Transsexualism clinical trials
The registry lists 54 studies for Transsexualism across more than 10 countries. 18 are recruiting or about to start. 29 of them are mainly about Transsexualism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
University Hospital, Ghent (4) · Central Hospital, Nancy, France (4) · University of Colorado, Denver (3) · St. Louis University (2) · Medical College of Wisconsin (2) · Unita Complessa di Ostetricia e Ginecologia (2) · University Ghent (2) · Universitätsklinikum Hamburg-Eppendorf (2)
What is being tested here
Drugs under test in Transsexualism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Estradiol | 0 | 0 | 3 |
| Testosterone | 0 | 0 | 3 |
| Testosterone 17 beta-cypionate | 0 | 0 | 2 |
| Dutasteride | 0 | 1 | 1 |
| Testosterone undecanoate | 0 | 0 | 1 |
| Cyproterone Acetate | 0 | 0 | 1 |
| Cyproterone | 0 | 0 | 1 |
Who these studies take
Of the 13 Transsexualism studies recruiting now, 8 (62%) set no upper age limit and 5 (38%) stop at 75 or younger. 2 (15%) take children under 18. 5 (38%) are for women only and 3 (23%) for men only; 7 (54%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 1 (8%) |
| 18 | 9 (69%) | 6 (46%) |
| 30 | 9 (69%) | 6 (46%) |
| 40 | 8 (62%) | 6 (46%) |
| 50 | 8 (62%) | 6 (46%) |
| 65 | 7 (54%) | 5 (38%) |
| 75 | 6 (46%) | 4 (31%) |
| 85 | 6 (46%) | 4 (31%) |
Across all 54 studies, recruiting or not: 43% stop at 75 or younger and 35% at 65; 15% take children; 35% are for women only and 13% for men only; 56% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Transsexualism studies take
Of 14 interventional studies with no phase under Transsexualism, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 24 mo5–36 · 14 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 54. Browse all 54 → or search them.
- Metoidioplasty and Phalloplasty Surgery Decision MakingEnrolling by invitationNCT06565663Not applicable1 country
- Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 VersionRecruitingNCT07092527Phase 41 country
- Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular SystemRecruitingNCT048382491 country
- Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINICRecruitingNCT042543541 country
- Prospective Imaging Assessment of Perineo-pelvic Static's Evolution After Sexual Reassignment Surgery in MtF Transgender Patient, by Peno-scrotal Inversion Vaginoplasty Technique (TRANSPELV)RecruitingNCT06093724Not applicable1 country
- Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning YouthRecruitingNCT045965921 country
- Puberty Suppression and Cardiometabolic HealthRecruitingNCT044823741 country
- Lower Urinary Tract Symptoms in Transmasculine Patients Undergoing Metoidioplasty and Their Acceptability of Pelvic Floor Muscle Training Assessed by a Pelvic, Obstetric and Gynaecological PhysiotherapistNot yet recruitingNCT06956989
- Feminizing Treatment in Transgender Women and Non-binary PersonsRecruitingNCT051697621 country
- Sexual Functioning After Erection Prosthesis Placement in Post Phalloplasty Transgender PersonsRecruitingNCT066397761 country
- Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender PatientsRecruitingNCT066397631 country
- Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.RecruitingNCT05883553Not applicable2 countries
- Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and ChondrolaryngoplastyRecruitingNCT06439290Not applicable1 country
- The Determinants of Fertility Preservation in TRANSgender Patients.RecruitingNCT060747961 country
- Sociological Study of the Life Courses of Young TRANSgender PatientsNot yet recruitingNCT06221163
- Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation PathwayNot yet recruitingNCT062184461 country
- Effect of Suture Material on Postoperative Nipple Areolar Complex WideningNot yet recruitingNCT06070324Not applicable
