specific TCR- T Cells in the Treatment of Advanced Solid TumorsRecruitingNCT03891706Phase 1
• Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic SurgeryRecruitingNCT03858231Phase 4
• Efficacy of Nitrous Oxide in OCD: Pilot StudyRecruitingNCT03826693Phase 2
• Nonopioid Analgesia After Labral SurgeryRecruitingNCT03825809Phase 2/3
• Supracondylar Post-Operative Pain StudyRecruitingNCT03759028Phase 4
• Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity SurgeryRecruitingNCT03756961Not applicable
• Nitrous Oxide- Suicidal IdeationEnrolling by invitationNCT03736538Phase 1
• A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing ChangesRecruitingNCT03695887Early Phase 1
• Paracetamol Study in Patients With Low Muscle MassRecruitingNCT03648658Phase 4

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