Lymphangioma clinical trials
The registry lists 13 studies for Lymphangioma across more than 10 countries. 5 are recruiting or about to start. 7 of them are mainly about Lymphangioma (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-09.
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Palvella Therapeutics, Inc. (2) · Sohag University (1) · National Children's Hospital, Vietnam (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Yonsei University (1) · University of Iowa (1) · New Mexico Cancer Research Alliance (1) · Novartis Pharmaceuticals (1)
What is being tested here
Drugs under test in Lymphangioma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Alpelisib | 2 | 1 | 2 |
| Everolimus | 1 | 0 | 1 |
| Mirdametinib | 1 | 0 | 1 |
| Sirolimus | 0 | 0 | 1 |
| Sirolimus Topical Gel PTX-022 | 0 | 0 | 1 |
| Sildenafil | 0 | 0 | 1 |
| Picibanil | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Jan 2027A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations · Murdoch Childrens Research Institute
Who these studies take
Of the 4 Lymphangioma studies recruiting now, 1 (25%) set no upper age limit and 1 (25%) stop at 75 or younger. 4 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (100%) | 4 (100%) |
| 18 | 3 (75%) | 3 (75%) |
| 30 | 3 (75%) | 3 (75%) |
| 40 | 3 (75%) | 3 (75%) |
| 50 | 3 (75%) | 3 (75%) |
| 65 | 3 (75%) | 3 (75%) |
| 75 | 3 (75%) | 3 (75%) |
| 85 | 3 (75%) | 3 (75%) |
Across all 13 studies, recruiting or not: 38% stop at 75 or younger and 38% at 65; 92% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 13 of 13. search them.
- Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.RecruitingNCT05948943Phase 2/312 countries
- A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular MalformationsRecruitingNCT05983159Phase 21 country
- A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular AnomaliesNot yet recruitingNCT07477548Phase 2
- Institution of an Italian Registry and Biobank for Biological Sample CollectionRecruitingNCT06892964Not applicable1 country
- Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular MalformationsRecruitingNCT061607391 country
- SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic MalformationsActive, not recruitingNCT06239480Phase 31 country
- Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesCompletedNCT00975819Phase 21 country
- Bleomycin as an Effective and Curative Adjunct Therapy for LymphangiomaCompletedNCT069437031 country
- Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic MalformationsCompletedNCT05050149Phase 21 country
- Clinical Characteristics of Lymphatic MalformationsCompletedNCT062577191 country
- Compassionate Use of BYL 719 AlpelisibNo longer availableNCT039417821 country
- A Study to Evaluate Sildenafil for the Treatment of Lymphatic MalformationsCompletedNCT01290484Phase 1/21 country
- Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic MalformationsCompletedNCT00010452Phase 2/31 country