Acetaminophen: all 653 studies that test it

Page 3 of 7. Open to participants first (58), then studies with results posted, then the rest; newest registration first within each.

• Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial MeningitisCompletedNCT01540838Phase 4Results posted
• Structured Non-operative Treatment of Knee OsteoarthritisCompletedNCT01535001Not applicableResults posted
• Intravenous Acetaminophen Use With Bariatric Surgery on Morbidly Obese PatientsTerminatedNCT01527942Not applicableResults posted
• Efficacy of Oral Versus Intravenous Acetaminophen for Primary Pediatric Cleft Palate RepairCompletedNCT01500109Not applicableResults posted
• Effects of a Common Cold Treatment on Cognitive FunctionCompletedNCT01466348Phase 4Results posted
• Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and FluCompletedNCT01448057Phase 3Results posted
• Maxigesic 325 Acute Dental Pain StudyCompletedNCT01420653Phase 3Results posted
• Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion PatientsCompletedNCT01394718Phase 3Results posted
• Inhibition of Lipid Peroxidation During Cardiac SurgeryCompletedNCT01366976Not applicableResults posted
• The Post-Operative Pain Management of Pediatric Supracondylar Elbow FracturesCompletedNCT01328782Not applicableResults posted
• Sleep Disruption in New Mothers: An Intervention TrialCompletedNCT01321710Not applicableResults posted
• High Pain Intervention in Cesarean SectionsCompletedNCT01298778Not applicableResults posted
• Effect of Paracetamol on the Common ColdCompletedNCT01277081Phase 2Results posted
• A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing TonsillectomyCompletedNCT01267136Phase 4Results posted
• Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of MigraineCompletedNCT01248468Phase 4Results posted
• Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain StudyCompletedNCT01229449Phase 3Results posted
• To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After SurgeryCompletedNCT01115673Phase 3Results posted
• An Efficacy and Safety Study of Extended Release (ER) Tramadol Hydrochloride (HCl)/Acetaminophen in Participants With Chronic Low-Back PainCompletedNCT01112267Phase 3Results posted
• Assess the Blood-Oxygen-Level-Dependent (BOLD) Signal Changes in the Brain by Paracetamol as Measured by Functional Magnetic Resonance Imaging (fMRI) in Subjects With Osteoarthritis (OA)CompletedNCT01105936Phase 4Results posted
• Post-operative Dental Pain Study Comparing Analgesic EfficacyCompletedNCT01082081Phase 4Results posted
• Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic EfficacyCompletedNCT01075243Phase 4Results posted
• Effect of Race/Ethnicity and Genes on Acetaminophen PharmacokineticsCompletedNCT00768716Phase 4Results posted
• An Efficacy Study of Combination of Tramadol and Acetaminophen Tablets in the Treatment of Participants With Fibromyalgia PainCompletedNCT00766675Phase 4Results posted
• Aminotransferase Trends During Prolonged Acetaminophen DosingCompletedNCT00743093Phase 4Results posted
• A Comparative Study of JNS013 in Participants With Post-Tooth-Extraction PainCompletedNCT00737048Phase 3Results posted
• A Long-term Efficacy and Safety Study of Tramadol Hydrochloride Plus Acetaminophen (JNS013) in Japanese Participants With Chronic PainCompletedNCT00736957Phase 3Results posted
• An Efficacy and Safety Study of Acetaminophen Plus Tramadol Hydrochloride (JNS013) in Participants With Chronic PainCompletedNCT00736853Phase 3Results posted
• Mechanisms of Action of AcetaminophenCompletedNCT00646906Not applicableResults posted
• A Comparative Study of Tramadol Hydrochloride Plus Acetaminophen Tablets Maintenance Versus Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Maintenance in Participants With Knee OsteoarthritisCompletedNCT00635349Phase 4Results posted
• A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic NeuropathyCompletedNCT00634543Phase 4Results posted
• Acetaminophen Adduct Formation in Non-Drinkers Taking Therapeutic Doses of Acetaminophen for Ten Consecutive DaysCompletedNCT00616018Phase 4Results posted
• Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric InpatientsCompletedNCT00598702Phase 3Results posted
• Safety and Efficacy of Intravenous Acetaminophen (IV APAP) in Adult InpatientsCompletedNCT00598559Phase 3Results posted
• Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult MalesCompletedNCT00564629Phase 3Results posted
• Analgesic Efficacy & Safety of Intravenous (IV) Acetaminophen Versus Placebo for the Treatment of Postop PainCompletedNCT00564486Phase 3Results posted
• Safety of Intravenous Acetaminophen Vs Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult MalesCompletedNCT00493311Phase 3Results posted
• Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric InpatientsCompletedNCT00493246Phase 1Results posted
• Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post-menopausal Women With Low Bone MassCompletedNCT00489424Phase 4Results posted
• Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic SurgeryCompletedNCT00399568Phase 3Results posted
• Acetaminophen for Fetal Tachycardia: a Randomized Pilot TrialTerminatedNCT00377832Not applicableResults posted
• Acetaminophen Before Vaccines for Infants Study (AVIS)CompletedNCT00325819Phase 3Results posted
• A Comparison of the Addiction Liability of Hydrocodone and Sustained Release MorphineCompletedNCT00314340Phase 4Results posted
• Ibuprofen Alone and in Combination With Acetaminophen for Treatment of FeverCompletedNCT00267293Phase 4Results posted
• Allogeneic Transplantation From Related Haploidentical DonorsCompletedNCT00185692Phase 2Results posted
• Maxigesic for Postoperative Pain Control After Laparoscopic or Robotic GastrectomyActive, not recruitingNCT07768514Phase 2
• Elevation of Effect of Common Analgesic on Pulp Sensibility TetCompletedNCT07618494Not applicable
