Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative clinical trials
The registry lists 209 studies for Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative across more than 10 countries. 9 are recruiting or about to start. 16 of them are mainly about Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Fred Hutchinson Cancer Center (22) · National Cancer Institute (NCI) (18) · Case Comprehensive Cancer Center (15) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (11) · Memorial Sloan Kettering Cancer Center (10) · City of Hope Medical Center (9) · Roswell Park Cancer Institute (8) · OHSU Knight Cancer Institute (8)
What is being tested here
Drugs under test in Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ruxolitinib | 1 | 0 | 3 |
| Ropeginterferon alfa-2b | 1 | 0 | 1 |
| Axatilimab | 1 | 0 | 1 |
| Onvansertib | 1 | 0 | 1 |
| Hyperbaric Oxygen | 1 | 0 | 1 |
| Abatacept | 1 | 0 | 1 |
| Fludarabine phosphate | 0 | 1 | 24 |
| Fludarabine | 0 | 1 | 24 |
| Cyclophosphamide | 0 | 1 | 22 |
| Busulfan | 0 | 1 | 17 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open · JAK inhibitors 1 open · Antimetabolites 39 · Alkylating agents 33 · Calcineurin inhibitors 14
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7
- Dec 2026Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched Donor · St. Petersburg State Pavlov Medical University
- Jan 2027Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia · M.D. Anderson Cancer Center
- Feb 2027Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders · Memorial Sloan Kettering Cancer Center
- Mar 2027Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant · Omar Aljitawi
- Jun 2027Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms · Mayo Clinic
- Oct 2027Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia · Uma Borate
- Oct 2027Myeloproliferative Neoplasms (MPNs) Patient Registry · University Health Network, Toronto
Who these studies take
Of the 8 Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative studies recruiting now, 5 (63%) set no upper age limit and 2 (25%) stop at 75 or younger. 1 (13%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (13%) | 1 (13%) |
| 18 | 7 (88%) | 7 (88%) |
| 30 | 7 (88%) | 7 (88%) |
| 40 | 7 (88%) | 7 (88%) |
| 50 | 7 (88%) | 7 (88%) |
| 65 | 8 (100%) | 8 (100%) |
| 75 | 7 (88%) | 7 (88%) |
| 85 | 6 (75%) | 6 (75%) |
Across all 209 studies, recruiting or not: 36% stop at 75 or younger and 25% at 65; 41% take children; 0% are for women only and <1% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 209. Browse all 209 → or search them.
- Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic LeukemiaRecruitingNCT06523556Phase 1/21 country
- Ropeginterferon Alfa-2b for the Treatment of Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes and Chronic Myelomonocytic LeukemiaNot yet recruitingNCT07468916Phase 21 country
- Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic CancerRecruitingNCT011376431 country
- Therapeutic RSK1 Targeting in Myeloid MalignanciesRecruitingNCT07379125Phase 11 country
- Registry of Older Patients With CancerRecruitingNCT011378251 country
- Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap NeoplasmsRecruitingNCT05549661Phase 11 country
- Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) TransplantRecruitingNCT03964506Early Phase 11 country
- Optimization of Post-transplantation Benadamustine and Cyclophosphamide in Patients With High-risk Myeloid Malignancies and a Partially Mismatched DonorRecruitingNCT07238712Phase 21 country
- Myeloproliferative Neoplasms (MPNs) Patient RegistryRecruitingNCT027602381 country
- Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic LeukemiaActive, not recruitingNCT03289910Phase 21 country
- Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell TransplantActive, not recruitingNCT011995621 country
- 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With CancerActive, not recruitingNCT009350901 country
- Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaActive, not recruitingNCT03862157Phase 1/21 country
- Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other DisordersActive, not recruitingNCT00544115Phase 2
- Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood DisordersActive, not recruitingNCT04761770Phase 21 country
- A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid NeoplasmsTerminatedNCT04637009Phase 12 countries
- Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME TrialTerminatedNCT03878524Phase 11 country
- Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic CancerCompletedNCT00611351Phase 21 country
- Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic SyndromesCompletedNCT00045305Phase 21 country
- Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical TrialCompletedNCT008977671 country
- Sargramostim in Reducing Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplantation for Hematologic Cancer or Aplastic AnemiaCompletedNCT00053157Not applicable1 country
- Collecting and Storing Blood Samples From Patients With CancerWithdrawnNCT00900120
- Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal MetastasesCompletedNCT00424242Early Phase 11 country
- Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic CancerCompletedNCT00003816Phase 2/31 country
- Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic CancerCompletedNCT00489203Phase 21 country
- Bone Marrow Transplant in Treating Patients With Hematologic CancersCompletedNCT00005797Phase 21 country
- Ruxolitinib Phosphate in Treating Patients With Chronic Neutrophilic Leukemia or Atypical Chronic Myeloid LeukemiaCompletedNCT02092324Phase 21 country
- Arsenic Trioxide in Treating Patients With Myelodysplastic SyndromesTerminatedNCT00020969Phase 21 country
- Methadone, Morphine, or Oxycodone in Treating Pain in Patients With CancerTerminatedNCT00726830Not applicable1 country
- Voriconazole Compared With Itraconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Hematopoietic Stem Cell TransplantationCompletedNCT00079222Not applicable1 country
- Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic AnemiaCompletedNCT00054236Phase 11 country
- Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic MalignanciesCompletedNCT00068523Not applicable1 country
- Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative DisorderCompletedNCT00274820Phase 21 country
- Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical TrialCompletedNCT00750009Phase 31 country
- NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/DisordersCompletedNCT00053989Phase 21 country
- Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative DisordersCompletedNCT00397813Phase 21 country
- Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced CancerCompletedNCT00036790Phase 11 country
- Alemtuzumab Plus Fludarabine and Melphalan With or Without Cyclosporine, Mycophenolate Mofetil, and Low-Dose Total-Body Irradiation Therapy Followed by Donor Peripheral Stem Cell Transplant in Treating Patients With Hematologic CancerWithdrawnNCT00085449Phase 1/21 country
- Doxercalciferol in Treating Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic LeukemiaCompletedNCT00052832Phase 21 country
- T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell TransplantTerminatedNCT006517161 country
- Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure DisordersCompletedNCT00856388Not applicable1 country
- Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic CancerCompletedNCT00105001Phase 23 countries
- Total-Body Irradiation, Fludarabine, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic CancerCompletedNCT00044954Phase 21 country
- Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron OverloadTerminatedNCT01159067Phase 21 country
- Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCTTerminatedNCT02627573Phase 21 country
- Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell TransplantationTerminatedNCT01116232Phase 21 country
- Interleukin-2 in Treating Patients With Myelodysplastic SyndromeCompletedNCT00002746Phase 11 country
- Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer, Melanoma, Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Non-Small Cell Lung CancerTerminatedNCT00039091Phase 11 country
- Genetic Susceptibility and Risk of Second Cancers in Patients Who Have Undergone Stem Cell Transplant for CancerTerminatedNCT009490521 country
- Cholecalciferol in Treating Patients With Myelodysplastic SyndromeCompletedNCT00068276Phase 21 country