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CompletedNCT05055947Updated Jan 25, 2022

Efficacy Biomarker Investigation on Extensive Stage Small Cell Lung Cancer

An observational study in Extensive Stage Small Cell Lung Cancer, sponsored by Hunan Province Tumor Hospital. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-01-25.

Sponsored by Hunan Province Tumor Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
60
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of the trial is to find some biomarkers to predict the efficacy of Atezolizumab plus etoposide and platinum based chemotherapy as the first line treatment in extensive stage small cell lung cancer. Mainly observe the patient's progression free survival time after treatment.

02

Conditions studied

  • Extensive Stage Small Cell Lung Cancer
03

In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's enrollment of 60 is below the median of 189 across 1,514 observational studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Hunan Province Tumor Hospital is the lead sponsor of 72 studies on the registry; 47 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Extensive Stage Small Cell Lung Cancer who Treated with Atezolizumab plus Etoposide and Platinum Based Chemotherapy

Inclusion criteria

  • 18, Extensive Stage Small Cell Lung Cancer Confirmed by Histopathology Treated with Atezolizumab plus Etoposide and Platinum Based Chemotherapy

Exclusion criteria

Exclusion Criteria:

  • Patients with contraindication of chemotherapy Pregnant or breast feeding women
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
60 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Interventions

  • DrugFirst line EC/EP+Atezolizumab

    Etoposide (100mg/㎡) Carboplatin (AUC=4) Atezolizumab(1200mg) ivgtt, every 21 days

06

What researchers measure

Primary outcomes

  1. PFS

    Progression free survival

    Time frame: April 2019- July 2021

  2. OS

    Overall survival

    Time frame: April 2019- July 2021

07

Study locations

1 site
  • Hunan Cancer Hospital
    Changsha, Hunan 410013, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 25, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05055947
Lead sponsor
Hunan Province Tumor Hospital
Responsible party
Yongchang Zhang (HunanPTH, Hunan Province Tumor Hospital) — Principal investigator
First posted
Sep 24, 2021
Start date
Apr 1, 2019
Primary completion
Jul 1, 2021
Completion
Sep 14, 2021
Last update
Jan 25, 2022

Study contacts

Yongchang Zhang, MD
principal investigator · Hunan Cancer Hospital

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.

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