Drug
Amivantamab clinical trials
Also written JNJ-61186372 and RYBREVANT.
- studies test it
- 33
- open now
- 12
- in phase 3
- 7
- first study started
- 2018
Keep track of what changes. Save the amivantamab studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Brand
Development codes
Other names
Combined with it in one product
Studies by the year they started
33 studies that test it; most in 2023 (7)
| Year | Studies |
|---|---|
| 2018 | 1 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 4 |
| 2022 | 5 |
| 2023 | 7 |
| 2024 | 7 |
| 2025 | 3 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 9
- Phase 2
- 24
- Phase 3
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 18 · Other 15
Janssen Research & Development, LLC (16) · Memorial Sloan Kettering Cancer Center (2) · Latin American Cooperative Oncology Group (2) · Yonsei University (2) · University of Colorado, Denver (1) · M.D. Anderson Cancer Center (1) · AstraZeneca (1) · Institute of Cancer Research, United Kingdom (1)
Often tested with
Tested in the same studies.
Lazertinib (6) · Dexamethasone (1) · Montelukast (1) · Methotrexate (1) · Capmatinib (1) · Cetrelimab (1) · Tepotinib (1) · Osimertinib (1)
Studies
Open first, then newest update. How each study uses amivantamab is read from its arms, and is right about nine times in ten.
Testing it · 33
- Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)RecruitingPhase 2SWOG Cancer Research NetworkNCT06116682Written as Amivantamab
- A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received ChemotherapyRecruitingPhase 3Janssen Research & Development, LLCNCT06750094Written as Amivantamab
- A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal CancerRecruitingPhase 3Janssen Research & Development, LLCNCT06662786Written as Amivantamab
- A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal CancerRecruitingPhase 1/2Janssen Research & Development, LLCNCT05379595Written as Amivantamab IV
- A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck CancerRecruitingPhase 3Janssen Research & Development, LLCNCT07276399Written as Amivantamab
- A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung CancerRecruitingPhase 1/2Janssen Research & Development, LLCNCT07227025Written as Amivantamab
- Amivantamab in Patients With Metastatic/Recurrent Penile Squamous Cell CarcinomaNot yet recruitingPhase 2Latin American Cooperative Oncology GroupNCT07808359Written as Amivantamab
- Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)RecruitingPhase 2Gruppo Oncologico del Nord-OvestNCT05845450Written as Amivantamab
- Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients With EGFR-mutant, Locally Advanced or Metastatic/Recurrent Non-Small Cell Lung Cancer (INSTAR Study)Not yet recruitingPhase 2Yonsei UniversityNCT07507188Written as Amivantamab SC + Chemotherapy (Carboplatin IV & Pemetrexed IV)
- Phase II Trial of Amivantamab Plus Monochemotherapy in Platinum Unfit NSCLC Patients With EGFR exon20 Insertion Mutations.RecruitingPhase 2Fondazione Ricerca TraslazionaleNCT07392658Written as Amivantamab
- An Open-label, Single-arm, Multicenter Phase II Study to Evaluate the Efficacy of Amivantamab in Combination With FOLFIRI as a Second-line Treatment in Patients With RAS/BRAF Wild-type Advanced Colorectal Cancer Progressing on Prior Anti-EGFR Based Treatment.Not yet recruitingPhase 2Yonsei UniversityNCT06855849Written as Amivantamab + FOLFIRI
- A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)RecruitingPhase 2Vall d'Hebron Institute of OncologyNCT03767075Written as Amivantamab
- Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET AlterationsActive, not recruitingPhase 1/2University of Colorado, DenverNCT05845671Written as Amivantamab 1050mg
- A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung CancerActive, not recruitingPhase 3Janssen Research & Development, LLCNCT04487080Written as Amivantamab
- A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung CancerActive, not recruitingPhase 3Janssen Research & Development, LLCNCT05388669Written as Amivantamab Subcutaneous and Co-Formulated with Recombinant Human Hyaluronidase (SC CF)
- A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib FailureActive, not recruitingPhase 3Janssen Research & Development, LLCNCT04988295Written as Amivantamab
- Premedication to Reduce Amivantamab Associated Infusion Related ReactionsActive, not recruitingPhase 2Janssen Research & Development, LLCNCT05663866Written as Amivantamab
- A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung CancerActive, not recruitingPhase 1/2Janssen Research & Development, LLCNCT05488314Written as Amivantamab
- Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus LazertinibActive, not recruitingPhase 2Janssen Research & Development, LLCNCT06120140Written as Amivantamab IV
- A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung CancerActive, not recruitingPhase 1/2Janssen Research & Development, LLCNCT05908734Written as Amivantamab
See all 33 studies that test amivantamab →
Given in every arm · 9 — amivantamab is usual care beside what is tested
- A Study of JNJ-95437446 in Participants With Advanced-Stage Solid TumorsRecruitingPhase 1Janssen Research & Development, LLCNCT07107230Written as Amivantamab
- A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung CancerRecruitingPhase 2Janssen Research & Development, LLCNCT05498428Written as Amivantamab
- A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck CancerRecruitingPhase 1/2Janssen Research & Development, LLCNCT06385080Written as Amivantamab
- A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)RecruitingPhase 2Janssen Research & Development, LLCNCT06667076Written as Amivantamab
- A Study of Neoadjuvant Amivantamab With Either Lazertinib or Chemotherapy in Participants With Resectable EGFR-Mutated NSCLCRecruitingPhase 2Janssen Research & Development, LLCNCT07586202Written as Amivantamab
- Preoperative Amivantamab or Amivantamab and Carboplatin/Pemetrexed Treatment in Patients With Resectable Non-small-cell Lung Cancer Harboring Oncogenic EGFR Mutations (NEOpredict-EGFR)RecruitingPhase 2University Hospital, EssenNCT06784791Written as Amivantamab Intravenous
- Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung CancerActive, not recruitingPhase 1Janssen Research & Development, LLCNCT02609776Written as Amivantamab
- A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid MalignanciesActive, not recruitingPhase 1Kumquat Biosciences Inc.NCT06507306Written as Amivantamab
- FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid TumorsTerminatedPhase 1Fate TherapeuticsNCT05395052Written as Amivantamab
Codes
What other systems call amivantamab · ClinicalTrials.gg INT001661
- MeSH (NLM) C000718215amivantamabConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 0JSR7Z0NB6AMIVANTAMABConfirmed FDA, NLM, Wikidata
- RxNorm 2549199One source FDA
- Wikidata Q106957199amivantamabConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C124993AmivantamabOne source FDA
- DrugBank DB16695One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000718215 | amivantamab | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 0JSR7Z0NB6 | AMIVANTAMAB | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2549199 | — | One source FDA |
| Wikidata | Q106957199 | amivantamab | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C124993 | Amivantamab | One source FDA |
| DrugBank | DB16695 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.