Rectal Neoplasms: all 1,804 studies

Page 9 of 19. Open to participants first (520), then studies with results posted, then the rest; newest registration first within each.

• Indocyanine Green-guided Lymphadenectomy in Laparoscopic Total Mesorectal Excision for Low Rectal Cancer After Neoadjuvant ChemoradiotherapyStatus unknownNCT05873621Not applicable
• Induction Chemotherapy Followed by Short Course Radiotherapy in Rectal CancerActive, not recruitingNCT05868317Phase 2
• SCRT in TNT With or Without ChlorophyllinActive, not recruitingNCT05856305Phase 2
• Re-irradiation for Pelvic Recurrences in Rectal Cancer PatientsCompletedNCT05816980Phase 2
• Clinical Study to Compare the Pharmacokinetics and Safety of Ramucirumab Injection With Cyramza ® in Healthy Male VolunteersCompletedNCT05800418Phase 1
• Neoadjuvant Cadonilimab Plus Chemotherapy Following Short-Course Radiotherapy in Locally Advanced Rectal CancerCompletedNCT05792735Phase 2
• Neoadjuvant Therapy for Locally Advanced Rectal Cancer With Fruquintinib, Toripalimab and SRTStatus unknownNCT05763927Phase 2
• Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning IleostomyStatus unknownNCT05759741Early Phase 1
• Trial Comparing Loop Ileostomy Versus Loop Transverse ColostomyCompletedNCT05745909Not applicable
• A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid TumorsActive, not recruitingNCT05726864Phase 1/2
• Using Artificial Intelligence to Predict Rectal Cancer OutcomesCompletedNCT05723965
• A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal CancerActive, not recruitingNCT05723562Phase 2
• Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal CancersActive, not recruitingNCT05722288Phase 2
• Adaptive Symptom Self-Management Immunotherapy StudyActive, not recruitingNCT05715255Not applicable
• Dosimetric Limitation of Pelvic Bone and Peritoneal Space in Rectal Cancer Patients During ChemoradiotherapyStatus unknownNCT05688033Not applicable
• Radiation-induced Diarrhoea During Curative EBRT of Prostate and Rectal CancerCompletedNCT05684432
• Transanal Versus Laparoscopic Total Mesorectal Excision: a CohortCompletedNCT05682794
• Paula Method of Exercises in Patients With LARS Syndrome:Randomized Controlled TrialCompletedNCT05682157Not applicable
• GEMCAD-REVEAL STUDY - Circulating Tumor DNA as a Predictor of Relapse in Patients With Locally Advanced Rectal Cancer.Active, not recruitingNCT05674422
• Blood Flow Path Reconstruction in Rectal CancerCompletedNCT05674097
• Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal CancerActive, not recruitingNCT05673772Phase 2
• The Prognostic Impact Of The Neutrophil To Lymphocyte Ratio In Patients With Locally Advanced Rectal CancerStatus unknownNCT05673343
• Prognostic Significance of Lymph Node Ratio in Rectal Cancer on Overall SurvivalCompletedNCT05667259
• The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal CancerCompletedNCT05667181Not applicable
• Use of VIrtual REAlity to Reduce Postoperative Anxiety and Pain After Surgery for Colorectal CancerStatus unknownNCT05653934Not applicable
• FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal CancerActive, not recruitingNCT05627635Phase 1/2
• Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal CancerCompletedNCT05622357Phase 2
• Tumor Budding in Patients With Colorectal Cancer Under Different MMR StatusCompletedNCT05610592
• Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation and Continuing ResponseActive, not recruitingNCT05610163Phase 2/3
• MRI Features in Neoadjuvant Treatment Decisions for Patients With Rectal CancerCompletedNCT05609149
• Outcomes of Neoadjuvant Therapy for Rectal Cancer in a Tertiary Asian InstituteCompletedNCT05607186
• Oncological Impact of Lateral Nodes in Rectal CancerCompletedNCT05592873
• Endorectal Brachytherapy for Rectal CancerSuspendedNCT05591534Phase 2
• Determining the Optimal Examined Lymph Node for Accurate Staging and Long-term Survival in Rectal CancerCompletedNCT05572151
• F-Tryptophan PET/CT in Human CancersCompletedNCT05556473Phase 1
• A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersActive, not recruitingNCT05544929Phase 1
• Snapshot Rectumcarcinoom 2016CompletedNCT05539417
• Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid TumorsCompletedNCT05538195Phase 1/2
• Assessment of Complete Response MRI Criterion After Neoadjuvant Therapy in Locally Advanced Rectal CancerCompletedNCT05534841
• Watchful Waiting for Complete Responders to Therapy in Rectal CancerTerminatedNCT05526079Not applicable
• Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal CancerActive, not recruitingNCT05524012
• Application of ICG in Lymph Node Dissection During Radical Resection of Rectal Cancer With Preserved Autonomic Nerves Around LCA and IMACompletedNCT05517681Not applicable
• Prebiotics in Rectal CancerStatus unknownNCT05516641Not applicable
• Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal TumorsCompletedNCT05515796Phase 2
• TIME in Immunotherapy Combined With nCRT for Rectal CancerActive, not recruitingNCT05507112Phase 2
• Multiple Firings in Double-stapled Colorectal AnastomosisCompletedNCT05498506
• Surgery Alone Versus Neoadjuvant Treatment Followed by Surgery For MRI-defined T3 Mid-low Rectal CancerCompletedNCT05496270
• "Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".CompletedNCT05495308
• A Lymph Node Metastasis Predictor (LN-MASTER) in Rectal CancerCompletedNCT05493930
