Respiratory Distress Syndrome, Newborn: all 1,179 studies

Page 2 of 12. Open to participants first (160), then studies with results posted, then the rest; newest registration first within each.

• InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDSRecruitingNCT05960929Phase 3
• Spinal Cord Stimulation to Shorten Ventilator Dependence in ARDS PatientsRecruitingNCT05928052Not applicable
• Safety of Low PEEP Maneuvers During ARDS ManagementRecruitingNCT05922969
• Efficacy and Safety of Anakinra in Acute Respiratory Distress SyndromeRecruitingNCT05914454Phase 2
• Biomarkers to Predict Acute Respiratory Distress Syndrome(ARDS) in Patients With SepsisRecruitingNCT05914428
• Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm InfantsRecruitingNCT05908227Not applicable
• Fluid Responsiveness Prediction During Prone PositionRecruitingNCT05898269Not applicable
• Two-year Efficacy of Three Exercise Rehabilitation Strategies on Dyspnea in Patients Who Presented With Secondary Respiratory Distress Syndrome Secondary to Severe COVID-19 PneumoniaRecruitingNCT05890560
• Validity of Lung Ultrasound in Diagnosis of Acute Respiratory Distress SyndromeRecruitingNCT05886556
• The Effect of Erythropoietin on Alveolar Fluid Clearance in Patients With Acute Respiratory Distress SyndromeRecruitingNCT05857891Not applicable
• Inhaled Sevoflurane for ARDS PreventionRecruitingNCT05849779Phase 3
• Effect of High Flow Nasal Cannula Versus Nasal Continuous Positive Airway PressureNot yet recruitingNCT05849116
• Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot AnalysisRecruitingNCT05847634
• The ICU LIBERATION StudyRecruitingNCT05844579
• Antenatal Dexamethasone for Late Preterm DeliveriesRecruitingNCT05841121Phase 1
• Early PP Monitored by EIT in Patients With ARDSRecruitingNCT05822869Not applicable
• REspiratory MEchanics for Delivering Individualised Exogenous SurfactantNot yet recruitingNCT05791331Not applicable
• Using TEE to Evaluate the Effect of Levosimendan on Patients With ARDS Associated With RVD During MVNot yet recruitingNCT05768230Phase 2/3
• Sedative Effect and Safety of Remimazolam Besylate in ARDS PatientsRecruitingNCT05758597Phase 4
• Transbronchial Lung Cryobiopsy in Undiagnosed Acute Respiratory FailureRecruitingNCT05754866Not applicable
• Closed-loop Synchronization Versus Conventional SynchronizationRecruitingNCT05731024Not applicable
• Infant Respiratory Interface and Accessories Evaluation StudyNot yet recruitingNCT05719298Not applicable
• Changes in Lung Aeration and Inspiratory Effort With and Without Awake ProneRecruitingNCT05719103Not applicable
• Comparison of INRECSURE and LISA in Preterm Neonates With RDSRecruitingNCT05711966Not applicable
• Prognostic Value of PtcO2 in Patients With COVID-19RecruitingNCT05682612
• Optimization and Clinical Study of Early Prediction Model for Neonatal Acute Respiratory Distress SyndromeRecruitingNCT05647850
• Inflammation During ECMO Therapy and ECMO WeaningRecruitingNCT05640635Not applicable
• NeO2Matic-Pilot TrialNot yet recruitingNCT05629910Not applicable
• The NONA-LISA TrialRecruitingNCT05609877Not applicable
• European Registry for Hemadsorption in Sepsis With the Seraph FilterRecruitingNCT05608096
• Trial of Venovenous ECMO to De-Sedate, Extubate and Mobilise in Hypoxic Respiratory FailureRecruitingNCT05562505Not applicable
• Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress SyndromeRecruitingNCT05535543
• University Hospital of Ioannina COVID-19 (Coronavirus Disease 2019) RegistryRecruitingNCT05534074
• 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDSRecruitingNCT05514483Phase 4
• Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDSRecruitingNCT05474196
• Personalized Tidal Volume in ARDS (VT4HEMOD)RecruitingNCT05406570Not applicable
• Recruitment Assessment in Patients With Acute Respiratory Distress Syndrome and Covid-19RecruitingNCT05248243
• Clinical Pharmacology of Dexamethasone in Pregnant Women With Preterm LaborRecruitingNCT05207852
• Impact of COVID-19 SARS-CoV-2 Variability in ICU Hospitalized Patients With Severe DiseaseRecruitingNCT05162508
• Comparison of Prone Position and Standard Electrocardiogram in COVID-19 PatientsRecruitingNCT05047835
• Infantile NO Replenishment as a New Therapeutic PossibilityRecruitingNCT04914806
• Ultra-Protective Lung Ventilation With Extracorporeal CO2 Removal for Moderate ARDSRecruitingNCT04903262Not applicable
• Intratracheal Budesonide With Surfactant to Prevent Bronchopulmmonary Dysplasia.Not yet recruitingNCT04862377Phase 3
• Pilot Clinical Study of NOA-001 for ARDS (Acute Respiratory Distress Syndrome)RecruitingNCT04804943Not applicable
• Reduction of Blood Recirculation in Veno-Venous ECMORecruitingNCT04754854
• Expanded Access to Zofin for Patients With COVID-19AvailableNCT04657406
• Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS)RecruitingNCT04503057
• Outcome of Patients Treated With ECLSRecruitingNCT04405817
• Lessening Organ Dysfunction With VITamin C in Septic ARDSRecruitingNCT04404387Phase 3
• Mesenchymal Stem Cells for The Treatment of Acute Respiratory Distress Syndrome (ARDS)Not yet recruitingNCT04347967Phase 1
• Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial)RecruitingNCT04208126Not applicable
• Medium vs Low Oxygen Threshold for the Surfactant AdministrationNot yet recruitingNCT04199364Phase 4
