Severe Dengue clinical trials
The registry lists 65 studies for Severe Dengue across more than 10 countries. 5 are recruiting or about to start. 51 of them are mainly about Severe Dengue (how this is decided). Per ClinicalTrials.gov, last updated 2026-08-06.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Sanofi Pasteur, a Sanofi Company (25) · National Institute of Allergy and Infectious Diseases (NIAID) (13) · Sanofi (4) · U.S. Army Medical Research and Development Command (3) · National University Hospital, Singapore (2) · University of the Philippines (2) · Oxford University Clinical Research Unit, Vietnam (2) · Mahidol University (1)
What is being tested here
Drugs under test in Severe Dengue studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone (DengDex Study) · Chulalongkorn University
- Dec 2026Innovative Multidisciplinary Strategies for Combating Severe Dengue · Karolinska Institutet
- Jan 2027Gut Leakage' in Dengue · University of Oxford
Who these studies take
Of the 4 Severe Dengue studies recruiting now, 2 (50%) set no upper age limit and 1 (25%) stop at 75 or younger. 2 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (50%) | 2 (50%) |
| 18 | 4 (100%) | 4 (100%) |
| 30 | 3 (75%) | 3 (75%) |
| 40 | 3 (75%) | 3 (75%) |
| 50 | 3 (75%) | 3 (75%) |
| 65 | 3 (75%) | 3 (75%) |
| 75 | 3 (75%) | 3 (75%) |
| 85 | 3 (75%) | 3 (75%) |
Across all 65 studies, recruiting or not: 82% stop at 75 or younger and 80% at 65; 52% take children; 2% are for women only and 0% for men only; 75% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Severe Dengue studies take
Of 13 phase 2 interventional studies under Severe Dengue, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 24 mo20–47 · 13 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 65. Browse all 65 → or search them.
- Gut Leakage' in DengueRecruitingNCT076029201 country
- Efficacy of Dengue Infection With Warning Signs Treated With Dexamethasone (DengDex Study)RecruitingNCT05631405Not applicable1 country
- Therapeutics for Moderate and Severe DengueNot yet recruitingNCT07543458Phase 310 countries
- Innovative Multidisciplinary Strategies for Combating Severe DengueRecruitingNCT067518362 countries
- NT-proBNP and Troponin I in Dengue ChildrenRecruitingNCT048374301 country
- Severe Dengue in Critical Care at Villavicencio, Colombia.CompletedNCT059386471 country
- Anakinra in Dengue With Hyperinflammation ( AnaDen )Active, not recruitingNCT05611710Phase 21 country
- Evaluating Public Awareness and Preventive Actions for Dengue Fever in Sudan Amidst Ongoing CrisesCompletedNCT072058481 country
- The Comparative Efficacy of Standard Treatment Plus Ribavirin vs Standard Treatment Alone in Preventing Clinically Significant Hemorrhage in Patients With Dengue FeverCompletedNCT06744777Phase 31 country
- Clinical and Laboratory Factors for the Progression of Severe Dengue Among Hospitalized Patients During an UpsurgeCompletedNCT066970411 country
- Efficacy of Fresh Frozen Plasma (FFP) in Treating Thrombocytopenia in Dengue PatientsActive, not recruitingNCT06642493Not applicable1 country
- Cohort Event Monitoring for Dengvaxia®, CYD-TDV Dengue VaccineCompletedNCT02948933
- Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive AdultsCompletedNCT02741128Phase 21 country
- Effect of Montelukast in Preventing Dengue With Warning Signs in Dengue PatientsCompletedNCT04673422Phase 2/31 country
- Dengue Serostatus Study in the PhilippinesActive, not recruitingNCT03465254
- Dengue Effectiveness Study in the PhilippinesCompletedNCT038036181 country
- Cohort of Patients Infected by an ArbovirusStatus unknownNCT010998525 countries
- Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 YearsCompletedNCT00788151Phase 21 country
- Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy SubjectsCompletedNCT00875524Phase 21 country
- Efficacy and Safety of Dengue Vaccine in Healthy ChildrenCompletedNCT00842530Phase 21 country
- Study of a Tetravalent Dengue Vaccine in Healthy Adult Subjects Aged 18 to 45 Years in IndiaCompletedNCT01550289Phase 21 country
