Mesothelioma, Malignant: all 418 studies
Page 1 of 5. Open to participants first (73), then studies with results posted, then the rest; newest registration first within each.
- Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural MesotheliomaNot yet recruitingNCT07885319Phase 1/2
- A Phase 3 Trial in Advanced Epithelioid MesotheliomaNot yet recruitingNCT07824986Phase 3
- TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid TumorsRecruitingNCT07713732Phase 1
- Multidimensional Omics Analysis in Malignant Pleural MesotheliomaRecruitingNCT07561190
- Comprehensive Oncogenomic Mapping and Exploration in Thoracic and Head & Neck OncologyNot yet recruitingNCT07550049
- Dual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal MesotheliomaRecruitingNCT07510815Phase 1/2
- Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary TumorsRecruitingNCT07443020Phase 1
- INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP)RecruitingNCT07403630Not applicable
- Study of TYK-01054 Capsules in Patients With Advanced Solid TumorsNot yet recruitingNCT07282873Phase 1/2
- A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsRecruitingNCT07277413Phase 1
- Trial Assessing Fianlimab Plus Cemiplimab Plus Chemotherapy or Cemiplimab Plus Chemotherapy in Patients With Pleural MesotheliomaRecruitingNCT07234058Phase 2
- Fast TILs to Treat Metastatic Cancer Patients With Pleural DiseaseRecruitingNCT07192900Phase 1
- Study of Iparomlimab and Tuvonralimab Plus Chemotherapy in Malignant MesotheliomaNot yet recruitingNCT07131345Phase 1/2
- Partial Pleurectomy (Surgery) for Unresectable Pleural MesotheliomaRecruitingNCT07126509Not applicable
- NEoadjuvant Chemotherapy and Immunotherapy for a Selected Group of Inoperable Pleural Mesothelioma Patients (NECIM): a Feasibility StudyRecruitingNCT07121374Phase 1/2
- Evaluation of Skin Tests in Biotherapy AllergiesRecruitingNCT06971848Not applicable
- First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.RecruitingNCT06946498Not applicable
- Hemithoracic Arc Radiotherapy Post Pleural DecorticationRecruitingNCT06910449Not applicable
- Genetic Susceptibility in MAlignant Pleural Mesothelioma: Clinical Implication of GermliNE VariaTionSRecruitingNCT06886672
- Multicenter Single-Arm Study of Ivonescimab (AK112) Combined with Chemotherapy in Pretreated Pleural MesotheliomaRecruitingNCT06875076Phase 2
- Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and ChemotherapyRecruitingNCT06840834Phase 2
- The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural MesotheliomaRecruitingNCT06790082Phase 2
- CT-95 in Advanced Cancers Associated With Mesothelin ExpressionRecruitingNCT06756035Phase 1
- A Study of MT027 in Patients with Pleural Malignant TumorsRecruitingNCT06726564Phase 1
- Phase 1 Dose Escalation and Expansion to Evaluate AROG4-01 in Patients With Advanced Solid TumorsNot yet recruitingNCT06652529Phase 1
- Identification of Prognostic and Predictive Biomarkers of Toxicity in Patients With Malignant Pleural Mesothelioma and Treated With High Doses of Radiotherapy (MESORTIBO)RecruitingNCT06637345
- Using CICS-1 and SPM-011 and ［18F］FBPA Commissioned by CICS and Sumitomo Heavy Industries and STELLA PHARMAEnrolling by invitationNCT06603987Phase 1/2
- Study of ISM6331 in Participants With Advanced/Metastatic Mesothelioma or Other Advanced Solid TumorsRecruitingNCT06566079Phase 1/2
- Sintilimab, Bevacizumab, Pemetrexed, and Cisplatin for Unresectable MPeMRecruitingNCT06543069Phase 2
- New Preclinical and Clinical Approaches to MesotheliomaRecruitingNCT06536179
- EXTRA-Meso (EXercise TheRApy in Mesothelioma) FeasibilityRecruitingNCT06491784Not applicable
- A Study of Sacituzumab Govitecan in People With MesotheliomaRecruitingNCT06477419Phase 2
- Ga-68 FAPI PET Before ImmunotherapyRecruitingNCT06451536Not applicable
- Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural MesotheliomaNot yet recruitingNCT06416930Phase 2
- Evaluation of Response by FLT PET in MesotheliomaRecruitingNCT06410625Not applicable
- A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab MonotherapyRecruitingNCT06362369Phase 1/2
- Exercise to Boost Immunity in Advanced CancerNot yet recruitingNCT06310993Not applicable
- Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin AdministrationRecruitingNCT06281860Phase 1
- Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid TumorsRecruitingNCT06256055Phase 1
- SW-682 in Advanced Solid TumorsRecruitingNCT06251310Phase 1
- A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal MesotheliomaRecruitingNCT06057935Phase 2
- A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionRecruitingNCT06051695Phase 1/2
- Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural MesotheliomaRecruitingNCT06037941Not applicable
- Oncolytic Adenovirus(H101) Combined With PD-1 Inhibitors in Patients With Advanced Malignant Pleural MesotheliomaRecruitingNCT06031636
- Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage MesotheliomaRecruitingNCT05960773Phase 2
- HTL0039732 in Participants With Advanced Solid TumoursRecruitingNCT05944237Phase 1/2
- Study of Cadonilimab Combined With Bevacizumab and Standard Chemotherapy as First Line Therapy in Unresectable Pleural MesotheliomaRecruitingNCT05930665Phase 2
- Studying the Clinical Trial Experiences of Patients With MesotheliomaNot yet recruitingNCT05819580
- Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural MesotheliomaRecruitingNCT05765084Phase 1/2