• China Extracorporeal Life Support RegistryRecruitingNCT04158479
• ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory FailureRecruitingNCT04031794
• The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean SectionNot yet recruitingNCT03899597Not applicable
• Premedication for Less Invasive Surfactant AdministrationRecruitingNCT03735563Phase 4
• The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICURecruitingNCT03642002Not applicable
• A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDSRecruitingNCT03549910Not applicable
• Use of Gentle Synchronized Negative Pressure in Helping Babies BreatheRecruitingNCT03510169Not applicable
• European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and BiobankRecruitingNCT02852928
• Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm InfantsTerminatedNCT05030012Not applicableResults posted
• Tregs for the Treatment of Acute Respiratory Distress Syndrome (ARDS) Associated With COVID-19 (regARDS)TerminatedNCT05027815Phase 1Results posted
• Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 PatientsCompletedNCT04973488Not applicableResults posted
• Safety and Efficacy of USB002 for Respiratory Distress Due to COVID-19TerminatedNCT04778059Phase 2Results posted
• Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) StudyCompletedNCT04663802Not applicableResults posted
• A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19CompletedNCT04640194Phase 2/3Results posted
• Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS)CompletedNCT04581811Not applicableResults posted
• Evaluation of the Safety, Tolerability, and Pharmacokinetics of PLN-74809 in Participants With Acute Respiratory Distress Syndrome (ARDS) Associated With at Least Severe COVID-19TerminatedNCT04565249Phase 2Results posted
• A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19)TerminatedNCT04537806Phase 3Results posted
• Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS)CompletedNCT04530604Phase 1Results posted
• Study of Descartes-30 in Acute Respiratory Distress SyndromeTerminatedNCT04524962Phase 1Results posted
• Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019TerminatedNCT04511650Phase 2Results posted
• Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)TerminatedNCT04502433Phase 2Results posted
• Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19)CompletedNCT04478071Phase 2Results posted
• Efficacy and Safety of Itolizumab in COVID-19 ComplicationsCompletedNCT04475588Phase 2Results posted
• Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)CompletedNCT04466098Phase 2Results posted
• A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19CompletedNCT04402060Phase 1/2Results posted
• EASiVENT Study Comparing INTELLiVENT-ASV vs Non Automated Ventilation in Adult ICU PatientsTerminatedNCT04400643Results posted
• The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19)CompletedNCT04389671Phase 2Results posted
• COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111CompletedNCT04388826Phase 2Results posted
• Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory SymptomsTerminatedNCT04382391Not applicableResults posted
• Tocilizumab for Patients With Cancer and COVID-19 DiseaseTerminatedNCT04370834Phase 2Results posted
• Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe PneumoniaTerminatedNCT04369469Phase 3Results posted
• Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19TerminatedNCT04365985Phase 2Results posted
• Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 InfectionCompletedNCT04357730Phase 2Results posted
• Use of UC-MSCs for COVID-19 PatientsCompletedNCT04355728Phase 1/2Results posted
• A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE)CompletedNCT04351243Phase 2Results posted
• Pre-exposure Prophylaxis for SARS-Coronavirus-2CompletedNCT04328467Phase 3Results posted
• Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDSCompletedNCT04325906Not applicableResults posted
• Losartan for Patients With COVID-19 Requiring HospitalizationCompletedNCT04312009Phase 2Results posted
• Intravenous Aviptadil for Critical COVID-19 With Respiratory FailureCompletedNCT04311697Phase 2/3Results posted
• Losartan for Patients With COVID-19 Not Requiring HospitalizationCompletedNCT04311177Phase 2Results posted
• Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2CompletedNCT04308668Phase 3Results posted
• Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance RecoveryCompletedNCT04291508Phase 2Results posted
• A Safety and Efficacy Study of Lucinactant for Inhalation in Preterm Neonates 26 to 32 Weeks Gestational AgeTerminatedNCT04264156Phase 2Results posted
• ABCA3 Gene and RDS in Late Preterm and Term InfantsCompletedNCT04137783Results posted
• Inhaled Steroids for the Treatment of Early Pediatric Acute Respiratory Distress SyndromeTerminatedNCT04064684Phase 2Results posted
• Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress SyndromeCompletedNCT03793842Not applicableResults posted
• Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm InfantsTerminatedNCT03558737Not applicableResults posted
• Pulmonary Function Using Non-invasive Forced OscillometryActive, not recruitingNCT03346343Not applicableResults posted

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