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Periapical Diseases clinical trials

The registry lists 46 studies for Periapical Diseases across more than 10 countries. 10 are recruiting or about to start. 32 of them are mainly about Periapical Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its narrower condition Periapical Periodontitis too: 315 studies, 87 open.

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Status

Completed
28
Status unknown
6
Recruiting
5
Not yet recruiting
5
Active, not recruiting
2

Phase

Phase 2
4
Phase 1
1

Where

Turkey
10
Egypt
7
India
4
United States
3
Italy
2
Pakistan
2

Who runs them

Ain Shams University (5) · Postgraduate Institute of Dental Sciences Rohtak (4) · University of Bologna (3) · Istanbul Medipol University Hospital (2) · Cukurova University (2) · Cairo University (2) · Islamabad Medical and Dental College (2) · Ministry of Health, Kuwait (2)

What is being tested here

Drugs under test in Periapical Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Calcium Hydroxide101
Iodoform101
Nanocurcumin001
Curcumin001
Curcumin-based Gel001
Ciprofloxacin001
Aloe vera gel001
Methylene Blue001

Coming up

0phase 3 studies under way
4studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4

Who these studies take

Of the 5 Periapical Diseases studies recruiting now, 3 (60%) set no upper age limit and 1 (20%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (20%) take healthy volunteers.

Recruiting studies that take each age, of 5
AgeWomenMen
100 (0%)0 (0%)
185 (100%)5 (100%)
305 (100%)5 (100%)
405 (100%)5 (100%)
505 (100%)5 (100%)
654 (80%)4 (80%)
754 (80%)4 (80%)
853 (60%)3 (60%)

Across all 46 studies, recruiting or not: 63% stop at 75 or younger and 57% at 65; 30% take children; 2% are for women only and 2% for men only; 54% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Periapical Diseases studies take

Of 27 interventional studies with no phase under Periapical Diseases, half reached primary completion within 24 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase24 mo12–32 · 27 studies—24 mo12–32 · 27 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 46 of 46. search them.