Acetylcysteine: all 450 studies that test it

Page 1 of 5. Open to participants first (62), then studies with results posted, then the rest; newest registration first within each.

• NAC for Hematopoietic Recovery in Low/Intermediate-Risk AML After CR: A Randomized Controlled StudyNot yet recruitingNCT07869342Not applicable
• N-Acetylcysteine in the Management of Spontaneous Bacterial PeritonitisNot yet recruitingNCT07803952Phase 1/2
• Role of N-Acetylcysteine in Non-Acetaminophen-Induced Liver FailureRecruitingNCT07765823Not applicable
• Prophylactic NAC to Improve Platelet Engraftment After Haploidentical Transplantation in Severe Aplastic Anemia PatientsNot yet recruitingNCT07737262Phase 3
• To Evaluate the Efficacy and Safety of N-acetyl Cysteine Administration in Patients With Diabetic RetinopathyRecruitingNCT07634991Phase 4
• Therapeutics for Moderate and Severe DengueNot yet recruitingNCT07543458Phase 3
• Evaluation of the Combined Therapy of EH-301 and N-acetylcysteine Together With Riluzole in Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07414212Phase 1/2
• Effect of Acetylcysteine Inhalation on Incidence and Time to Develop Ventilator Associated Pneumonia in Critically Ill Mechanically Ventilated PatientsRecruitingNCT07409727Phase 4
• Imaging Acetadote Metabolism in GlioblastomaRecruitingNCT07387666Early Phase 1
• Effect of N-acetylcysteine as Adjunct Therapy on the Clinical Outcome of Neonatal SepsisNot yet recruitingNCT07380347Phase 3
• Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled TrialRecruitingNCT07364747Phase 2
• Comparing N-Acetylcysteine (NAC) Versus Alpha-Lipoic Acid (ALA) as Adjuncts for Postoperative Pain Management After Laparoscopic AppendectomyNot yet recruitingNCT07360379Not applicable
• The MIND Study: The MGH/MIT Investigation of NAC on DysregulationNot yet recruitingNCT07323446Early Phase 1
• Microbiological Characteristics of Biofilm on Double J Ureteral Stents After Lithotripsy.Not yet recruitingNCT07301294Phase 4
• Individualized Multiplex Pathophysiological Treatment of Severe Acute Infections: N-AcetylcysteineRecruitingNCT07273071Phase 4
• NAC-REPAIR for Post-surgical PainNot yet recruitingNCT07227649Phase 2
• Redox Status and Exercise Training-induced AdaptationsRecruitingNCT07196852Not applicable
• Evaluating the Effect of N-Acetyl Cysteine and Alpha Lipoic Acid in Patients With Beta ThalassemiaNot yet recruitingNCT07157722Phase 3
• N-Acetylcysteine Roles in Preserving Renal Function Measured by Urinary KIM-1 (Kidney Injury Molecule-1) and Serum Creatinine on Cancer Patients With Cisplatin Based Chemotherapy: A Randomized Placebo-Controlled TrialNot yet recruitingNCT07156786Phase 2/3
• A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function RecoveryNot yet recruitingNCT07136987Phase 3
• An Open-Label, Bayesian Adaptive Phase II Clinical Study in HR+/HER2- Advanced Breast Cancer After Progression on Standard TherapyRecruitingNCT07117630Phase 2
• Comparison of the Outcome of Treatment With Silymarin or N-Aceylcysteine in Patients Taking Anti-Tuberculous Drugs for Tuberculosis at a Tertiary Care Hospital , KarachiNot yet recruitingNCT07058090Phase 1
• BabySTrong II taVNS Feeding TrialRecruitingNCT07049952Phase 2/3
• PROlonged Corticosteroid Treatment or N-ACetylcysteine for Severe Alcoholic HepatitisRecruitingNCT06956482Phase 3
• A Confirmatory Trial of Adjunctive NAC to Prevent Post Tuberculosis Lung DiseaseRecruitingNCT06909799Not applicable
• The Anti-Anginal Effects of N-Acetylcysteine (NAC) in Patients with Angina and Non-Obstructive Coronary Arteries (ANOCA)Not yet recruitingNCT06890507Phase 2
• The Efficacy of Dexamethasone in Combination With N-acetylcysteine in Preventing Neurocognitive Sequelae Due to Carbon Monoxide PoisoningRecruitingNCT06811675Phase 4
• A Pilot Trial of Tapering Antipsychotics for Patients in Remitted Psychosis Co-administering With N-AcetylcysteineNot yet recruitingNCT06546475Phase 4
