Telangiectasia, Hereditary Hemorrhagic: all 102 studies

Page 1 of 2. Open to participants first (24), then studies with results posted, then the rest; newest registration first within each.

• Prevalence of Obstructive Sleep Apnea in HHT and HHT-specific Challenges in OSA-therapy - a Retrospective Cohort StudyNot yet recruitingNCT07886632
• Phase 1b Study of TX002100 in Participants With Hematologic Support-Dependent Hereditary Hemorrhagic Telangiectasia (HHT)Not yet recruitingNCT07863609Phase 1
• Body Donation in HHTRecruitingNCT07826845Not applicable
• A Trial to Assess the Efficacy and Safety of Engasertib in Participants With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT)RecruitingNCT07743671Phase 3
• Topical TOR-582 Treatment of Epistaxis in HHTNot yet recruitingNCT07667413Phase 1
• DIAG723 in Adults With Hereditary Hemorrhagic TelangiectasiaRecruitingNCT07623525Phase 1/2
• Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)RecruitingNCT07601425Phase 1/2
• Quality of Life in Pediatric Participants With HHTRecruitingNCT07474428
• Efficacy and Tolerance of Treatment With Bevacizumab for Severe Liver Involvement With High Cardiac Output in Hereditary Hemorrhagic Telangiectasia Within the French Hereditary Hemorrhagic Telangiectasia NetworkEnrolling by invitationNCT07445347
• Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound DeviceRecruitingNCT07414446Not applicable
• Immunological Effects of Iron Supplementation in HHT DiseaseRecruitingNCT07111598Not applicable
• Cardiac Evaluation in Hereditary Hemorrhagic TelangiectasiaNot yet recruitingNCT07101575
• Institutional Registry of Rare DiseasesRecruitingNCT06573723
• Quality of Life in Patients With Hemorrhagic TelangiectasiaEnrolling by invitationNCT06261333
• Comprehensive HHT Outcomes Registry of the United States (CHORUS)RecruitingNCT06259292
• Prospective Study of Antiplatelet and Anticoagulation Therapy in Hereditary Haemorrhagic TelangiectasiaRecruitingNCT05641142Not applicable
• Calcium-phosphate Complications Induced by IV Iron Supplementation in Patients With Rendu-Osler DiseaseRecruitingNCT05544669
• Efficacy of Nintedanib for Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) PatientsRecruitingNCT04976036Phase 2
• Influence of Hypoxic Induced Factors in Patients With Hereditary Hemorrhagic TelangiectasiaRecruitingNCT04469517
• Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 StudyRecruitingNCT04194619
• Pazopanib for the Treatment of Epistaxis in Hereditary Hemorrhagic TelangiectasiaNot yet recruitingNCT03850730Phase 1/2
• Institutional Registry of Haemorrhagic Hereditary TelangiectasiaRecruitingNCT01761981
• Case Notes Review on Patients With Hereditary Haemorrhagic TelangiectasiaRecruitingNCT00230685
• Molecular Studies on Hereditary Haemorrhagic Telangiectasia FamiliesRecruitingNCT00230620
• Sirolimus for Nosebleeds in HHTCompletedNCT05269849Phase 2Results posted
• Timolol Gel for Epistaxis in Hereditary Hemorrhagic TelangiectasiaCompletedNCT04139018Phase 2Results posted
• Pomalidomide for the Treatment of Bleeding in HHTCompletedNCT03910244Phase 2Results posted
• Prospective Pilot Study of Floseal for the Treatment of Anterior Epistaxis in Patients With (HHT)CompletedNCT02638012Not applicableResults posted
• Intranasal Bevacizumab for HHT-Related EpistaxisCompletedNCT02389959Phase 4Results posted
• Evaluation of Pazopanib on Bleeding in Subjects With Hereditary Haemorrhagic TelangiectasiaTerminatedNCT02204371Phase 2Results posted
• Topical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of ConceptCompletedNCT01752049Phase 1/2Results posted
• Diet and Hereditary Haemorrhagic TelangiectasiaCompletedNCT01692015Not applicableResults posted
• Hereditary Haemorrhagic Telangiectasia Flight Safety StudyCompletedNCT01590121Results posted
• Office-sclerotherapy for Epistaxis Due to Hereditary Hemorrhagic TelangiectasiaCompletedNCT01408732Phase 1/2Results posted