• A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or ObesityActive, not recruitingNCT07508241Phase 1
• Intravenous Paracetamol Versus Intramuscular Tramadol in Shortening the Duration of Labour.CompletedNCT07394491Not applicable
• Elective Total Abdominal Hysterectomy With Preoperative Analgesia Intravenous Paracetamol Versus PlaceboCompletedNCT07368790Not applicable
• Efficacy of Oral Paracetamol Compared With Oral Ketoprofen for Pain Management in Office HysteroscopyCompletedNCT07315698Phase 4
• Effect of Common Analgesia on Pulp SensibilityCompletedNCT07125911Not applicable
• Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous TherapiesActive, not recruitingNCT07102641Phase 4
• Acetaminophen Before Surgery Lowers Postop Pain in Pediatric Solid Tumor Patients (ERAS)CompletedNCT07095816Phase 1
• Pain Control After Open Radical Nephrectomy: Thoracic Paravertebral Block Versus External Oblique Intercostal BlockCompletedNCT07071012Not applicable
• Prophylactic IV Paracetamol in Extremely Premature InfantsCompletedNCT07067177Phase 2/3
• Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery.Active, not recruitingNCT07002788Not applicable
• Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental PainCompletedNCT06916234Phase 4
• Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute ExacerbationCompletedNCT06863636Phase 3
• Variability of Sulfotransferase Activity in Humans: an Approach to Improve Predictive Drug Response Part II: Analysis of Interindividual Variation in Hypertensive PatientsCompletedNCT06782204Phase 1
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-4729 Injection in Healthy SubjectsCompletedNCT06762600Phase 1
• Analgesic Effects of Intranasal Diclofenac Sodium, Ibuprofen, and Paracetamol in Pediatric Tonsillectomy CasesCompletedNCT06731556Phase 3
• A Study of Efinopegdutide in Healthy Obese Participants (MK-6024-015)CompletedNCT06701305Phase 1
• Pain After Strabismus SurgerySuspendedNCT06689943Phase 2
• Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and InfantsActive, not recruitingNCT06647407Phase 1/2
• Pain Management Following Dental Treatment Under General AnesthesiaCompletedNCT06574516Not applicable
• Approach to Ankle Sprains in the Emergency DepartmentCompletedNCT06563271Phase 4
• Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol, Meperidine, and Paracetamol in Renal ColicCompletedNCT06558916Phase 4
• Patient Controlled Administration of Liquid AcetaminophenCompletedNCT06498713Phase 1
• A Randomized Control Trial on Intravenous Paracetamol Versus Intramuscular Tramadol as Intra Partum Labor AnalgesiaCompletedNCT06371144Phase 2
• An Acute Migraine Factorial StudyCompletedNCT06245902Phase 2
• Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)CompletedNCT06180070Phase 1
• The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKACompletedNCT06112548Not applicable
• Heamodynamic Effects of Paracetamol in Septic Shock PatientsCompletedNCT06076980Phase 4
• Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis PatientsCompletedNCT06061575Phase 4
• Evaluation of Broccoli Seed and Sprout Extract for Detoxification of Carcinogens in FirefightersActive, not recruitingNCT06009926Phase 2
• Paracetamol Plus Tramadol Versus Fentanyl in Day Case SurgeriesCompletedNCT05990686Phase 4
• Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal SurgeryWithdrawnNCT05965492Phase 3
• Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac SurgeryCompletedNCT05853263Not applicable
• A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With PainCompletedNCT05844995Phase 1
• Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly PatientsTerminatedNCT05834569Phase 4
• Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Treatment in Spinal SurgeryCompletedNCT05764707Phase 2
• Efficacy of Parecoxib Combined With Paracetamol in MastectomyStatus unknownNCT05757388Not applicable
• Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee OsteoarthritisWithdrawnNCT05742763Phase 1/2
• Preemptive and Preventive Acetaminophen/Ibuprofen Fixed-dose Combination After Robot-assisted Radical ProstatectomyCompletedNCT05685342Not applicable
• Single-Site Study of Naltrexone/Acetaminophen for the Acute Treatment of Migraine: A Phase 2 Randomized TrialWithdrawnNCT05685225Phase 2
• Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial CraniotomyCompletedNCT05681429Not applicable
• Effectiveness of Pre-emptive Analgesics on Post-Operative Pain After Stainless Steel Crown Placement On Primary MolarsCompletedNCT05602064Phase 4
• Efficacy and Safety of Acetaminophen in Postoperative Pain Management of InfantsCompletedNCT05564819Phase 1
• Oral vs IV Acetaminophen for Long-bone Fracture in ChildrenStatus unknownNCT05557344Phase 4
• Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb ArthritisTerminatedNCT05556356Phase 4
• Multimodal and Unimodal Analgesia in CholecystectomyCompletedNCT05547659Phase 1/2
• Evaluation of the Efficacy of Different Drugs in the Treatment of the Pain in Patients With Temporomandibular DisorderCompletedNCT05529290Phase 4
• Paracetamol Compared With Ketorolac for Post-operative AnalgeticCompletedNCT05523102Phase 4
• Epidural Tap in Labor Analgesia FOR LABOR ANALGESIACompletedNCT05499234Not applicable
• Effect of Estrogen Treatment on Drug Metabolism and TransportCompletedNCT05469204Phase 4
• Pharmacokinetic Interaction Between Ibuprofen and Acetaminophen, Tablets Administered Individually or in CombinationCompletedNCT05428306Phase 1
• Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion SurgeryCompletedNCT05413902Phase 4
• Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder SurgeryCompletedNCT05401916Not applicable
• The Effects of Acetaminophen on FearCompletedNCT05396677Not applicable
• Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination on Postoperative Opioid ConsumptionCompletedNCT05366777Not applicable

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