Respiratory Distress Syndrome: all 1,619 studies

Page 4 of 17. Open to participants first (319), then studies with results posted, then the rest; newest registration first within each.

• Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q SystemEnrolling by invitationNCT04369599Not applicable
• Mesenchymal Stem Cells for The Treatment of Acute Respiratory Distress Syndrome (ARDS)Not yet recruitingNCT04347967Phase 1
• Forced Oscillometry in Infants With Bronchopulmonary DysplasiaRecruitingNCT04270045
• Early Use of Airway Pressure Release Ventilation (APRV) in ARDSRecruitingNCT04221737Not applicable
• Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial)RecruitingNCT04208126Not applicable
• Medium vs Low Oxygen Threshold for the Surfactant AdministrationNot yet recruitingNCT04199364Phase 4
• Optimal PEEP Titration Combining Transpulmonary Pressure Measurement and Electric Impedance TomographyRecruitingNCT04174014Not applicable
• China Extracorporeal Life Support RegistryRecruitingNCT04158479
• ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory FailureRecruitingNCT04031794
• The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean SectionNot yet recruitingNCT03899597Not applicable
• Alveolar Macrophage Programming Following Endotoxin ExposureRecruitingNCT03859050Not applicable
• Recovery From ICUAW Following Severe Respiratory and Cardiac FailureRecruitingNCT03753412
• High-Frequency Oscillation Ventilation Versus Conventional Mechanical Ventilation in Very Preterm Infants With Perinatal Acute Respiratory Distress Syndrome: Multicenters Randomized Controlled, Superiority TrialRecruitingNCT03736707Not applicable
• Premedication for Less Invasive Surfactant AdministrationRecruitingNCT03735563Phase 4
• The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICURecruitingNCT03642002Not applicable
• A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDSRecruitingNCT03549910Not applicable
• Use of Gentle Synchronized Negative Pressure in Helping Babies BreatheRecruitingNCT03510169Not applicable
• Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe TraumaRecruitingNCT03368092Phase 3
• European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and BiobankRecruitingNCT02852928
• Prehospital Telemedicine Feasibility/Acceptability PilotCompletedNCT05967624Not applicableResults posted
• Add-on Reparixin in Adult Patients With ARDSCompletedNCT05496868Phase 2Results posted
• Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm InfantsTerminatedNCT05030012Not applicableResults posted
• Tregs for the Treatment of Acute Respiratory Distress Syndrome (ARDS) Associated With COVID-19 (regARDS)TerminatedNCT05027815Phase 1Results posted
• Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 PatientsCompletedNCT04973488Not applicableResults posted
• Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory DistressCompletedNCT04935697Not applicableResults posted
• Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)TerminatedNCT04870125Phase 1Results posted
• Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19TerminatedNCT04778059Phase 2Results posted
• Restore Resilience in Critically Ill ChildrenCompletedNCT04695392Not applicableResults posted
• Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) StudyCompletedNCT04663802Not applicableResults posted
• A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19CompletedNCT04640194Phase 2/3Results posted
• Double-blind, Randomized, Controlled Clinical Trial to Assess Efficacy of MSC in Patients With COVID-19 ARDSCompletedNCT04615429Phase 2Results posted
• Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS)CompletedNCT04581811Not applicableResults posted
• Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Acute Respiratory Distress Syndrome (ARDS) Associated With at Least Severe COVID-19TerminatedNCT04565249Phase 2Results posted
• The Budesonide in Babies (BiB) TrialActive, not recruitingNCT04545866Phase 3Results posted
• A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19)TerminatedNCT04537806Phase 3Results posted
• Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS)CompletedNCT04530604Phase 1Results posted
• Study of Descartes-30 in Acute Respiratory Distress SyndromeTerminatedNCT04524962Phase 1Results posted
• Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019TerminatedNCT04511650Phase 2Results posted
• Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)TerminatedNCT04502433Phase 2Results posted
• Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)CompletedNCT04478071Phase 2Results posted
• Efficacy and Safety of Itolizumab in COVID-19 ComplicationsCompletedNCT04475588Phase 2Results posted
• Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)CompletedNCT04466098Phase 2Results posted
• Efficacy, Safety, Tolerability, and Biomarkers of Ibudilast (MN-166) in Patients Hospitalized With COVID-19 at Risk for ARDSCompletedNCT04429555Phase 2Results posted
• LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)CompletedNCT04402957Phase 2Results posted
• A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19CompletedNCT04402060Phase 1/2Results posted
• EASiVENT Study Comparing INTELLiVENT-ASV vs Non Automated Ventilation in Adult ICU PatientsTerminatedNCT04400643Results posted
• hCT-MSCs for COVID19 ARDSTerminatedNCT04399889Phase 1/2Results posted
• The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19)CompletedNCT04389671Phase 2Results posted
• COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111CompletedNCT04388826Phase 2Results posted
• Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory SymptomsTerminatedNCT04382391Not applicableResults posted
