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Macrophage Activation Syndrome clinical trials

The registry lists 20 studies for Macrophage Activation Syndrome across more than 10 countries. 4 are recruiting or about to start. 10 of them are mainly about Macrophage Activation Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
8
Active, not recruiting
4
Status unknown
3
Not yet recruiting
2
Recruiting
2
Terminated
1

Phase

Phase 2
7
Phase 1
4
Phase 3
2

Where

United States
9
Italy
5
France
5
Spain
3
Netherlands
2
Greece
2

Who runs them

Swedish Orphan Biovitrum (5) · Hellenic Institute for the Study of Sepsis (2) · Diane George (2) · National Cancer Institute (NCI) (1) · Gunnar Lachmann (1) · Peking University People's Hospital (1) · Amrita Institute of Medical Sciences & Research Center (1) · Meyer Children's Hospital IRCCS (1)

What is being tested here

Drugs under test in Macrophage Activation Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Interleukin 1 Receptor Antagonist Protein004
Emapalumab012
Melphalan001
Busulfan001
Fludarabine001
Tocilizumab001
Ruxolitinib011
Methylprednisolone011
Interleukin-2001

Coming up

0phase 3 studies under way
2studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2

Who these studies take

Of the 2 Macrophage Activation Syndrome studies recruiting now, 1 (50%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 2
AgeWomenMen
100 (0%)0 (0%)
182 (100%)2 (100%)
302 (100%)2 (100%)
402 (100%)2 (100%)
502 (100%)2 (100%)
652 (100%)2 (100%)
752 (100%)2 (100%)
852 (100%)2 (100%)

Across all 20 studies, recruiting or not: 25% stop at 75 or younger and 20% at 65; 70% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 15, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 20 of 20. search them.