Trisomy 18 Syndrome clinical trials
The registry lists 28 studies for Trisomy 18 Syndrome across more than 10 countries. 2 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-10-29.
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Who runs them
Natera, Inc. (8) · Sequenom, Inc. (4) · Progenity, Inc. (3) · Women and Infants Hospital of Rhode Island (2) · CHU de Quebec-Universite Laval (1) · Premaitha Health (1) · Lenetix Medical Screening Laboratory (1) · Verinata Health, Inc. (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Nov 2027Hematological Profile in Children With Numerical Chromosomal Disorders · Assiut University
Who these studies take
Of the 1 Trisomy 18 Syndrome studies recruiting now, 1 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (100%) take children under 18. 1 (100%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (100%) | 0 (0%) |
| 18 | 1 (100%) | 0 (0%) |
| 30 | 1 (100%) | 0 (0%) |
| 40 | 1 (100%) | 0 (0%) |
| 50 | 1 (100%) | 0 (0%) |
| 65 | 1 (100%) | 0 (0%) |
| 75 | 1 (100%) | 0 (0%) |
| 85 | 1 (100%) | 0 (0%) |
Across all 28 studies, recruiting or not: 25% stop at 75 or younger and 25% at 65; 18% take children; 79% are for women only and 0% for men only; 46% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 28 of 28. search them.
- Hematological Profile in Children With Numerical Chromosomal DisordersNot yet recruitingNCT07807540
- The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk AssessmentRecruitingNCT076438961 country
- Verification of Risk Assignment for Whole Chromosome Using SNP-based NIPT in Vanishing Twin PregnanciesCompletedNCT050043371 country
- Evaluation of Fetal Bladder Emptying During the 11-14 Weeks' Ultrasound Examination as a Negative Predictive Marker for Chromosomal AbnormalitiesActive, not recruitingNCT071657431 country
- Prenatal Non-invasive Aneuploidy Test Utilizing SNPs TrialTerminatedNCT015456746 countries
- VAlidation of a Lower Cost aneUploidy scrEenCompletedNCT030873573 countries
- SNP-based Microdeletion and Aneuploidy RegisTry (SMART)CompletedNCT023814576 countries
- Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal BloodCompletedNCT018527083 countries
- Whole Blood Specimen Collection From Pregnant SubjectsStatus unknownNCT024305841 country
- Feasibility Study of a New Screening Program for Major Aneuploidies (T21, T18, T13) in the Emilia-Romagna Region (SAPERER)Status unknownNCT044379921 country
- Clinical Evaluation of the IONA Test for Non-invasive Pre Natal Screening in Twin PregnanciesCompletedNCT03200041Not applicable1 country
- Non-Invasive Chromosomal Evaluation of Trisomy StudyCompletedNCT022018621 country
- Multiple Gestation StudyCompletedNCT022785363 countries
- Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNACompletedNCT021097701 country
- Expanded Noninvasive Genomic Medical Assessment: The Enigma StudyCompletedNCT027874861 country
- High Risk Multiple Gestation StudyCompletedNCT022788741 country
- Study of Vanadis® NIPT for Non-invasive Prenatal Screening of Trisomies (T21, T18 and T13)Status unknownNCT035593741 country
- Non-Invasive Screening for Fetal AneuploidyStatus unknownNCT023179651 country
- Serum Sample Collection to Determine Analytical Performance Characteristics of the ADVIA Centaur PAPPA and BhCG AssaysCompletedNCT036297951 country
- Study of the Efficacy of New Non-invasive Prenatal Tests for Screening for Fetal Trisomies Using Maternal BloodCompletedNCT01925742Not applicable1 country
- Prenatal Screening for Down Syndrome With DNAFirstCompletedNCT019669911 country
- Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation PregnanciesTerminatedNCT022263151 country
- Comparison of Aneuploidy Risk EvaluationsCompletedNCT016633501 country
- Non-invasive Prenatal Diagnostic Validation StudyCompletedNCT015747811 country
- Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma MarkerCompletedNCT009713342 countries
- Non-Invasive Screening for Fetal AneuploidyCompletedNCT008479901 country
- Non-Invasive Screening for Fetal Aneuploidy: A New Maternal Plasma MarkerCompletedNCT007704581 country
- Non-Invasive Determination of Fetal Chromosome AbnormalitiesStatus unknownNCT008918521 country