Leukemia, Myeloid, Chronic-Phase clinical trials
The registry lists 439 studies for Leukemia, Myeloid, Chronic-Phase across more than 10 countries. 27 are recruiting or about to start. 61 of them are mainly about Leukemia, Myeloid, Chronic-Phase (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Fred Hutchinson Cancer Center (45) · M.D. Anderson Cancer Center (26) · National Cancer Institute (NCI) (18) · City of Hope Medical Center (18) · Memorial Sloan Kettering Cancer Center (15) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (14) · Roswell Park Cancer Institute (13) · OHSU Knight Cancer Institute (12)
What is being tested here
Drugs under test in Leukemia, Myeloid, Chronic-Phase studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Asciminib | 3 | 1 | 6 |
| Flumatinib | 3 | 0 | 4 |
| Relcobatinib | 3 | 1 | 3 |
| Embibatinib | 3 | 0 | 3 |
| Ponatinib | 2 | 1 | 6 |
| Cyclophosphamide | 1 | 1 | 48 |
| Busulfan | 1 | 1 | 33 |
| Dasatinib | 1 | 4 | 24 |
| Melphalan | 1 | 1 | 14 |
| Nilotinib | 1 | 1 | 14 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 15 open · Alkylating agents 1 open · Antimetabolites 1 open · Calcineurin inhibitors 34 · Corticosteroids 13
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7, phase 3 first
- Jun 2027Study of Olverembatinib (HQP1351) in Patients With CML-CP · Phase 3 · Ascentage Pharma Group Inc.
- Jun 2027A Phase 3 Study for the Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIs · Phase 3 · Il-Yang Pharm. Co., Ltd.
- Apr 2027A Real World Study of the Efficacy and Safety of Flumatinib Versus Imatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase · Jiangsu Hansoh Pharmaceutical Co., Ltd.
- May 2027MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing · Medical College of Wisconsin
- May 2027Personalized NK Cell Therapy in CBT · M.D. Anderson Cancer Center
- Jun 2027Evaluation of Advanced Practice Nurse's Management of Patients With Chronic Myeloid Leukemia · Centre Hospitalier Henri Duffaut - Avignon
- Jul 2027A Study of Patient Characteristics, Co-Morbidities, and Treatment Patterns in Chronic Myeloid Leukemia Patients in Kuwait · Novartis Pharmaceuticals
Who these studies take
Of the 20 Leukemia, Myeloid, Chronic-Phase studies recruiting now, 13 (65%) set no upper age limit and 5 (25%) stop at 75 or younger. 3 (15%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (10%) | 2 (10%) |
| 18 | 17 (85%) | 17 (85%) |
| 30 | 17 (85%) | 17 (85%) |
| 40 | 17 (85%) | 17 (85%) |
| 50 | 17 (85%) | 17 (85%) |
| 65 | 18 (90%) | 18 (90%) |
| 75 | 16 (80%) | 16 (80%) |
| 85 | 14 (70%) | 14 (70%) |
Across all 439 studies, recruiting or not: 38% stop at 75 or younger and 25% at 65; 43% take children; 0% are for women only and <1% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Leukemia, Myeloid, Chronic-Phase studies take
Of 49 phase 2 interventional studies under Leukemia, Myeloid, Chronic-Phase, half reached primary completion within 70 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 70 mo43–132 · 49 studies | — | 84 mo44–153 · 42 studies |
| Observational | 35 mo31–59 · 13 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 439. Browse all 439 → or search them.
