Lymphopenia clinical trials
The registry lists 44 studies for Lymphopenia across more than 10 countries. 8 are recruiting or about to start. 9 of them are mainly about Lymphopenia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27. Counting its narrower condition Wiskott-Aldrich Syndrome too: 85 studies, 11 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Revimmune (6) · ImmunityBio, Inc. (4) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3) · Centre Leon Berard (2) · TRPHARM (2) · Second Affiliated Hospital of Soochow University (2) · Hospices Civils de Lyon (2) · Centre Hospitalier Universitaire de Saint Etienne (2)
What is being tested here
Drugs under test in Lymphopenia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma · John Flickinger
- Dec 2026PRaG-1 Plus PRaG Therapy in in Elderly Patients With Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0) · Second Affiliated Hospital of Soochow University
- Jul 2027Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After Chemoradiation · M.D. Anderson Cancer Center
- Aug 2027NAI for Sepsis With Persistent Lymphopenia · ImmunityBio, Inc.
- Nov 2027Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological Tumors · The First Affiliated Hospital of Xiamen University
Who these studies take
Of the 6 Lymphopenia studies recruiting now, 5 (83%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 6 (100%) | 6 (100%) |
| 30 | 6 (100%) | 6 (100%) |
| 40 | 6 (100%) | 6 (100%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 6 (100%) | 6 (100%) |
Across all 44 studies, recruiting or not: 7% stop at 75 or younger and 7% at 65; 11% take children; 5% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
Studies
Recruiting first, then most recently updated. Showing 44 of 44. search them.
- PRaG-1 Plus PRaG Therapy in in Elderly Patients With Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0)RecruitingNCT07267234Phase 21 country
- Serologic Response to Pneumococcal Vaccination Among Esophageal Cancer Patients With High Grade Lymphopenia After ChemoradiationRecruitingNCT061816561 country
- NAI for Sepsis With Persistent LymphopeniaNot yet recruitingNCT07578558Phase 2
- Evaluation of the Effect of Cordycepin on CD8+ Lymphocytopenia in Patients With Solid TumorsRecruitingNCT07258160Phase 21 country
- Expanded Access Use of Nogapendekin-alfa Inbakicept in the Reversal and Maintenance of Absolute Lymphocyte Count (ALC) for the Treatment of Lymphopenia Induced by Chemotherapy, Immunotherapy, and/or Radiation TherapyAvailableNCT069565471 country
- Immunological Effects of Iron Supplementation in HHT DiseaseRecruitingNCT07111598Not applicable1 country
- Methylprednisolone for Stroke With Large Infarct Core and Post-stroke LymphocytopeniaRecruitingNCT07202143Phase 31 country
- Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological TumorsRecruitingNCT06584006Phase 21 country
- RSV, Influenza, and SARS-CoV-2 Outcomes in Severely Immunosuppressed AdultsActive, not recruitingNCT07816471
- COVID-19 Associated Lymphopenia Pathogenesis Study in BloodCompletedNCT044014361 country
- Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS)WithdrawnNCT07492888Phase 2
- Study of Nogapendekin Alfa Inbakicept and iNKT Cells in Critically Ill Adults With Severe Community-Acquired PneumoniaWithdrawnNCT07492875Phase 3
- Thymus Dosimetric and Morphologic Predictors of Radiation-Induced Lymphopenia in Stage III NSCLCActive, not recruitingNCT075640891 country
- Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT04019262Phase 1/21 country
- Donor Stem Cell Boost in Treating Patients With Low Blood Cells After Donor Stem Cell TransplantWithdrawnNCT01660347Not applicable
- CD8+ T-cell PET/CT Imaging in COVID-19 PatientsTerminatedNCT048748181 country
- Persistent Lymphopenia in Liver Transplantation and Its Molecular Insights for Hepatocellular CarcinomaCompletedNCT063683491 country
- InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort)TerminatedNCT04927169Phase 21 country
- InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O )TerminatedNCT04426201Phase 21 country
- A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19CompletedNCT04646044Phase 11 country
- Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade GliomasTerminatedNCT02659800Phase 11 country
- Stroke-induced Immunodepression in NeurorehabilitationCompletedNCT058891691 country
- Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 InfectionTerminatedNCT04487444Phase 21 country
- Study of Lymphopenia as a Specific Biomarker or Prognostic Risk Factor for Disease Severity in Elderly Patients With COVID-19CompletedNCT048007311 country
- Etiology of Lymphopenia in Covid19 InfectionCompletedNCT044046081 country
- InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection FR BL CohortTerminatedNCT04407689Phase 21 country
- InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection ( ILIAD-7-US-I )TerminatedNCT04442178Phase 21 country
- InterLeukin-7 (CYT107) to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection UK CohortTerminatedNCT04379076Phase 21 country
- Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin EStatus unknownNCT053003731 country
- Investigation of ADA Enzyme DeficiencyStatus unknownNCT053003341 country
- Nicotinamide-based Supportive Therapy in Lymphopenia for Patients With COVID-19CompletedNCT04910230Not applicable1 country
- Recombinant Interleukin-7 (CYT107) to Restore Absolute Lymphocyte Counts in Sepsis PatientsTerminatedNCT03821038Phase 22 countries
- Assessment of Postoperative Lymphopenia as Risk Factor for Postoperative InfectionsCompletedNCT027992511 country
- Expression of the Inhibitory Receptors on Lymphocytes T Cells After Lung Cancer Surgery.CompletedNCT03549546Not applicable1 country
- Feasibility of Lymphocyte Reinfusion in Newly Diagnosed High Grade GliomasCompletedNCT01653834Not applicable1 country
- Research Into the Molecular Bases of a New Phenotype Combining Premature White Hair, Polycystic Kidney Disease, Aortic Dilation/Dissection and LymphopeniaCompletedNCT036513881 country
- Study of Drug to Reduce Thrombocytopenia in Patients Receiving Chemo for Ovarian, Fallopian Tube or Peritoneal CancerCompletedNCT00771810Phase 21 country
- A Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade GliomaCompletedNCT02490930Early Phase 11 country
- Evaluation of Immunosuppression in Septic Shock: Biomarkers and Pharmacological Restoration (IMMUNOSEPSIS)Status unknownNCT028033461 country
- Lymphocyte Count as a Sign of Immunoparalysis and Its Correlation With Nutritional Status in Septic Pediatric PatientsCompletedNCT02698683
- Prognostic Value of Divpenia and CD4 Count in Relapsed Breast or Lung Cancer PatientsCompletedNCT013061881 country
- Study Evaluating Impact of IL-7 on CD4 Lymphopenia, Risks of Severe Haematological Toxicity and Tumor Progression in Metastatic Breast Cancer PatientsCompletedNCT01368107Phase 21 country
- Safety Study of IL-7 in HIV-infected Patients (Inspire)CompletedNCT00477321Phase 14 countries
- Safety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell TransplantCompletedNCT00684008Phase 11 country