Spastic Paraplegia, Hereditary: all 51 studies
Page 1 of 1. Open to participants first (20), then studies with results posted, then the rest; newest registration first within each.
- Non-invasive Spinal Stimulation for Gait in Genetic SpasticityEnrolling by invitationNCT07930481Not applicable
- Rare Disease Registry Database for Movement Disorders in Southern Anhui ProvinceRecruitingNCT07838883
- TreatHSP Platform: Adaptive Natural History Platform for Ataxias, HSPs, and Spastic AtaxiasRecruitingNCT07798674
- 12-Week Strength and Functional Exercise Program for Hereditary Spastic Paraplegia Trial (HSPMOVE)Enrolling by invitationNCT07561359Not applicable
- Neuromodulation to Enhance Motor Function in HSPRecruitingNCT07417943Not applicable
- Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic PathologyRecruitingNCT07136844Not applicable
- The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in ChildrenRecruitingNCT07090057Not applicable
- Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47)Not yet recruitingNCT06948019Phase 1/2
- A Prospective Cohort Study of Surgical Treatment for Foot Deformities in HSPRecruitingNCT06936163
- A Prospective Cohort Study of ITB Treatment for HSPRecruitingNCT06844734
- Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)RecruitingNCT06728787
- STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic StrategiesRecruitingNCT06572046
- Spastic Paraplegia - Centers of Excellence Research NetworkRecruitingNCT06553976
- Calcium Folinate Treatment of Spastic Paraplegia 56RecruitingNCT06478238Early Phase 1
- Evaluation of an Intensive Training Program for Patients with Hereditary Spastic Paraparesis SPG4/SpastRecruitingNCT06229626Not applicable
- Natural History Study of Patients with HPDL MutationsRecruitingNCT05848271
- Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)RecruitingNCT05354622
- Registry and Natural History Study for Early Onset Hereditary Spastic ParaplegiaRecruitingNCT04712812
- Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related DisordersRecruitingNCT03981276
- The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4RecruitingNCT03206190Not applicable
- Single and Multiple Ascending Dose Study of MTR-601 in Healthy IndividualsCompletedNCT06117020Phase 1Results posted
- A Study to Evaluate Administration of SBT101 Gene Therapy in Adult Patients With Adrenomyeloneuropathy (AMN)TerminatedNCT05394064Phase 1/2Results posted
- Repetitive Transcranial Magnetic Stimulation as Therapy in Hereditary Spastic Paraplegia and AdrenomyeloneuropathyCompletedNCT03627416Not applicableResults posted
- Dental-Oral and Craniofacial Characteristics of Hereditary Spastic Paraplegia: A Preliminary StudyCompletedNCT07799233
- D-Cycloserine for Serine Palmitoyltransferase InhibitionCompletedNCT07542548Phase 4
- Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular DiseaseActive, not recruitingNCT07478172Not applicable
- Flexibility, Resistance, Aerobic, Movement Execution Training in Adults With Hereditary Spastic ParaplegiaActive, not recruitingNCT06742697Not applicable
- Enhancement of Quality of Work And LifeActive, not recruitingNCT06573866Not applicable
- Assessment of the Psychophysical State During Rehabilitation Treatment With LokomatCompletedNCT05767268
- Effect of Dalfampridine in Patients With Hereditary Spastic ParaplegiaCompletedNCT05613114Not applicable
- A Pilot Study of Shockwave Therapy in HSPWithdrawnNCT05411627Not applicable
- Identification of Modifying Factors in Hereditary Spastic ParaplegiaCompletedNCT05373082
- Spinal Cord Stimulation Therapy for Hereditary Spastic Paraplegias PatientsStatus unknownNCT05196178Not applicable
- Imaging Biomarkers in Spastic Paraplegia Type 5CompletedNCT05174403
- Study of Disease Progression in Adults With Inherited Forms of Spastic ParaplegiaTerminatedNCT05008874
- Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11)CompletedNCT04912609
- Phenotype, Genotype and Biomarkers 2Active, not recruitingNCT04875416
- Testing Miglustat Administration in Subjects With Spastic Paraplegia 11CompletedNCT04768166Phase 2
- SNAP: Measurement of the Subjective Perception of the Symptom in Hereditary Spastic Paraparesis (HSP)CompletedNCT04256681Not applicable
- Improving Gait Adaptability in Hereditary Spastic ParaplegiaCompletedNCT04180098Not applicable
- PCSK9 Inhibitor Treatment for Patients With SPG5Status unknownNCT04101643Phase 1/2
- Physiotherapy in Hereditary Spastic ParaplegiaCompletedNCT03961906Phase 2
- Studying Cognition in SPG4CompletedNCT03104088
- Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31TerminatedNCT02859428
- A Patient Centric Motor Neuron Disease Activities of Daily Living ScaleCompletedNCT02852278
- Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic ParaplegiaCompletedNCT02604186Phase 2/3
- Phenotype, Genotype & Biomarkers in ALS and Related DisordersActive, not recruitingNCT02327845
- Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5CompletedNCT02314208Phase 2
- Genetic and Physical Study of Childhood Nerve and Muscle DisordersCompletedNCT01568658
- Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00677768
- Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral SclerosisCompletedNCT00023075