- A Study of Patient Characteristics, Co-Morbidities, and Treatment Patterns in Chronic Myeloid Leukemia Patients in KuwaitNot yet recruitingNCT07454850
- Personalized NK Cell Therapy in CBTRecruitingNCT02727803Phase 21 country
- A Randomized Study of ELVN-001 Versus Investigator-Selected TKI, in CP-CML Previously Treated With One or More TKIsNot yet recruitingNCT07905183Phase 3
- A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell TransplantRecruitingNCT07020533Phase 11 country
- A Clinical Study of MK-4208/TERN-701 in Participants With Chronic Myeloid Leukemia (CML) (MK-4208-003/Tern701-1012/CARDINAL)RecruitingNCT06163430Phase 1/29 countries
- Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid TumorsRecruitingNCT03934372Phase 1/27 countries
- Ponatinib Hydrochloride as Second Line Therapy in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase Resistant or Intolerant to Imatinib Mesylate, Dasatinib, or NilotinibRecruitingNCT01746836Phase 21 country
- Study of Olverembatinib (HQP1351) in Patients With CML-CPRecruitingNCT06423911Phase 316 countries
- A Phase 3 Study for the Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIsRecruitingNCT03459534Phase 34 countries
- Protocol Number: HJKC3-0003. Treatment Free Remission After Asciminib Based Therapy in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI DiscontinuationRecruitingNCT04838041Phase 21 country
- A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) TherapyRecruitingNCT070910191 country
- Registry of Older Patients With CancerRecruitingNCT011378251 country
- Efficacy of Asciminib in Real-world in Patients With Chronic Myeloid Leukemia in Second or Subsequent LinesNot yet recruitingNCT07640750
- MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG DosingRecruitingNCT05794880Not applicable1 country
- A Study of Treatment-free Remission in Chronic Phase Chronic Myeloid LeukemiaRecruitingNCT06368414Phase 21 country
- A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid LeukemiaRecruitingNCT05304377Phase 114 countries
- TGRX-678 Chinese Phase III in Chronic Myelogenous Leukemia (CML) PatientsNot yet recruitingNCT07489755Phase 3
- Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts w/Chronic Myeloid LeukemiaRecruitingNCT062298601 country
- Evaluation of Advanced Practice Nurse's Management of Patients With Chronic Myeloid LeukemiaRecruitingNCT06082804Not applicable1 country
- PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CMLRecruitingNCT06409936Phase 21 country
- ELVN-001 for the Treatment of Chronic Myeloid Leukemia With and Without T315I Mutation in Japanese ParticipantsRecruitingNCT06787144Phase 11 country
- Ponatinib in Chronic Myeloid Leukemia Patients in Chronic PhaseRecruitingNCT061192691 country
- Study of HS-10382 Combination in Patients With Chronic Myeloid Leukemia (CML)Not yet recruitingNCT06530810Phase 1
- Metabolic Alternation and Clinicohematological Characteristic in Chronic Phase CML in Patient Treated With TKINot yet recruitingNCT06121765
- A Study of HS-10382 in Patients With Chronic Myeloid Leukemia.RecruitingNCT05367700Phase 11 country
- A Real World Study of the Efficacy and Safety of Flumatinib Versus Imatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic PhaseNot yet recruitingNCT05367765Phase 41 country
- A Study of the Efficacy and Safety of Flumatinib in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase.RecruitingNCT05353205Phase 41 country
- Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell TransplantCompletedNCT02396134Phase 21 country
- Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell TransplantActive, not recruitingNCT011995621 country
- Study to Evaluate the Reinduction and Second Stop of TKI With Ponatinib in CML in Molecular Response (ResToP)CompletedNCT04160546Phase 21 country
- ASTX727 and Dasatinib for the Treatment of Newly Diagnosed Philadelphia Chromosome or BCR-ABL Positive Chronic Myeloid Leukemia in Chronic PhaseActive, not recruitingNCT05007873Phase 21 country
- Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid LeukemiaActive, not recruitingNCT04258943Phase 1/28 countries
- CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic TransplantActive, not recruitingNCT03560752Phase 11 country
- Therapies in Combination or Sequentially With Tyrosine Kinase Inhibitors (TKIs) in Chronic Phase Chronic Myelogenous Leukemia Patients in CCR (ACTIW)Active, not recruitingNCT02767063Phase 1/21 country
- Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual DiseaseActive, not recruitingNCT03516279Phase 21 country
- Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous LeukemiaActive, not recruitingNCT02689440Phase 21 country
- Randomized Evaluation of Radotinib Versus Imatinib in Phase III Study for Efficacy With Chinese Patients (RERISE China)Active, not recruitingNCT03722420Phase 31 country
- 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With CancerActive, not recruitingNCT009350901 country
- Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell TransplantActive, not recruitingNCT02506933Phase 21 country
- Asciminib as Initial Therapy for Patients With Chronic Myeloid Leukemia in Chronic PhaseActive, not recruitingNCT05143840Phase 21 country
- Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid LeukemiaActive, not recruitingNCT03817398Phase 24 countries
- A Study of Full Treatment-free Remission in Patients With Chronic Myeloid LeukemiaTerminatedNCT03874858Phase 21 country
- Pioglityazone and Imatinib for CML PatientsCompletedNCT02888964Phase 21 country
- Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other DisordersActive, not recruitingNCT00544115Phase 2
- Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase InhibitorsActive, not recruitingNCT03610971Phase 21 country
- Ponatinib in Participants With Resistant Chronic Phase Chronic Myeloid Leukemia (CP-CML) to Characterize the Efficacy and Safety of a Range of DosesCompletedNCT02467270Phase 221 countries
- Treatment Patterns and Key Endpoints Among Patients With Chronic-Phase Chronic Myeloid Leukemia in a Community Oncology SettingCompletedNCT073741201 country
- Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow TransplantationActive, not recruitingNCT03842696Phase 1/21 country
- Dasatinib in Treating Patients With Early Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT00254423Phase 21 country
- Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid LeukemiaActive, not recruitingNCT03654768Phase 21 country