- Quality of Life of Transgender People - Implementation and Monitoring of an Online Cohort (e-QoL-Trans)RecruitingNCT057616781 country
- Cardiometabolic Health in Transgender MalesActive, not recruitingNCT049777651 country
- Androgen Effects on the Reproductive Neuroendocrine AxisTerminatedNCT06450405Phase 41 country
- An Education Initiative to Reduce Stigma Towards Sex Workers and Sexual Minorities Among Nursing StudentsCompletedNCT06434805Not applicable1 country
- Effect of Dose Fractionation of Testosterone Cypionate on Transgender Men with ErythrocytosisCompletedNCT05487794Not applicable1 country
- Transgender Estradiol Affirming TherapyCompletedNCT05010707Phase 21 country
- Drug-Drug Interaction Study in Trans Women Living With HIVActive, not recruitingNCT05663892Phase 41 country
- Effect of Hormone Therapy on Renal FunctionCompletedNCT044829201 country
- Is Bioimpedance Analysis Accurate in Transgender Males?CompletedNCT057288531 country
- Effect of Transgender Therapy on Muscle, Fat and Tissue ReceptorsTerminatedNCT045511441 country
- Effectiveness of Speech Therapy in Trans Women.CompletedNCT04708600Not applicable1 country
- Factors Associated With the Acne Severity Among Transmen Population: a Cross-sectional StudyCompletedNCT061490651 country
- Transgender Men's Perspectives on HIV Risk and HIV Prevention InterventionsCompletedNCT05666102Not applicable1 country
- Microeconomic Intervention to Reduce HIV Transmission in Economically Disadvantaged Transgender WomenTerminatedNCT04275310Not applicable1 country
- Safe Access for Bladder Entry in Transgender Men Following Penile ReconstructionCompletedNCT04454970Not applicable1 country
- HPV Prevalence in Transpersons - a Prospective StudyCompletedNCT04864951Not applicable2 countries
- Coagulation and Fibrinolysis of Estradiol in TranswomenTerminatedNCT05387577Early Phase 11 country
- i2TransHealth: Interdisciplinary, Internet-based Trans Health CareCompletedNCT04290286Not applicable1 country
- Expectations and Beliefs of Transgender People Regarding Hormonal TreatmentStatus unknownNCT054747681 country
- Extracellular Vesicles and Endothelial Function in Transgender SubjectsStatus unknownNCT04971447Not applicable
- Use of an External Erectile Device in Transgender Man Following PhalloplastyCompletedNCT03823014Not applicable1 country
- Evaluation of an Adaptative, Multidisciplinary, Reach-out Program, Facilitating Pre Exposition HIV Prophylaxis (PrEP) Prescription and Retention in Care, in a Group of Trans Womens (TW) at High Risk of HIV Infection.Status unknownNCT05415930
- GEnder Dysphoria Treatment in SwedenCompletedNCT025180091 country
- Reducing Transphobia Among Adolescents Through a Brief Video InterventionCompletedNCT04969003Not applicable1 country
- Family Relationships and Nutrition in TGGD Youth and Young AdultsCompletedNCT051638601 country
- Transgender Cohort Study of Gender Affirmation and HIV-related HealthStatus unknownNCT035959561 country
- Effects of Testosterone Plus Dutasteride or Placebo on Muscle Strength, Body Composition and Metabolism in TransmenCompletedNCT04545450Phase 3
- Supporting Trans Identities and Occupational Justice Through Narrative Informed Theatre: Supporting Trans Identities and Occupational Justice Through Narrative Informed TheatreCompletedNCT04515654Not applicable1 country
- Implementing HPV DNA Self-Collection to Increase Rates of Cervical Cancer Screening in Transgender MenStatus unknownNCT04154358Not applicable
- Observational Study on Metabolism and Psychopathology in Transsexual PatientsCompletedNCT021852741 country
- TransCare - Genital Surgery for Trans Women in Centralized vs. Decentralized Health Care Delivery SettingsStatus unknownNCT038726481 country
- Sexuality in Transmen During Hormone and Operative TreatmentStatus unknownNCT036379201 country
- Testosterone and Its Metabolites in GIDCompletedNCT00146146Phase 31 country