Testicular Germ Cell Tumor clinical trials
The registry lists 85 studies for Testicular Germ Cell Tumor across more than 10 countries. 10 are recruiting or about to start. 26 of them are mainly about Testicular Germ Cell Tumor (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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· Enrollment: 300 → 450 participants
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Who runs them
Memorial Sloan Kettering Cancer Center (10) · Fred Hutchinson Cancer Center (5) · Medical Research Council (5) · European Organisation for Research and Treatment of Cancer - EORTC (4) · UNICANCER (3) · Royal Marsden NHS Foundation Trust (3) · Eastern Cooperative Oncology Group (3) · Case Comprehensive Cancer Center (2)
What is being tested here
Drugs under test in Testicular Germ Cell Tumor studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ifosfamide | 0 | 2 | 11 |
| Paclitaxel | 0 | 3 | 9 |
| Carboplatin | 0 | 1 | 9 |
| Etoposide | 0 | 2 | 9 |
| Cisplatin | 0 | 1 | 5 |
| Cyclophosphamide | 0 | 0 | 3 |
| Gemcitabine | 0 | 0 | 2 |
| Pegfilgrastim | 0 | 0 | 2 |
| Filgrastim | 0 | 0 | 2 |
| Granisetron | 0 | 1 | 2 |
Drug classes tested here Alkylating agents 17 · Antimitotic agents 11 · Corticosteroids 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors · HiFiBiO Therapeutics
- Oct 2027Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE) · National Cancer Institute (NCI)
Who these studies take
Of the 7 Testicular Germ Cell Tumor studies recruiting now, 4 (57%) set no upper age limit and 2 (29%) stop at 75 or younger. 2 (29%) take children under 18. 0 (0%) are for women only and 4 (57%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (43%) | 7 (100%) |
| 30 | 3 (43%) | 7 (100%) |
| 40 | 3 (43%) | 7 (100%) |
| 50 | 2 (29%) | 6 (86%) |
| 65 | 2 (29%) | 5 (71%) |
| 75 | 2 (29%) | 5 (71%) |
| 85 | 2 (29%) | 5 (71%) |
Across all 85 studies, recruiting or not: 25% stop at 75 or younger and 20% at 65; 48% take children; 0% are for women only and 38% for men only; 1% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 85. Browse all 85 → or search them.
- Medical Access Program for DS-9606a (DS-9606) in Patients With Advanced Testicular Germ Cell TumorsAvailableNCT07863284
- Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid TumorsRecruitingNCT06276491Phase 16 countries
- Effect of Hypnosis in the Management of Anxiety and Chemo-induced Symptoms in Adolescents and Young Adults With Sarcoma or Germ Cell Tumor and in Young Women With Breast CancerRecruitingNCT07614620Not applicable1 country
- Sentinel Node Identification Using Gamma and Near-Infrared Imaging in TesticulAr MaLignanciesRecruitingNCT077778871 country
- Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)RecruitingNCT06041503Phase 21 country
- Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of CareNot yet recruitingNCT07699640Not applicable2 countries
- A Prospective Study to Evaluate miRNA371 and Outcomes in Patients With Newly Diagnosed Germ Cell TumorsRecruitingNCT074530821 country
- Sentinel Lymph Node Biopsy in Stage AI-IIA Germ Cell TumorsRecruitingNCT06133699Not applicable1 country
- Follow-up After Surgery for Testicular CancerRecruitingNCT056709381 country
- Sentinel Lymph Node Procedure in Testicular Germ Cell TumourNot yet recruitingNCT03448822
- Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid TumorsTerminatedNCT00788125Phase 1/21 country
- A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid TumorsActive, not recruitingNCT05238883Phase 12 countries
- Role of Axumin PET Scan in Germ Cell TumorCompletedNCT034268651 country
- A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From SpermWithdrawnNCT06940804Phase 2
- Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell TumorsCompletedNCT00104676Phase 33 countries
- Milademetan in Advanced/Metastatic Solid TumorsTerminatedNCT05012397Phase 21 country
- Exercise in Testicular Germ Cell Cancer SurvivorsActive, not recruitingNCT05063760Not applicable1 country
- Diagnostic Study of Patients With Stage I Testicular CancerCompletedNCT00003800Not applicable1 country
- Paclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell TumorsCompletedNCT00003518Phase 22 countries
- Physician-Initiated Stop-Smoking Program for Patients Receiving Treatment for Early-Stage CancerCompletedNCT00002520Not applicable1 country
- Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell TumorsCompletedNCT00002566Phase 31 country
- Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell TumorsCompletedNCT02429466Phase 11 country
- Study of Cisplatin-Induced Peripheral Neuropathy in Patients With Germ Cell TumorCompletedNCT026777271 country
- Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid TumorsCompletedNCT00007813Phase 11 country
- T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell TransplantTerminatedNCT006517161 country
- Exploratory Study of Molecular Characterization in Patients With Metastatic Germ Cell Tumours Refractory/Resistant to Platinum TreatmentStatus unknownNCT039805871 country
- Carboplatin, Etoposide, Cyclophosphamide, and Autologous Bone Marrow Transplantation in Patients With Relapsed or Refractory CancerCompletedNCT00002943Phase 21 country
- A Case-control Study to Assess the Association Between Environmental, Domestic and Occupational Exposures and the Risk of Testicular Germ Cell TumorCompletedNCT021099261 country
- Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell TumorsCompletedNCT00470366Phase 21 country
- Blood Samples From Patients on a Clinical Trial to CINV During HSCTTerminatedNCT009000681 country
- Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell TransplantTerminatedNCT00324324Phase 31 country
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell CancerCompletedNCT00002931Phase 21 country
- Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic SyndromeTerminatedNCT00946283Not applicable1 country
- High-dose ICE With AmifostineCompletedNCT00003657Phase 21 country
- Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell TumorsTerminatedNCT00072215Phase 32 countries
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell TumorsTerminatedNCT00003852Phase 21 country
- Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell TumorsCompletedNCT00002558Phase 1/21 country
- Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to CisplatinCompletedNCT00423852Phase 1/21 country
- Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor ProgressionCompletedNCT01433224
- Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell TransplantCompletedNCT00293384Not applicable1 country
- Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With SurgeryWithdrawnNCT00006126Phase 1
- Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to TreatmentCompletedNCT00453310Phase 21 country
- Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic CancerTerminatedNCT008991321 country
- Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell TransplantTerminatedNCT010774401 country
- Interleukin-12 in Treating Patients With Hematologic Cancers or Solid TumorsCompletedNCT00003107Phase 11 country
- Vaccine Therapy in Treating Patients With Advanced or Metastatic CancerCompletedNCT00027534Phase 11 country
- Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular CancerCompletedNCT00004077Phase 21 country
- Positron Emission Tomography in Detecting Testicle CancerCompletedNCT00045045Not applicable1 country
- Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular CancerCompletedNCT00003014Phase 37 countries
- CT Scans in Treating Patients With Stage I Testicular Cancer After Undergoing OrchiectomyCompletedNCT00003420Not applicable1 country