• North American Study of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT01408030Phase 2Results posted
• Submucosal Bevacizumab for the Management of Recurrent Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT01402531Phase 2Results posted
• Topical Bevacizumab for the Management of Recurrent Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT01397695Phase 2Results posted
• Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic TelangiectasiaTerminatedNCT00588146Phase 2Results posted
• IV Bevacizumab Treatment of Patients With Hereditary Hemorrhagic Telangiectasia (HHT) or Rendu-Osler (RO) Disease: A Retrospective Analysis of French Cohort Data From 2009 to 2024CompletedNCT07772050
• A Trial of TER-1754 in Patients With Hereditary Hemorrhagic TelangiectasiaWithdrawnNCT07255846Phase 1
• Description of the Impact of Symptoms on Quality of Life in HHT Disease: DISQUOCompletedNCT07191639
• Pomalidomide for the Treatment of Bleeding in Hereditary Hemorrhagic Telangiectasia Longitudinal Assessment StudyCompletedNCT07018401
• A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)Active, not recruitingNCT06659640Phase 1/2
• Stress-Echography in Hereditary Haemorrhagic Telangiectasia Patient With Hepatic InvolvementCompletedNCT05954481Not applicable
• Hereditary Hemorrhagic Telangiectasia and Neurovascular Manifestations, in the Danish HHT DatabaseActive, not recruitingNCT05933330
• Counseling Intervention in Hereditary Hemorrhagic Telangiectasia in the COVID Era.CompletedNCT05752253Not applicable
• Genotype Expression and Phenotype of Endothelial Cells, Carrying an ACVRL1, ENG or SMAD4 Mutation, in Response to BMP9 for the Identification of New Therapeutic Targets in Hereditary Haemorrhagic TelangiectasiaCompletedNCT05632484Not applicable
• Genotype-phenotype Association in Hereditary Hemorrhagic TelangiectasiaCompletedNCT05550376
• Assess Safety and Efficacy of VAD044 in HHT PatientsActive, not recruitingNCT05406362Phase 1/2
• Ultra-low-dose Chest CT for HHTCompletedNCT04874558
• Tacrolimus Trial for Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT04646356Phase 2
• Bevacizumab In Hereditary Hemorrhagic TelangiectasiaActive, not recruitingNCT04404881Phase 2
• CHORUS - Comprehensive HHT Outcomes Registry of the United States (Formerly OUR HHT Registry)Active, not recruitingNCT04150822
• Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia PatientsTerminatedNCT04113187Phase 3
• Diagnostic Value of Ultra-low Dose Thoracic Scanner for the Pulmonary Arteriovenous Malformation Detection in HHT PatientCompletedNCT04108052Not applicable
• Vitamin D and Hereditary Haemorrhagic TelangiectasiaStatus unknownNCT03981562Phase 2
• Efficacy of Nintedanib Per os as a Treatment for Epistaxis in HHT Disease.CompletedNCT03954782Phase 2
• Recurrence of Hereditary Hemorrhagic Telangiectasia (HHT) After Liver TransplantationCompletedNCT03942315
• Pulmonary Arteriovenous Malformations (PAVMs) in Hereditary Haemorrhagic Telangiectasia (HHT)CompletedNCT03940014
• Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz)Active, not recruitingNCT03850964Phase 2/3
• Evaluation of Video-assisted Instructions of Nasal Self-packing in Patients with HHTActive, not recruitingNCT03841422
• Development of a Quality of Life Measurement Scale in Hereditary Haemorrhagic Telangiectasia (HHT) Disease.CompletedNCT03695874
• Evaluation of Obstetrical and Neonatal Complications in Hereditary Haemorrhagic Telangiectasia (HHT)CompletedNCT03691142
• Prospective Descriptive Study of the Angiogenic T Cell Population in Subjects With Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT03572556
• Nationwide Awareness Campaign and Call for Dental Screening for HHT in GermanyStatus unknownNCT03549949
• Doxycycline for Hereditary Hemorrhagic TelangiectasiaCompletedNCT03397004Phase 2
