Neuroectodermal Tumors, Primitive: all 120 studies

Page 1 of 2. Open to participants first (22), then studies with results posted, then the rest; newest registration first within each.

• Adjuvant Trial in Pancreatic Neuroendocrine TumorsNot yet recruitingNCT07591493Phase 3
• B7-H3.CD28Z.CART in CNS NeoplasmsRecruitingNCT07390539Phase 1
• Superb Microvascular Imaging (SMI) and Two-Dimensional Endoscopic Ultrasound Guided Shear Wave Elastography (2D-SWE-EUS) in Differential Diagnosis of Pancreatic Adenocarcinoma (PA) From Other Pancreatic Solid Lesions (PSLs) and Pancreatic neuroendocrinE Tumors (pNETs) MalignancyRecruitingNCT07274657Not applicable
• Intermediate-Size Cohort EAP for Ersodetug in Patients With Inadequately Controlled Hypoglycemia Related to a TumorAvailableNCT07262970
• Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL TrialRecruitingNCT07167329Phase 2
• Risk Factors, Prognosis, Clinicopathological and Metabolic Characteristics of EO- vs LO-PanNETsRecruitingNCT07136701
• GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young AdultsRecruitingNCT07087002Phase 1
• Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post ConsolidationRecruitingNCT06942039Early Phase 1
• A Phase 3 Study of Ersodetug in Patients With Tumor HyperinsulinismRecruitingNCT06881992Phase 3
• Embryonal Tumor With Multilayered RosettesRecruitingNCT06861244Phase 2
• A Study of HS-10516 in Patients With VHL Syndrome Associated TumorsRecruitingNCT06553339Phase 1
• Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasRecruitingNCT06465199Phase 1/2
• Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)RecruitingNCT06193759Phase 1
• Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain CancerRecruitingNCT05106296Phase 1
• ETMR One: An International Registry and Research Platform for Children With Embryonal Tumor With Multilayer RosettesRecruitingNCT04794686
• Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System TumorsRecruitingNCT04185038Phase 1
• C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)RecruitingNCT04099797Phase 1
• Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine TumorsRecruitingNCT04074135Phase 2
• HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 1
• An Intermediate Expanded Use Trial of DFMOAvailableNCT03581240
• Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 PatientsRecruitingNCT03048266
• Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid TumorsRecruitingNCT02508038Phase 1
• Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)CompletedNCT02955069Phase 2Results posted
• Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)TerminatedNCT02624388Phase 2Results posted
• A Multi-Center, Open-Label Study of Surufatinib (HMPL-012) in Patients With Advanced Solid TumorsCompletedNCT02549937Phase 1/2Results posted
• A Study to Assess the Safety and the Efficacy of the Combination of TH-302 and Sunitinib in Neuroendocrine Pancreatic TumoursCompletedNCT02402062Phase 2Results posted
• Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETsTerminatedNCT02332889Phase 1/2Results posted
• Molecular-Guided Therapy for Childhood CancerCompletedNCT02162732Not applicableResults posted
• A Ph 2 Study of Fosbretabulin in Subjects w Pancreatic or Gastrointestinal Neuroendocrine Tumors w Elevated BiomarkersCompletedNCT02132468Phase 2Results posted
• Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid TumorsCompletedNCT02095132Phase 1/2Results posted
• Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade GliomaCompletedNCT01977677Phase 1/2Results posted
• BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy.CompletedNCT01658436Phase 2Results posted
• Efficacy and Safety of BEZ235 Compared to Everolimus in Patients With Advanced Pancreatic Neuroendocrine TumorsTerminatedNCT01628913Phase 2Results posted
• Efficacy of Everolimus Alone or in Combination With Pasireotide LAR in Advanced PNETTerminatedNCT01374451Phase 2Results posted
• Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal TumorCompletedNCT01326104Phase 2Results posted
• Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of ChemotherapyCompletedNCT01222767Phase 2Results posted
• Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal TumorsCompletedNCT01217437Phase 2Results posted
• Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine OriginTerminatedNCT00958841Phase 2Results posted
• Bevacizumab and Lapatinib in Children With Recurrent or Refractory EpendymomaCompletedNCT00883688Phase 2Results posted
• A Five-Tier, Open-Label Study of IMC-A12 in Advanced SarcomaCompletedNCT00668148Phase 2Results posted
• Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 3Results posted
• Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal CancerCompletedNCT00445965Phase 2Results posted
• Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain TumorsCompletedNCT00369785Phase 3Results posted
• Antineoplaston Therapy in Treating Children With Primitive Neuroectodermal TumorsCompletedNCT00003460Phase 2Results posted
• Antineoplaston Therapy in Treating Children With Brain TumorsCompletedNCT00003458Phase 2Results posted
• Antineoplaston Therapy in Treating Patients With Brain TumorsCompletedNCT00003457Phase 2Results posted
• Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 2
• 131I-omburtamab for the Treatment of Central Nervous System/Leptomeningeal Neoplasms in Children and Young AdultsNo longer availableNCT05064306
• Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsActive, not recruitingNCT04541082Phase 1
• Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain CancerWithdrawnNCT04521946Phase 1
• EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS TumorsCompletedNCT03638167Phase 1
• HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS TumorsActive, not recruitingNCT03500991Phase 1
• Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and SarcomasActive, not recruitingNCT03478462Phase 1
• SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsCompletedNCT03434262Phase 1
• Rare CNS Tumors Outcomes &RiskCompletedNCT03251989
• Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)Status unknownNCT03053999
• Overall and Disease Specific Survival in Patients With Confirmed MEN1 With or Without PNET (Pancreatic Neuroendocrine Tumors)Active, not recruitingNCT03043508
• Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain MetastasesTerminatedNCT02967380Not applicable
• Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETsTerminatedNCT02943733Phase 1
• Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's SarcomaCompletedNCT02736565Phase 1
• Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain TumorsTerminatedNCT02684071Phase 2
• HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain TumorsCompletedNCT02457845Phase 1
• Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain TumorsCompletedNCT02444546Phase 1
• Capecitabine ON Temozolomide Radionuclide Therapy Octreotate Lutetium-177 NeuroEndocrine Tumours StudyCompletedNCT02358356Phase 2
• Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 1CompletedNCT02355535Phase 1
• Multicenter Register for Children and Young Adults With Intracranial Localized Medulloblastoma, CNS-PNET or EpendymomaCompletedNCT02238899
• Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain TumorsWithdrawnNCT02194452Not applicable
• Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or LymphomaTerminatedNCT02110563Phase 1
• NAC to Prevent Cisplatin-induced Hearing LossCompletedNCT02094625Phase 1
• International Society of Paediatric Oncology (SIOP) PNET 5 MedulloblastomaActive, not recruitingNCT02066220Phase 2/3
• p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System TumorsCompletedNCT01975116Phase 1
• A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed MedulloblastomaActive, not recruitingNCT01878617Phase 2
• Valproic Acid in Childhood Progressive Brain TumorsWithdrawnNCT01861990Phase 1
• Photodynamic Therapy (PDT) for Recurrent Pediatric Brain TumorsCompletedNCT01682746Phase 1
• Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid TumorsCompletedNCT01661400Phase 1
• Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System TumorsCompletedNCT01445288
• Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine TumorsStatus unknownNCT01381822Phase 1
• A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research PurposesTerminatedNCT01251913
• Yoga Therapy in Treating Patients With Malignant Brain TumorsTerminatedNCT01234805Not applicable
• RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant GliomaCompletedNCT01119599Phase 1
• A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With GliomasWithdrawnNCT01117155
• Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2CompletedNCT01082926Phase 1
• Study of Blood and Cheek Cell Samples From Patients With GliomaCompletedNCT01009307
• A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS TumorsCompletedNCT00994071Phase 1
• Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell TumorsStatus unknownNCT00983398Phase 1/2
• Study of Tissue Samples From Patients With Glioma or Other Brain TumorsCompletedNCT00967200
• Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Clinical TrialCompletedNCT00890435
• A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain TumorsCompletedNCT00784914Phase 1
• Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain TumorsCompletedNCT00629889Phase 2
• Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer SyndromeCompletedNCT00565903
• QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell TumorsCompletedNCT00563680Phase 2
• Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to TreatmentCompletedNCT00544284Phase 1
• Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain TumorsCompletedNCT00499798
• Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain DisordersCompletedNCT00255671
• High Risk Primitive Neuroectodermal (PNET) Brain Tumors in ChildhoodStatus unknownNCT00180791Phase 2
• Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain TumorsTerminatedNCT00110032Phase 1
• Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain TumorCompletedNCT00070161Phase 2
• Thalidomide and Docetaxel in Treating Patients With Advanced CancerCompletedNCT00049296Phase 1
• CC-5013 in Treating Patients With Recurrent GliomaCompletedNCT00036894Phase 1
• Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain TumorsTerminatedNCT00031798Phase 3

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