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Primary Immunodeficiency Diseases clinical trials

The registry lists 211 studies for Primary Immunodeficiency Diseases across more than 10 countries. 51 are recruiting or about to start. 150 of them are mainly about Primary Immunodeficiency Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 6 narrower conditions too, such as Angioedemas, Hereditary: 529 studies, 97 open.

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What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

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Status

Completed
111
Recruiting
35
Status unknown
25
Not yet recruiting
14
Active, not recruiting
11
Terminated
8

Phase

Phase 3
56
Phase 2
37
Phase 1
22
Phase 4
17
Early Phase 1
1

Where

United States
108
France
23
Canada
18
United Kingdom
11
Germany
10
Italy
9

Who runs them

National Institute of Allergy and Infectious Diseases (NIAID) (16) · Baxalta now part of Shire (14) · CSL Behring (11) · Octapharma (10) · Takeda (9) · Grifols Therapeutics LLC (8) · Bio Products Laboratory (5) · Federal Research Institute of Pediatric Hematology, Oncology and Immunology (4)

What is being tested here

Drugs under test in Primary Immunodeficiency Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Immunoglobulin G22329
Immunoglobulins, Intravenous22127
Melphalan203
Fludarabine102
Alemtuzumab102
Allogeneic CD34+-enriched and CD45RA-depleted PBSCs101
Nicotinamide-beta-riboside101
Hydroxyurea101
Thiotepa101
Albuterol101

Drug classes tested here Alkylating agents 2 open · Antimetabolites 1 open

Coming up

8phase 3 studies under way
16studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 35 Primary Immunodeficiency Diseases studies recruiting now, 12 (34%) set no upper age limit and 10 (29%) stop at 75 or younger. 28 (80%) take children under 18. 1 (3%) are for women only and 1 (3%) for men only; 11 (31%) take healthy volunteers.

Recruiting studies that take each age, of 35
AgeWomenMen
1027 (77%)27 (77%)
1834 (97%)34 (97%)
3031 (89%)31 (89%)
4031 (89%)31 (89%)
5031 (89%)31 (89%)
6527 (77%)27 (77%)
7526 (74%)26 (74%)
8520 (57%)19 (54%)

Across all 211 studies, recruiting or not: 49% stop at 75 or younger and 31% at 65; 82% take children; 1% are for women only and 2% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Primary Immunodeficiency Diseases studies take

Of 25 phase 3 interventional studies under Primary Immunodeficiency Diseases, half reached primary completion within 35 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 335 mo19–41 · 25 studies——
Observational72 mo30–… · 50 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 211. Browse all 211 → or search them.