Allogeneic TGFBR2 KO CAR27/IL-15-expressing NK Cells clinical trials
How each study uses Allogeneic TGFBR2 KO CAR27/IL-15-expressing NK Cells is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Name
- TGFBR2 KO CAR27/IL-15 NK cells
- 4
Studies by the year they started
4 studies that test it; most in 2026 (3)
| Year | Studies |
|---|---|
| 2025 | 1 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 0 · Other 4
Studies
Open first, then newest update. How each study uses Allogeneic TGFBR2 KO CAR27/IL-15-expressing NK Cells is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 4
- Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The PeritoneumRecruitingPhase 1/2M.D. Anderson Cancer CenterNCT07509008Written as TGFBR2 KO CAR27/IL-15 NK cells
- Phase1 Basket Trial Of CAR.70-Engineered IL15-Transduced With TGFBR2 Knock Out Cord Blood-Derived NK Cells For Relapsed/Refractory Lymphoid MalignanciesRecruitingPhase 1M.D. Anderson Cancer CenterNCT07444632Written as TGFBR2 KO CAR27/IL-15 NK cells
- A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid MalignanciesRecruitingPhase 1/2M.D. Anderson Cancer CenterNCT06930651Written as TGFBR2 KO CAR27/IL-15 NK cells
- TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic CancerSuspendedPhase 1/2M.D. Anderson Cancer CenterNCT07377526Written as TGFBR2 KO CAR27/IL-15 NK cells