• NAC for Hematopoietic Recovery in SAANot yet recruitingNCT06518044Phase 2
• Gene-guided N-acetyl Cysteine for Prophylaxis of Anti-tuberculous Drug- Induced HepatitisRecruitingNCT06484530Phase 4
• Efficacy & Safety of Dry Powder Ivy Extract (Syrup Prospan) Versus NAC Among COPD PatientsRecruitingNCT06377410Not applicable
• Effects of Protein and NAC Co-ingestion on Skeletal Muscle RecoveryRecruitingNCT06367413Not applicable
• Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer PatientsRecruitingNCT06297369Phase 2
• Tolerability of Enteral NAC in InfantsNot yet recruitingNCT06260566Phase 1
• Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort StudyRecruitingNCT06165068Phase 3
• Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung DiseaseRecruitingNCT05986318Phase 2
• The Use of N-acetylcysteine for Thrombotic Events After Allogenic Hematopoietic Stem Cell TransplantationNot yet recruitingNCT05907486Phase 3
• Using Acetylcysteine and Vitamin E With Psoriasis VulgarisRecruitingNCT05906498Phase 3
• Efficiency of a Composite Personalised Care on Functional Outcome in Early PsychosisRecruitingNCT05796401Phase 3
• N-acetylcysteine (NAC) for the Treatment of Acute Exacerbation of COPDRecruitingNCT05706402Phase 3
• Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: TrialRecruitingNCT05664789Phase 2/3
• A Randomised Controlled Trial, of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion CarriersRecruitingNCT05509153Phase 2
• Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open LabelEnrolling by invitationNCT05494398Phase 2/3
• A Randomised Controlled Trial of N-acetylcysteine for the Management of Alcohol Use DisorderRecruitingNCT05408247Phase 4
• Impact of N-acetylcysteine Infusion and Intralipid Infusion on Myocardial Injury in Aluminum Phosphide ToxicityNot yet recruitingNCT05370729Not applicable
• Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione LevelsRecruitingNCT05241262Phase 1
• Effects of NAC on Symptoms of CHR PatientsRecruitingNCT05142735Not applicable
• AZA Combined With NAC for PIT After HSCTNot yet recruitingNCT05126004Phase 2
• An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative NeoplasmsRecruitingNCT05123365Phase 1/2
• NAC for Attenuation of COVID-19 SymptomatologyNot yet recruitingNCT05074121Phase 2
• GWICTIC: NAC Mechanistic Study in Gulf War VeteransRecruitingNCT04987775Early Phase 1
• Outcomes of Patients After Allo-HSCT With Decitabine and NACNot yet recruitingNCT04945096Phase 3
• Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBTRecruitingNCT04520139Phase 1/2
• The ACTS Trial: N-acetylcysteine (NAC) and Night-splinting as a Non-operative Treatment for Carpal Tunnel SyndromeRecruitingNCT04460521Phase 4
• Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal DystrophyRecruitingNCT04440280Phase 2
• Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange SyndromeNot yet recruitingNCT04381897Phase 2
• Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-doseRecruitingNCT04278898Phase 2
• Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and PneumoniaRecruitingNCT03900988Phase 3
• Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)RecruitingNCT03652753Phase 4
• PET-MRI in Chronic Traumatic Brain Injury (CTBI)Enrolling by invitationNCT03241732Not applicable
• N-ACetylcysteine to Reduce Infection and Mortality for Alcoholic HepatitisRecruitingNCT03069300Phase 3
• Physiological Effects of N-Acetyl Cysteine in Patients With Multiple SclerosisEnrolling by invitationNCT03032601Not applicable
• Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar DisorderCompletedNCT05340504Phase 2Results posted
• Oxidative Stress and Surgical RecoveryCompletedNCT04732000Phase 2Results posted
• N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-UseCompletedNCT04627922Phase 4Results posted
• Efficacy and Safety of Rifaximin With NAC in IBS-DCompletedNCT04557215Phase 1/2Results posted
• Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1CompletedNCT04481048Phase 2Results posted
• Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1CompletedNCT04481035Phase 2Results posted
• Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric PatientsCompletedNCT04291066Phase 2Results posted
• Neurocircuit Strategy to Decrease Cocaine Cue ReactivityCompletedNCT04155632Phase 2Results posted
• Efficacy and Safety of Acetylcysteine for the Treatment of Acute Uncomplicated RhinosinusitisCompletedNCT04123405Phase 3Results posted
• The Effects of Kynurenine Aminotransferase Inhibition in People With SchizophreniaCompletedNCT04013555Phase 1/2Results posted
• Signatures of N-Ac for Non-Suicidal Self-Injury in AdolescentsCompletedNCT04005053Phase 2Results posted
• A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Single and Multiple Intravenous Doses of N-acetylcysteine (NAC) in Chinese Healthy VolunteersCompletedNCT03881163Phase 1Results posted
• A Clinical Trial to Compare the Efficacy and Safety of 1-week Treatment of Intravenous N-acetylcysteine (NAC) 600 mg Twice Daily, Ambroxol Hydrochloride 30 mg Twice Daily and Placebo as Expectorant Therapies in Adult Chinese Patients With Respiratory Tract Diseases and Abnormal Mucus SecretionsCompletedNCT03843541Phase 3Results posted
• N-Acetylcysteine for Adolescent Alcohol Use DisorderCompletedNCT03707951Phase 2Results posted
• NAC for Head Trauma-induced AnosmiaTerminatedNCT03680911Phase 3Results posted
• Inpatient Clinical Trial of NACTerminatedNCT03581084Phase 4Results posted
• N-Acetylcysteine in Biliary Atresia After Kasai PortoenterostomyCompletedNCT03499249Phase 2Results posted
• Memory and Antioxidants in Vascular Impairment TrialCompletedNCT03306979Phase 2Results posted
• N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of DiabetesCompletedNCT03253328Early Phase 1Results posted
• A Safety and Efficacy Study of NAC in Patients With TA-TMACompletedNCT03252925Phase 3Results posted
• Neuroscience-Informed Treatment Development for Adolescent Alcohol UseCompletedNCT03238300Phase 2Results posted
• Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics AlcoholicsCompletedNCT03220776Phase 2Results posted
• PP100-01 (Calmangafodipir) for Overdose of ParacetamolCompletedNCT03177395Phase 1Results posted
• Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease?TerminatedNCT03104725Phase 1Results posted
• N-Acetylcysteine for Youth Cannabis Use DisorderCompletedNCT03055377Phase 2/3Results posted
• A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum DisorderCompletedNCT03008889Phase 2Results posted
• Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)CompletedNCT02966873Phase 2Results posted
• NAC for Treating Comorbid PTSD and SUDCompletedNCT02911285Phase 2Results posted
• A Study of Oxidative Pathways in MS FatigueCompletedNCT02804594Phase 2Results posted
• N-acetylcysteine Treatment of Alcohol Use Disorder In Veterans With TBICompletedNCT02791945Phase 2Results posted
• N-acetylcysteine for Tobacco Use DisorderCompletedNCT02737358Phase 2Results posted
• Translational Neuropsychopharmacology Research of Nicotine AddictionCompletedNCT02723162Phase 2Results posted
• A Study to Assess the Safety and Tolerability of N-Acetylcysteine When Administered With Pirfenidone to Participants With Idiopathic Pulmonary Fibrosis (IPF)CompletedNCT02707640Phase 2Results posted
• Effects of N-acetylcysteine on Cardiorespiratory Control in COPD Patients With Mild-to-moderate Airflow ObstructionCompletedNCT02579772Phase 4Results posted
• Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube CancerTerminatedNCT02569957Phase 2Results posted
• Use of NAC in Alleviation of Hangover SymptomsCompletedNCT02541422Not applicableResults posted
• N-acetylcysteine in the Treatment of PTSD and AddictionCompletedNCT02499029Phase 2Results posted
• Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and CoughCompletedNCT02379637Phase 2Results posted

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