• Tocilizumab for Patients With Cancer and COVID-19 DiseaseTerminatedNCT04370834Phase 2Results posted
• Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe PneumoniaTerminatedNCT04369469Phase 3Results posted
• Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19TerminatedNCT04365985Phase 2Results posted
• Prazosin to Prevent COVID-19 (PREVENT-COVID Trial)TerminatedNCT04365257Phase 2Results posted
• Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 InfectionCompletedNCT04357730Phase 2Results posted
• Use of UC-MSCs for COVID-19 PatientsCompletedNCT04355728Phase 1/2Results posted
• A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)CompletedNCT04351243Phase 2Results posted
• Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurETerminatedNCT04347941Not applicableResults posted
• Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease)CompletedNCT04345601Phase 1/2Results posted
• Pre-exposure Prophylaxis for SARS-Coronavirus-2CompletedNCT04328467Phase 3Results posted
• Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDSCompletedNCT04325906Not applicableResults posted
• Methylprednisolone for Patients With COVID-19 Severe Acute Respiratory SyndromeCompletedNCT04323592Results posted
• Losartan for Patients With COVID-19 Requiring HospitalizationCompletedNCT04312009Phase 2Results posted
• Intravenous Aviptadil for Critical COVID-19 With Respiratory FailureCompletedNCT04311697Phase 2/3Results posted
• Losartan for Patients With COVID-19 Not Requiring HospitalizationCompletedNCT04311177Phase 2Results posted
• Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2CompletedNCT04308668Phase 3Results posted
• Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19TerminatedNCT04305457Phase 2Results posted
• Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and FunctionCompletedNCT04295564Not applicableResults posted
• Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance RecoveryCompletedNCT04291508Phase 2Results posted
• A Safety and Efficacy Study of Lucinactant for Inhalation in Preterm Neonates 26 to 32 Weeks Gestational AgeTerminatedNCT04264156Phase 2Results posted
• ABCA3 Gene and RDS in Late Preterm and Term InfantsCompletedNCT04137783Results posted
• Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress SyndromeCompletedNCT04113434Results posted
• Inhaled Steroids for the Treatment of Early Pediatric Acute Respiratory Distress SyndromeTerminatedNCT04064684Phase 2Results posted
• A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFactCompletedNCT03969992Phase 2Results posted
• Mesenchymal Stromal Cells For Acute Respiratory Distress SyndromeCompletedNCT03818854Phase 2Results posted
• Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)CompletedNCT03799874Phase 2Results posted
• Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress SyndromeCompletedNCT03793842Not applicableResults posted
• Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm InfantsTerminatedNCT03558737Not applicableResults posted
• A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks GestationCompletedNCT03292562Not applicableResults posted
• A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Following ExtubationCompletedNCT03181958Not applicableResults posted
• Comparison of CPAP Machines With Reusable vs Disposable CircuitsTerminatedNCT03121612Not applicableResults posted
• NHFOV vs. NCPAP as a Primary Treatment to Neonatal Respiratory Distress Syndrome(NRDS)CompletedNCT03099694Not applicableResults posted
• Vitamin D to Improve Outcomes by Leveraging Early TreatmentCompletedNCT03096314Phase 3Results posted
• Comparison of Aerosol Delivery of Infasurf to Usual Care in Spontaneously Breathing RDS PatientsCompletedNCT03058666Phase 3Results posted
• A Study Promoting Critical Illness Recovery in the ElderlyCompletedNCT02963558Not applicableResults posted
• Does a Rescue Course of Betamethasone in Pregnant Women With PPROM Decrease Neonatal Morbidity?TerminatedNCT02939742Phase 2/3Results posted
• Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress SyndromeCompletedNCT02834624Not applicableResults posted
• Effective Approaches & Strategies to Ease Off Nasal CPAP In Preterm InfantsCompletedNCT02819050Not applicableResults posted
• A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional AdministrationTerminatedNCT02772081Phase 3Results posted
• External Nasal Dilator and Oxygen Therapy in Respiratory FailureCompletedNCT02662387Not applicableResults posted
• Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in NeonatesCompletedNCT02661256Not applicableResults posted
• The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational AgeCompletedNCT02636868Phase 2Results posted
• Efficacy and Safety of FP-1201-lyo (Interferon Beta-1a) in Patients Having Acute Respiratory Distress Syndrome (ARDS)TerminatedNCT02622724Phase 3Results posted
• Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress SyndromeCompletedNCT02582957Not applicableResults posted
• Trial To Assess The Safety And Tolerability Of Lucinactant For Inhalation In Preterm Neonates 26 to 28 Weeks PMATerminatedNCT02528318Phase 2Results posted
• Reevaluation Of Systemic Early Neuromuscular BlockadeCompletedNCT02509078Phase 3Results posted
• Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDSCompletedNCT02463773Not applicableResults posted
• A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)CompletedNCT02452476Phase 2Results posted
• Comparative Effectiveness Study of Bubble CPAP Devices in the NICUCompletedNCT02392806Not applicableResults posted
• Treprostinil Sodium Inhalation for Patients At High Risk for ARDSTerminatedNCT02370095Phase 2Results posted

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