Ornithine Carbamoyltransferase Deficiency Disease: all 59 studies

Page 1 of 1. Open to participants first (13), then studies with results posted, then the rest; newest registration first within each.

• Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCDRecruitingNCT07773246Phase 1/2
• Epiretinal Membrane in Patients With DR.Not yet recruitingNCT07241845
• Long-term Follow-up (LTFU) Study of Participants in Any iECURE Protocol Using an Investigational Product (IP)RecruitingNCT06805695
• Role of OCT & OCT Angiography in Patients With Posterior at the Uveitis Clinic of Assiut University Hospital.Not yet recruitingNCT06743906
• Outside the Cage (OTC) Robotic EsophagectomyNot yet recruitingNCT06735638Phase 1
• A Study to Evaluate the Pharmacodynamics and Safety of ARCT-810 in Participants With OTCDRecruitingNCT06488313Phase 2
• Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in KazakhstanRecruitingNCT05910151
• Ovarian Tissue Cryopreservation in Pre-Pubertal (OTC-Pre Pubertal)RecruitingNCT05299710
• Halting Ornithine Transcarbamylase Deficiency With Recombinant AAV in ChildrEnRecruitingNCT05092685Phase 1/2
• Hepatic Histopathology in Urea Cycle DisordersRecruitingNCT04908319
• Systemic Biomarkers of Brain Injury From HyperammonemiaRecruitingNCT04602325
• Abbott Vascular Medical Device RegistryRecruitingNCT04573660
• Optical Coherence Tomography And NEphropathy: The OCTANE StudyRecruitingNCT02132741
• Low Cost OCT for Point of CareCompletedNCT03323307Not applicableResults posted
• Manipulating the Gut Microbiome StudyTerminatedNCT03181828Phase 1/2Results posted
• Safety and Dose-Finding Study of DTX301 (scAAV8OTC) in Adults With Late-Onset Ornithine Transcarbamylase (OTC) DeficiencyCompletedNCT02991144Phase 1/2Results posted
• Efficacy of Acupuncture in Macular DiseasesCompletedNCT02255981Not applicableResults posted
• Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs)TerminatedNCT01948427Results posted
• Observational Study of OCT in a Patients Undergoing FFRCompletedNCT01663896Results posted
• Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute HyperammonemiaCompletedNCT01599286Phase 2Results posted
• Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRICompletedNCT01569568Results posted
• Neurologic Injuries in Adults With Urea Cycle DisordersCompletedNCT00472732Results posted
• Looking for VUS to Confirm Dominant Wolfram-like Syndrome Instead of Recessive Wolfram SyndromeActive, not recruitingNCT07485413
• Radiomic Analysis in OCT Imaging of Acquired Vitelliform Lesions.CompletedNCT07074041
• Chuvashia Inappropriate Prescribing StudyCompletedNCT06845397
• Visual (Path)Ways in Multiple Sclerosis - Part IICompletedNCT06776224Not applicable
• Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram in GlaucomaCompletedNCT06431113Phase 3
• An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC DeficiencyActive, not recruitingNCT06255782Phase 3
• Study of CMP-CPS-001 in Healthy Volunteers and Participants With Abnormal Heterozygous OTC GenotypeActive, not recruitingNCT06247670Phase 1
• Baby Detect : Genomic Newborn ScreeningCompletedNCT05687474
• Study for Adolescents and Adults With Ornithine Transcarbamylase Deficiency to Evaluate Safety and Tolerability of ARCT-810TerminatedNCT05526066Phase 2
• AI Quantitative Coronary Angiography Versus Optical Coherent Tomography Guidance for Coronary Stent ImplantationCompletedNCT05388357Not applicable
• Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) DeficiencyActive, not recruitingNCT05345171Phase 3
• CAlcified Lesion Intervention Planning Steered by OCT.Status unknownNCT05301218Not applicable
• Adeno-Associated Virus (AAV) Antibody Study in Subjects OTC Deficiency, GSDIa, and Wilson DiseaseTerminatedNCT04909346
• Study to Characterize Rate of Ureagenesis in Patients With Ornithine Transcarbamylase (OTC) DeficiencyTerminatedNCT04717453
• Liver Disease in Urea Cycle DisordersActive, not recruitingNCT04612764
• Impact of OCT Imaging on Decision Making During PCI in ACS PatientsCompletedNCT04444037
• Phase 1b Study to Assess Safety, Tolerability, and Pharmacokinetics of ARCT-810 in Stable Adult Subjects With Ornithine Transcarbamylase DeficiencyCompletedNCT04442347Phase 1
• Safety, Tolerability and Pharmacokinetics of ARCT-810 in Healthy Adult SubjectsCompletedNCT04416126Phase 1
• A Study to Assess Plasma Ammonia Time-Normalized Area Under the Curve and Rate of Ureagenesis in Healthy Adult SubjectsCompletedNCT04269122
• Patient and Observer Reported Outcome Measurements in Inborn Errors of MetabolismCompletedNCT04248062
• UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle DisorderTerminatedNCT03933410Phase 2
• Safety, Tolerability and PK/PD Evaluation of Intravenous Administration of MRT5201 in Patients With OTC DeficiencyWithdrawnNCT03767270Phase 1/2
• Early Check: Expanded Screening in NewbornsActive, not recruitingNCT03655223
• Long Term Follow Up to Evaluate DTX301 in Adults With Late-Onset OTC DeficiencyActive, not recruitingNCT03636438
• Serial OCT Evaluation of Tissue Coverage in Patients Submitted to Inspiron Drug Eluting Stent ImplantationCompletedNCT03269461Not applicable
• FFR or OCT Guidance to RevasculariZe Intermediate Coronary Stenosis Using AngioplastyStatus unknownNCT01824030Phase 3
• Study of FTY720 in Patients With UveitisWithdrawnNCT01791192Phase 2
• A Study Comparing Two Stent on the Degree of Early Stent Healing and Late Lumen Loss.The OCT-ORION StudyCompletedNCT01742507Phase 4
• Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young InfantsCompletedNCT01624311Phase 2
• A Study Investigating the Pharmacokinetic Profiles of Four Extended Release Paracetamol FormulationsCompletedNCT01568749Phase 1
• The NIH UNI Study: Urea Cycle Disorders, Nutrition and ImmunityTerminatedNCT01421888
• Hepatocyte Transplantation for Liver Based Metabolic DisordersTerminatedNCT01345578Phase 1
• Vessel Wall Response of the Bio-Active-stent and Everolimus-Eluting Stent Assessed By Optical Coherence TomographyCompletedNCT01080859
• Human Heterologous Liver Cells for Infusion in Children With Urea Cycle DisordersCompletedNCT00718627Phase 2
• Age-related Macular Degeneration: Detection of Onset of New Choroidal Neovascularization (AMD DOC Study)CompletedNCT00417846
• Phase I Study of Adenoviral Vector Mediated Gene Transfer for Ornithine Transcarbamylase in Adults With Partial Ornithine Transcarbamylase DeficiencyTerminatedNCT00004498Phase 1
• Phase I Pilot Study of Liver-Directed Gene Therapy for Partial Ornithine Transcarbamylase DeficiencyTerminatedNCT00004386Phase 1

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