Vaginismus clinical trials
The registry lists 29 studies for Vaginismus across more than 10 countries. 9 are recruiting or about to start. 17 of them are mainly about Vaginismus (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Status
Who runs them
University of British Columbia (2) · Cairo University (2) · Medstar Health Research Institute (1) · Plastic Surgery Professional Association (1) · Faculdade de Ciências Médicas da Santa Casa de São Paulo (1) · Medipol University (1) · Imperial College London (1) · St. Olavs Hospital (1)
What is being tested here
Drugs under test in Vaginismus studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Botulinum toxin type A | 0 | 1 | 4 |
| Onabotulinum toxin A | 0 | 0 | 3 |
| Botulinum Toxins | 0 | 1 | 1 |
| Nifedipine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
Who these studies take
Of the 2 Vaginismus studies recruiting now, 2 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 2 (100%) are for women only and 0 (0%) for men only; 1 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 2 (100%) | 0 (0%) |
| 30 | 2 (100%) | 0 (0%) |
| 40 | 2 (100%) | 0 (0%) |
| 50 | 2 (100%) | 0 (0%) |
| 65 | 2 (100%) | 0 (0%) |
| 75 | 2 (100%) | 0 (0%) |
| 85 | 2 (100%) | 0 (0%) |
Across all 29 studies, recruiting or not: 48% stop at 75 or younger and 48% at 65; 14% take children; 90% are for women only and 0% for men only; 34% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Effect of Multimodal Physical Therapy on Vaginismus Secondary to Chronic ConstipationNov 9, 2026NCT07926399
Studies
Recruiting first, then most recently updated. Showing 29 of 29. search them.
- Effect of Multimodal Physical Therapy on Vaginismus Secondary to Chronic ConstipationNot yet recruitingNCT07926399Not applicable1 country
- Immersive Visual Modulation and Ambient Music Therapy During Transvaginal Ultrasonography in Women With VaginismusEnrolling by invitationNCT07734454Not applicable1 country
- Implementing Virtual Reality Exposure Therapy for Vaginismus: From Efficacy to Clinical Integration (VIVID 3)Not yet recruitingNCT07747298Not applicable1 country
- Measuring Pelvic Floor Muscle Fitness Before and After TreatmentNot yet recruitingNCT07605598Not applicable1 country
- VIBRating vs Traditional Therapy for Treatment of ENTry DyspareuniaRecruitingNCT06840314Not applicable1 country
- Effectiveness of Modern Physical Agents in the Treatment of Pelvic Floor DysfunctionsNot yet recruitingNCT06800222Not applicable1 country
- Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal WomenNot yet recruitingNCT06564883Phase 3
- Effect of Adding Interferential Current to Pelvic Floor Muscle Training on VaginismusNot yet recruitingNCT06486896Not applicable
- Photobiomodulation for Myofascial Pelvic PainRecruitingNCT05926752Not applicable1 country
- Virtual Reality Exposure for Vaginismus: A Replicated Single-Case DesignActive, not recruitingNCT06923306Not applicable1 country
- Effectiveness of Cognitive Behavioral Therapy on Psychological Distress and Problem-Solving Skills in Women With VaginismusCompletedNCT07588724Not applicable1 country
- Early Psychological Intervention After RapeActive, not recruitingNCT05489133Not applicable1 country
- Feasibility of Use of Vibrators With Vaginal Dilators for Vaginismus. (Vibrator Therapy and Dilators in Vaginismus)CompletedNCT04635345Not applicable1 country
- Pelvic Floor Physiotherapy Combined With Sexual Therapy in Vaginismus TreatmentCompletedNCT06760767Not applicable1 country
- Prospective on Market Patient-reported Outcomes for MilliActive, not recruitingNCT063978851 country
- Transperineal Ultrasound to Assess the Progress of LabourCompletedNCT024300381 country
- What is the Nature of Pelvic Floor Muscle Involvement in Dyspareunia?CompletedNCT042345551 country
- Trial of SVTampons vs Glass Vaginal Dilators in Treatment of VaginismusStatus unknownNCT05529407Not applicable1 country
- A Trial of Pelvic Floor Chemodenervation in Patients Undergoing Physical Therapy for High Tone Pelvic Floor DysfunctionCompletedNCT03199534Phase 41 country
- Spinal Anesthesia Facilitated Sexual Intercourse As A Treatment Option For VaginismusCompletedNCT04436172Not applicable
- Evaluation and Comparison of Women Pelvic Floor With and Without Sexual Dysfunction (Vaginismus)CompletedNCT03176069Not applicable1 country
- Electrolysis Technique vs Manual Therapy in Pelvic PainCompletedNCT03163160Not applicable1 country
- Botox Injection for Treatment of VaginismusCompletedNCT01352546Phase 11 country
- Injection of Botox in the Perineal Muscles in Resistant Cases of Vaginal SpasmCompletedNCT01859507Not applicable1 country
- A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic PainWithdrawnNCT01586286Not applicable1 country
- Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual PainStatus unknownNCT02022722Phase 41 country
- Childhood Sexual Abuse, Vaginismus and Labor DystociaStatus unknownNCT015301131 country
- Sexual Dysfunction and Dental CareCompletedNCT00281372
- Botulinum Toxin Injection for Treatment of VaginismusStatus unknownNCT00638066Phase 31 country