Treatment Refusal clinical trials
The registry lists 28 studies for Treatment Refusal across 9 countries. 6 are recruiting or about to start. 10 of them are mainly about Treatment Refusal (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-30. Counting its 2 narrower conditions too, such as Vaccination Hesitancy: 189 studies, 21 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Sun Yat-sen University (2) · Case Western Reserve University (2) · Assistance Publique - Hôpitaux de Paris (2) · Hospital de Clinicas de Porto Alegre (1) · University Hospitals Cleveland Medical Center (1) · Florida State University (1) · Massachusetts General Hospital (1) · US Department of Veterans Affairs (1)
What is being tested here
Drugs under test in Treatment Refusal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Gemcitabine | 1 | 0 | 1 |
| Etoposide | 1 | 0 | 1 |
| Dexmedetomidine | 0 | 0 | 1 |
| Ketamine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026Patients' Refusal to Participate in Surgical Research: Prevalence, Attributed Factors, and How to Overcome · Mansoura University
- Jan 2027Assessment of Emotion Regulation Strategies Used When Suicidal · Ohio State University
- Feb 2027BrotherlyACT: A Tech-Enhanced Violence and Substance Use Intervention for Black Boys and Young Men · Rush University Medical Center
Who these studies take
Of the 5 Treatment Refusal studies recruiting now, 3 (60%) set no upper age limit and 1 (20%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 4 (80%) | 4 (80%) |
| 85 | 3 (60%) | 3 (60%) |
Across all 28 studies, recruiting or not: 32% stop at 75 or younger and 25% at 65; 21% take children; 11% are for women only and 4% for men only; 29% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 28 of 28. search them.
- Patients' Refusal to Participate in Surgical Research: Prevalence, Attributed Factors, and How to OvercomeRecruitingNCT078382851 country
- Assessment of Emotion Regulation Strategies Used When SuicidalRecruitingNCT05722197Not applicable1 country
- Effects of Italian Law 219/2017 in Pediatric Intensive Care UnitsNot yet recruitingNCT070930471 country
- Sociological Determinants of Positive Airway Pressure Adherence in OSA PatientsRecruitingNCT053853021 country
- PEG-ASP, Etoposide and Gemcitabine for Natural Killer/T LymphomaRecruitingNCT02705508Phase 21 country
- The Registry Study of Takayasu Arteritis in East ChinaRecruitingNCT038931361 country
- BrotherlyACT: A Tech-Enhanced Violence and Substance Use Intervention for Black Boys and Young MenActive, not recruitingNCT06359990Not applicable1 country
- Refusal to Participate in a Randomized Trial Involving Pregnancy and Childbirth: Factors Associated With Refusal and Reasons for Refusal and AcceptanceCompletedNCT066123201 country
- Facilitators and Barriers to Eptinezumab Administration in ThailandCompletedNCT070351971 country
- Culturally Aware AET Non-Initiation InterventionCompletedNCT05465408Not applicable1 country
- Women's Refusal to Participate in a Randomized Trial Involving First-trimester Screening for Pre-eclampsia: Factors Associated With Refusal and Reasons for Acceptance and RefusalCompletedNCT063227711 country
- Tailored Motivational Interviewing Implementation-Effectiveness Trial in Multidisciplinary Adolescent HIV Care SettingsCompletedNCT036819121 country
- Refusal of Organ Donation: a Study of Psychological, Anthropological and Cultural FactorsCompletedNCT063472891 country
- Psychoeducational Program for Cancer Patients.Active, not recruitingNCT06175195Not applicable1 country
- Weight Development in Children With Obesity After Declining TreatmentCompletedNCT058586971 country
- A Comparative Evaluation of Nebulized Dexmedetomidine and Nebulized Ketamine as a Premedication in Pediatric SurgeriesCompletedNCT05719506Phase 41 country
- Behavioral Economics Intervention to Increase Treatment Seeking in the National GuardStatus unknownNCT04098588Not applicable1 country
- Opposition to Diagnostic or Therapeutic Procedures by Aged Hospitalized PatientCompletedNCT033738381 country
- "Sandwich" Chemotherapy With Radiotherapy in Newly Diagnosed, Stage IE to IIE, ENKTLTerminatedNCT02520479Phase 21 country
- Endodontic Treatment of Necrotic Primary Teeth With Guedes Pinto Paste: A Randomized Clinical TrialCompletedNCT02216942Phase 31 country
- Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder PatientsCompletedNCT007635811 country
- Individual vs. Group Community Reinforcement Training to Help Parents of Substance-using Treatment-refusing YouthCompletedNCT01829789Not applicable1 country
- Improving Antipsychotic Adherence Among Patients With Serious Mental IllnessCompletedNCT00057135Not applicable1 country
- Customized Medication Adherence Enhancement for Adults With Bipolar DisorderCompletedNCT00830310Not applicable1 country
- Customized Medication Adherence Enhancement for Treating Adults With Bipolar DisorderCompletedNCT00763919Not applicable1 country
- Study of an Intervention to Improve Use of Life-saving Medications for Heart DiseaseCompletedNCT00323258Not applicable1 country
- Evaluation of Effectiveness of Pharmaceutical Care on the Adherence of HIV-Positive Patients to Antiretroviral TherapyCompletedNCT00959361Not applicable1 country
- Survey of Adherence to Immunosuppression and Other Medications in Kidney Transplant PatientsCompletedNCT004331341 country