- Long-Term Study of Hospitalized Dengue & Safety in Thai Children Included in a Tetravalent Dengue Vaccine Efficacy StudyCompletedNCT019835531 country
- Study of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Adacel® in Healthy SubjectsTerminatedNCT02992418Phase 31 country
- Study of a Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 11 Years in MalaysiaCompletedNCT01254422Phase 31 country
- Study of a Booster Injection of Pentaxim™ Vaccine Administered With Dengue Vaccine in Healthy ToddlersCompletedNCT01411241Phase 31 country
- Study of Yellow Fever Vaccine Administered With Tetravalent Dengue Vaccine in Healthy ToddlersCompletedNCT01436396Phase 32 countries
- Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Cervarix®CompletedNCT02979535Phase 31 country
- Immunogenicity and Safety of a Tetravalent Dengue Vaccine Administered Concomitantly or Sequentially With Gardasil®CompletedNCT02993757Phase 31 country
- Immunogenicity and Safety of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Children and Adolescents in Latin AmericaCompletedNCT00993447Phase 24 countries
- Immunogenicity and Safety of a Tetravalent Dengue Vaccine Booster Injection in Subjects Who Previously Completed a 3-dose ScheduleCompletedNCT02824198Phase 21 country
- Immune Response to Different Schedules of a Tetravalent Dengue Vaccine Given With or Without Yellow Fever VaccineCompletedNCT01488890Phase 21 country
- Study of a Booster Dose of a Tetravalent Dengue Vaccine in Subjects Who Previously Completed the 3-dose ScheduleCompletedNCT02623725Phase 25 countries
- Immunologic Mechanisms of Immune Interference and/or Cross-Neutralizing Immunity After CYD Tetravalent Dengue VaccineCompletedNCT01943825Phase 21 country
- Immunogenicity and Safety of Different Vaccination Schedules of Tetravalent Dengue Vaccine in Healthy Subjects 9 to 50 Years of AgeCompletedNCT02628444Phase 22 countries
- Study of CYD Dengue Vaccine in Healthy Children and Adolescents in South AmericaCompletedNCT01187433Phase 21 country
- Study of Sanofi Pasteur's CYD Dengue Vaccine in Healthy Subjects in SingaporeCompletedNCT00880893Phase 21 country
- Study of a Novel Tetravalent Dengue Vaccine in Healthy Children Aged 2 to 14 Years in AsiaCompletedNCT01373281Phase 35 countries
- Study of a Novel Tetravalent Dengue Vaccine in Healthy Children and Adolescents Aged 9 to 16 Years in Latin AmericaCompletedNCT01374516Phase 35 countries
- Pharmacokinetics and Pharmacodynamics of Ivermectin in Pediatric Dengue PatientsCompletedNCT03432442Phase 21 country
- Prospective Study for the Evaluation of Dengue Prognostic Biomarkers in SingaporeCompletedNCT040488371 country
- Study of a Tetravalent Dengue Vaccine in Healthy Adults in AustraliaCompletedNCT01134263Phase 31 country
- Immunogenicity and Safety of Three Formulations of Dengue Vaccines in Healthy Adults Aged 18 to 45 Years in the USCompletedNCT00617344Phase 21 country
- A Two-dose Primary Vaccination Study of a Tetravalent Dengue Virus Purified Inactivated Vaccine vs. Placebo in Healthy AdultsCompletedNCT01666652Phase 11 country
- Study of ChimeriVax™ Dengue Tetravalent Vaccine in Adult SubjectsCompletedNCT00730288Phase 21 country
- Prospective Dengue Seroprevalence Study in 5 to 10 Year-old ChildrenCompletedNCT014776711 country
- A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and ChildrenCompletedNCT00468858Phase 21 country
- A Two-dose Primary Vaccination Study of a Tetravalent Dengue Virus Purified Inactivated Vaccine vs. Placebo in Healthy Adults (in Puerto Rico)CompletedNCT01702857Phase 11 country
- Ketotifen as a Treatment for Vascular Leakage During Dengue FeverStatus unknownNCT02673840Phase 41 country
- Evaluating the Safety and Immune Response to Two Admixtures of a Tetravalent Dengue Virus VaccineCompletedNCT01436422Phase 11 country
- Safety and Immunogenicity of Formulations of Dengue Vaccines in Healthy Flavivirus-Naïve AdultsCompletedNCT00740155Phase 21 country