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Severe combined immunodeficiency due to adenosine deaminase deficiency clinical trials

The registry lists 29 studies for Severe combined immunodeficiency due to adenosine deaminase deficiency across 6 countries. 4 are recruiting or about to start. 23 of them are mainly about Severe combined immunodeficiency due to adenosine deaminase deficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.

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Status

Completed
15
Status unknown
4
Enrolling by invitation
3
Active, not recruiting
3
Withdrawn
3
Not yet recruiting
1

Phase

Phase 1
9
Phase 2
8
Phase 3
2
Phase 4
1

Where

United States
16
Italy
4
United Kingdom
4
Turkey
3
Canada
2
China
1

Who runs them

University of California, Los Angeles (5) · National Human Genome Research Institute (NHGRI) (4) · Fondazione Telethon (4) · TRPHARM (3) · Great Ormond Street Hospital for Children NHS Foundation Trust (3) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Istituto Giannina Gaslini (1) · Fred Hutchinson Cancer Center (1)

What is being tested here

Drugs under test in Severe combined immunodeficiency due to adenosine deaminase deficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Busulfan004
Cyclosporine001
Mycophenolic Acid001

Coming up

0phase 3 studies under way
2studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2

Who these studies take

No Severe combined immunodeficiency due to adenosine deaminase deficiency study is recruiting now.

Across all 29 studies, recruiting or not: 52% stop at 75 or younger and 52% at 65; 90% take children; 0% are for women only and 0% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 16, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 29 of 29. search them.