• Evaluating Novel Therapies in ctDNA Positive GI CancersActive, not recruitingNCT05482516Phase 3
• Incidence, Risk Factor, Treatment and Overall Survival of Locally Recurrent Rectal CancerCompletedNCT05475301
• Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid TumorsActive, not recruitingNCT05462717Phase 1
• Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal CancerCompletedNCT05461248Not applicable
• Immune Checkpoints in Predicting Response to Neoadjuvant Therapy in Rectal CancerCompletedNCT05457075
• The Longitudinal Study of Low Anterior Resection Syndrome in Patients with Newly Diagnosed Rectal Cancer.CompletedNCT05445245
• Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical TrialStatus unknownNCT05411783Not applicable
• Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in CancerSuspendedNCT05400122Phase 1
• The Role of TextRAd on Detection of Liver Metastasis in Rectal CancerCompletedNCT05398822
• Evaluating Factors Affecting Survival in Colon and Rectum CancerCompletedNCT05388513
• Establishment of MRI Model for pTRG in Rectal Cancer With Establishment ofActive, not recruitingNCT05374044
• A Combination Therapy Including Anti-PD-1 Immunotherapy in Rectal Cancer With Refractory Distal MetastasisStatus unknownNCT05359406Phase 2
• Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal CancerSuspendedNCT05358704Phase 2
• Circulating Tumor DNA to Monitor the Efficacy of Total Neoadjuvant Therapy for Rectal CancerWithdrawnNCT05356585
• Therascreen® KRAS RGQ PCR KitCompletedNCT05347745Not applicable
• Long Term Bowel Function Following Rectal Cancer SurgeryCompletedNCT05339763Not applicable
• Radioisotope and Fluorescence Guidance in Rectal CancerStatus unknownNCT05336643Not applicable
• Radiomics in Rectal CancerWithdrawnNCT05331040
• Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF MutationActive, not recruitingNCT05308446Phase 2
• Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal MalignancyActive, not recruitingNCT05305820Not applicable
• Efferent Loop Stimulation Previous to Ileostomy Closure. Ileostim Trial.Status unknownNCT05302557Not applicable
• Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer SurgeryCompletedNCT05293054
• Prehabilitation in Rectal Cancer: During Neoadjuvant Therapy vs PreoperativeStatus unknownNCT05286086Not applicable
• Timing Evaluation of Stoma Closure (TIMES). Early vs Late Closure of Stoma After Rectal Cancer Surgery.Status unknownNCT05284864Not applicable
• Total Neoadjuvant Therapy Versus Standard Neoadjuvant Chemoradiation for Locally Advanced Rectal CancerCompletedNCT05274945Phase 2
• Intraoperative Angiography Using ICG in Rectal Cancer Patients to Prevent Anastamotic Leak After Laparoscopic Anterior Resection of the RectumStatus unknownNCT05263336Not applicable
• An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal CancerActive, not recruitingNCT05245786Early Phase 1
• Transanal Irrigation for Low Anterior Resection Syndrome.Active, not recruitingNCT05245331Not applicable
• Planned Non-operative Management for Rectal CancerStatus unknownNCT05241574Phase 2
• A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal CancerActive, not recruitingNCT05217446Phase 2
• Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma (PRECAM)CompletedNCT05216653Phase 2
• Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal CancerCompletedNCT05215379Phase 2/3
• Bacteriological Differences Between Transanal and Laparoscopic Total Mesorectal Excision for Rectal Cancer.Status unknownNCT05201872
• Reversal of a Defunctioning Ileostomy 3 Weeks After the Index Operation, RCTStatus unknownNCT05192018Not applicable
• Tempus Priority Study: A Pan-tumor Observational StudyActive, not recruitingNCT05179824
• Comparison Between Tailored Surgery Versus Total Mesorectal Excision in ycT2-3N0M0TerminatedNCT05164315Not applicable
• Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic MalignancyStatus unknownNCT05154474
• A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal CancerCompletedNCT05130060Phase 1
• Development and Validation of The Post-RT LARS Prediction Model (PORTLARS)CompletedNCT05129215
• Change of Circulating Tumor Cells During Laparoscopic or Transanal Endoscopic Surgery for Rectal Cancer.Active, not recruitingNCT05109130
• Short-term Outcomes of Transanal Total Mesorectal Excision With Structured Training Curriculums in ChinaCompletedNCT05108753
• Adaptive Radiation for Locally Advanced Rectal AdenocarcinomaActive, not recruitingNCT05108428Early Phase 1
• Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal CancerCompletedNCT05086627Phase 2
• Brazilian Total Neoadjuvant Therapy TrialStatus unknownNCT05081687Phase 3
• Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal CancerStatus unknownNCT05079503Not applicable
• Dendrobium Huoshanense Suppository in Rectal CancerStatus unknownNCT05079438Phase 3
• Multicenter Validation of the PREDICT ScoreCompletedNCT05078515
• PelvEx 4: Advanced Pelvic Malignancy and the Role of the Multi-disciplinary Team MeetingStatus unknownNCT05076305
• Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly PatientsStatus unknownNCT05068180Phase 4
• Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)Active, not recruitingNCT05056077Not applicable
• Consolidation Versus Induction Chemotherapy in Total Neoadjuvant Therapy of Rectal Cancer With High Risk for RecurrenceActive, not recruitingNCT05054959Phase 2

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