Opportunistic Infections clinical trials
The registry lists 41 studies for Opportunistic Infections across more than 10 countries. 12 are recruiting or about to start. 10 of them are mainly about Opportunistic Infections (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 2 narrower conditions too, such as AIDS-Related Opportunistic Infections: 250 studies, 16 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (7) · National Cancer Institute (NCI) (6) · Mari Dallas (2) · Federal Research Institute of Pediatric Hematology, Oncology and Immunology (2) · University of Bergen (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · National Eye Institute (NEI) (1) · Shanghai Public Health Clinical Center (1)
What is being tested here
Drugs under test in Opportunistic Infections studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Sintilimab | 1 | 0 | 1 |
| Mycophenolic Acid | 0 | 1 | 2 |
| Antilymphocyte Serum | 0 | 0 | 1 |
| Busulfan | 0 | 0 | 1 |
| Prednisone | 0 | 0 | 1 |
| Cyclophosphamide | 0 | 0 | 1 |
| Mesna | 0 | 0 | 1 |
| Tacrolimus | 0 | 0 | 1 |
| Pentostatin | 0 | 0 | 1 |
| Zidovudine | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Nov 2026A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia · National Institute of Allergy and Infectious Diseases (NIAID)
- Jun 2027Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma · National Cancer Institute (NCI)
- Aug 2027T Cell Therapy of Opportunistic Cytomegalovirus Infection · Mari Dallas
Who these studies take
Of the 8 Opportunistic Infections studies recruiting now, 5 (63%) set no upper age limit and 3 (38%) stop at 75 or younger. 5 (63%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (63%) | 5 (63%) |
| 18 | 8 (100%) | 8 (100%) |
| 30 | 8 (100%) | 8 (100%) |
| 40 | 8 (100%) | 8 (100%) |
| 50 | 8 (100%) | 8 (100%) |
| 65 | 8 (100%) | 8 (100%) |
| 75 | 7 (88%) | 7 (88%) |
| 85 | 5 (63%) | 5 (63%) |
Across all 41 studies, recruiting or not: 20% stop at 75 or younger and 12% at 65; 51% take children; 0% are for women only and 0% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 41 of 41. search them.
- Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaRecruitingNCT008672691 country
- Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV InfectionRecruitingNCT007890091 country
- Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ImmunityRecruitingNCT04339777Phase 21 country
- Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesRecruitingNCT02579967Phase 21 country
- A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 LymphopeniaRecruitingNCT05600920Phase 1/21 country
- Metagenomic Sequencing Across the Infectious Disease Risk and Care ContinuumNot yet recruitingNCT07825714
- Liposomal Amphotericin B for Invasive Fungal Disease in Solid Organ Transplant RecipientsNot yet recruitingNCT076564931 country
- Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell TransplantationRecruitingNCT03378102Early Phase 11 country
- Efficacy and Safety of Immune Checkpoint Inhibitors for Refractory Opportunistic Infections in AIDSNot yet recruitingNCT07579247Phase 1/21 country
- T Cell Therapy of Opportunistic Cytomegalovirus InfectionRecruitingNCT02982902Early Phase 11 country
- Brain Abscesses in Transplant Recipients: a Multicentre Retrospective Study (BAT-STUDY)Not yet recruitingNCT06242496
- Vicente Ferrer HIV Cohort StudyRecruitingNCT024545691 country
- Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell LymphomaActive, not recruitingNCT03922724Phase 21 country
- Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gammaActive, not recruitingNCT008148273 countries
- Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingNCT03663933Phase 21 country
- Re-engagement at Discharge 2CompletedNCT05694546Not applicable1 country
- Making an Early Diagnosis of Talaromycosis Using a Novel Antigen TestCompletedNCT040331201 country
- Trends of Morbidity and Mortality Among Thai HIV-infected and HIV-uninfected Patients: a Five-year Prospective Cohort StudyCompletedNCT016344771 country
- Treatment of Cytomegalovirus (CMV) Infections With Viral-Specific T CellsTerminatedNCT03798301Phase 11 country
- CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCTCompletedNCT02942173Phase 2/31 country
- Evaluation of Reporting of Antibody-Drug Conjugate Associated Sepsis-related ToxicitiesCompletedNCT053493831 country
- Inflammation and Co-Infections in D²EFTWithdrawnNCT04183738Phase 4
- Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART CentreCompletedNCT039930931 country
- Central Nervous System Disease in HIV-infected Children on HAARTCompletedNCT001103311 country
- Immune Reconstitution Syndrome in HIV-Infected Patients Taking Antiretroviral TherapyCompletedNCT002867672 countries
- Impact of Cotrimoxazole Use in Immunocompetent HIV Patients on Carriage of Antimicrobial Resistant BacteriaCompletedNCT03087890Phase 41 country
- Evaluation and Monitoring of Patients With HIV InfectionnCompletedNCT005575701 country
- Validation of a Risk Score Opportunistic Infections Development in Kidney Transplant PatientsCompletedNCT030837561 country
- Tecfidera Lymphocyte Chart ReviewCompletedNCT025194131 country
- Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell TransplantationCompletedNCT02337595Phase 1/21 country
- Prediction and Pathogenesis of the Immune Reconstitution Inflammatory SyndromeCompletedNCT015578031 country
- Antiretroviral Therapy for Advanced HIV Disease in South AfricaCompletedNCT00342355Phase 41 country
- Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected PersonsCompletedNCT00463086Not applicable1 country
- A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment OutcomesStatus unknownNCT01541631Not applicable1 country
- Immunosuppressive Therapy With Certican (Everolimus) After Lung TransplantationCompletedNCT00402532Phase 31 country
- A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected PatientsCompletedNCT00398996Phase 31 country
- Genetics of Progressive Multifocal Leukoencephalopathy and Acquired Immunodeficiency SyndromeCompletedNCT003426021 country
- Cotrimoxazole Prophylaxis Cessation Study Among Stabilized HIV-Infected Adult Patients on HAART in Entebbe, UgandaStatus unknownNCT00674921Phase 41 country
- Immune Activity Against CVM RetinitisCompletedNCT000016111 country
- Monitoring Patients for Developing Communicable and Opportunistic Infections and for Responding to TherapyCompletedNCT000014771 country
- Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate ResistanceCompletedNCT00137657Phase 41 country