- Clinical Study to Evaluate Safety and Dosing of CA9hu-1 in Patients With Advanced Solid TumoursNot yet recruitingNCT05698238Phase 1
- Hemithoracic Irradiation With Proton Therapy in Malignant Pleural MesotheliomaRecruitingNCT05655078Not applicable
- TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVORecruitingNCT05628376
- First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor MalignanciesRecruitingNCT05627960Phase 1
- SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or MesotheliomaRecruitingNCT05568680Phase 1
- TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma StudyRecruitingNCT05538806
- AMT-151 in Patients With Selected Advanced Solid TumoursRecruitingNCT05498597Phase 1
- OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint InhibitionNot yet recruitingNCT05425576Phase 2
- dENdritic Cell Therapy Combined With SURgEry in MesotheliomaRecruitingNCT05304208Phase 1
- First Line Sintilimab Combined With Anlotinib and Platinum Doublet Chemotherapy in Malignant Pleural MesotheliomaRecruitingNCT05188859Phase 2
- A Study of NX-1607 in Adults With Advanced MalignanciesRecruitingNCT05107674Phase 1
- A Beta-only IL-2 ImmunoTherapY StudyRecruitingNCT05086692Phase 1/2
- Atezolizumab Versus Placebo for the Adjuvant Treatment of Malignant Pleural Mesothelioma (Atezomeso)RecruitingNCT04996017Phase 3
- Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingRecruitingNCT04981119
- TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural MesotheliomaRecruitingNCT04969315Phase 1/2
- Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural MesotheliomaRecruitingNCT04823741
- Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural MesotheliomaNot yet recruitingNCT04713761Phase 2
- Olaparib in Patients With HRD Malignant MesotheliomaRecruitingNCT04515836Phase 2
- The IMmunotherapy Pleural 5-ALA PDTRecruitingNCT04400539Phase 2
- A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and LymphomasRecruitingNCT04104776Phase 1/2
- APG-2449 in Patients With Advanced Solid TumorsRecruitingNCT03917043Phase 1
- Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)RecruitingNCT03760575Phase 1
- A Phase I/II Study of Regorafenib Plus Avelumab in Solid TumorsRecruitingNCT03475953Phase 1/2
- Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung LiningRecruitingNCT00242723
- A Study to Investigate 14C-bemcentinib in Healthy Male SubjectsCompletedNCT06469138Phase 1Results posted
- NUC-3373 in Combination With Other Agents in Patients With Advanced Solid TumoursTerminatedNCT05714553Phase 1/2Results posted
- A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing CancerTerminatedNCT05451849Phase 1/2Results posted
- A Study of Immunotherapy Drugs Nivolumab and Ipilimumab in Patients w/Resectable Malignant Peritoneal MesotheliomaCompletedNCT05041062Phase 2Results posted
- Study of the Efficacy and Safety of the Bintrafusp Alfa in Previously Treated Advanced Malignant Pleural MesotheliomaCompletedNCT05005429Phase 2Results posted
- A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)TerminatedNCT04914897Phase 2Results posted
- Alvopem® (Pemetrexed) Safety AssessmentCompletedNCT04843007Results posted
- Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant MesotheliomaTerminatedNCT04840615Phase 1Results posted
- DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural MesotheliomaCompletedNCT04334759Phase 3Results posted
- Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural MesotheliomaTerminatedNCT04158141Phase 3Results posted
- Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural MesotheliomaCompletedNCT03710876Phase 3Results posted
- Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant MesotheliomaCompletedNCT03654833Phase 2Results posted
- Anti-Mesothelin Immunotoxin LMB-100 Followed by Pembrolizumab in Malignant MesotheliomaTerminatedNCT03644550Phase 2Results posted
- Olaparib in People With Malignant MesotheliomaCompletedNCT03531840Phase 2Results posted
- Phase II Nivolumab and Ramucirumab for Patients With Previously-Treated MesotheliomaTerminatedNCT03502746Phase 2Results posted
- Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal MesotheliomaTerminatedNCT03436732Phase 1Results posted
- Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant MesotheliomaCompletedNCT03399552Phase 1/2Results posted
- Pevonedistat Alone and in Combination With Chemotherapy in Patients With MesotheliomaTerminatedNCT03319537Phase 1/2Results posted
- Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal CarcinomasTerminatedNCT03233724Phase 1/2Results posted
- Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant MesotheliomaActive, not recruitingNCT03228537Phase 1Results posted
- A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)CompletedNCT03207347Phase 2Results posted
- Evaluation of CRS-207 With Pembrolizumab in Previously Treated Malignant Pleural Mesothelioma (MPM)TerminatedNCT03175172Phase 2Results posted
- Pembrolizumab With or Without Anetumab Ravtansine in Treating Patients With Mesothelin-Positive Pleural MesotheliomaActive, not recruitingNCT03126630Phase 1/2Results posted
- CAR T Cells in Mesothelin Expressing CancersCompletedNCT03054298Phase 1Results posted
- Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant MesotheliomaCompletedNCT02959463Phase 1Results posted
- Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma PatientsCompletedNCT02899299Phase 3Results posted
- Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable MesotheliomaCompletedNCT02899195Phase 2Results posted