• BABH Study: Efficacy and Safety of Bevacizumab on Severe Bleedings Associated With Hemorrhagic Hereditary Telangiectasia (HHT).CompletedNCT03227263Phase 3
• Immunmodulation in Patients With HHTCompletedNCT02983253
• MRA With Feraheme in HHTCompletedNCT02977637Phase 1
• Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHTStatus unknownNCT02963129Phase 3
• Graded TTCE for Post-Embolization PAVM MonitoringCompletedNCT02936349
• Octreotide in Patients With GI Bleeding Due to Rendu-Osler-WeberStatus unknownNCT02874326Phase 2
• Symptoms and Treatment Results in Hereditary Hemorrhagic TelangiectasiaCompletedNCT02690246
• Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)CompletedNCT02484716Phase 2
• Frequency of Common Medical Conditions in People With and Without HHTCompletedNCT02464644Not applicable
• Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs With and Without Airflow ObstructionStatus unknownNCT02458703Not applicable
• Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMsCompletedNCT02436213Not applicable
• Pomalidomide in Hereditary Hemorrhagic Telangiectasia and Transfusion-Dependent Vascular Ectasia: a Phase I StudyCompletedNCT02287558Phase 1
• Treatment of Hereditary Hemorrhagic Telangiectasia of the Nasal Mucosa by Intranasal Bevacizumab : Search for Effective DoseCompletedNCT02157987Phase 1/2
• Efficacy of a Bevacizumab Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)TerminatedNCT02106520Phase 2/3
• At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsCompletedNCT01931644
• Iron Deficiency and Hereditary Haemorrhagic TelangiectasiaTerminatedNCT01908543Not applicable
• The ELLIPSE Study: A Phase-1 Study Evaluating the Tolerance of Bevacizumab Nasal Spray to Treat Epistaxis in Hereditary Hemorrhagic TelangiectasiaCompletedNCT01507480Phase 1
• Efficacy of Thalidomide in the Treatment of Hereditary Hemorrhagic TelangiectasiaCompletedNCT01485224Phase 2
• Ranibizumab for the Management of Recurrent Nosebleeds in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)WithdrawnNCT01406639Phase 1
• Intranasal Submucosal Bevacizumab for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT01314274Phase 2
• Cerebral Hemorrhage Risk in Hereditary Hemorrhagic TelangiectasiaCompletedNCT01158807
• Tranexamic Acid and Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)CompletedNCT01031992Phase 3
• Efficacy and Safety of Bevacizumab for the Treatment Hemorrhagic Hereditary Telangiectasia (HHT) Associated With Severe Hepatic Vascular Malformations. Phase II StudyCompletedNCT00843440Phase 2
• Study of Histological Samples From Patients With Hereditary Haemorrhagic TelangiectasiaCompletedNCT00733655
• Study of Endothelial Cells in Patients With Hereditary Haemorrhagic TelangiectasiaWithdrawnNCT00733629
• Screening Behavior in Adults With Hereditary Hemorrhagic TelangiectasiaCompletedNCT00684879
• Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal BleedingCompletedNCT00389935Phase 2
• Anti-Estrogen Therapy for Hereditary Hemorrhagic Telangiectasia A Double-Blind Placebo-Controlled Clinical TrialCompletedNCT00375622Phase 2
• ATERO : A Randomised Study With Tranexamic Acid in Epistaxis of Rendu Osler SyndromeCompletedNCT00355108Phase 3
• Investigation of Plasma Proteins in Patients With Hereditary Haemorrhagic Telangiectasia and PAVMsCompletedNCT00230672
• Investigation of Coagulation Parameters in Hereditary Haemorrhagic TelangiectasiaCompletedNCT00230659
• Studies of White Blood Cells Derived From HHT PatientsActive, not recruitingNCT00230633
• Phase III Randomized, Placebo-Controlled, Crossover Study of Soy Protein Isolate for Hereditary Hemorrhagic TelangiectasiaCompletedNCT00004654Phase 3
• Study of the Natural History and Genotype-Phenotype Correlations of Hereditary Hemorrhagic Telangiectasia PatientsCompletedNCT00004649

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