An observational study in Hereditary Haemorrhagic Telangiectasia (HHT), sponsored by University Hospital, Essen. Completed at 1 site in Germany. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-12-20.
Sponsored by University Hospital, Essen · Observational
Hereditary haemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, is an inherited multisystemic disorder. Literature suggests that HHT is often associated with higher frequency of infectious diseases.
The purpose of this study is to evaluate a variety of immunologic parameters in the blood serum of HHT patients in comparison to probands.
Hereditary haemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, is an inherited multisystemic disorder with recurrent epistaxis, mucocutaneous telangiectasia and visceral arteriovenous malformations. Literature and the investigators' observation suggest that HHT is often associated with higher frequency of infectious diseases. This might be a hint for a immunocompromised situation.
The purpose of this study is to evaluate a variety of immunologic parameters in the blood serum of HHT patients in comparison to probands.
102 studies on the registry are indexed under Telangiectasia, Hereditary Hemorrhagic; 24 are open to participants now.
This study's enrollment of 124 is below the median of 207 across 39 observational studies indexed under Telangiectasia, Hereditary Hemorrhagic.
Browse Telangiectasia, Hereditary Hemorrhagic studies →University Hospital, Essen is the lead sponsor of 116 studies on the registry; 33 are open to participants now.
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Inclusion Criteria: Aged 18 or over, HHT,
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Exclusion Criteria:
blood sample of patients with HHT
Other: blood sample
blood sample of healthy controls
Other: blood sample
none, only laboratory tests on blood serum
Amounts of leucocytes in patients with HHT
Time frame: November 2016 - December 2018
Differences in distribution of leucocytes in patients with HHT
Time frame: November 2016 - December 2018
Functional properties of leucocytes in patients with HHT
Time frame: November 2016 - December 2018
Differences in size of leucocytes in patients with HHT
Time frame: November 2016 - December 2018
Plan to share: Undecided
No publications or documents are linked to this record.
The record gives a start of Jun 2016, a primary completion of Oct 2019 and a completion of Oct 2019. It does not say whether these dates are actual or estimated.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2019. You cannot join it, but the record below documents what was studied.
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Telangiectasia, Hereditary Hemorrhagic →