Legg-Calve-Perthes Disease clinical trials
The registry lists 25 studies for Legg-Calve-Perthes Disease across more than 10 countries. 7 are recruiting or about to start. 15 of them are mainly about Legg-Calve-Perthes Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-17.
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Status
Who runs them
ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. (2) · Zimmer Biomet (2) · Jianming Tan (1) · Second Affiliated Hospital, School of Medicine, Zhejiang University (1) · Istanbul University - Cerrahpasa (1) · Ankara City Hospital Bilkent (1) · Saitama Medical University (1) · The First Affiliated Hospital of Xinxiang Medical College (1)
What is being tested here
Drugs under test in Legg-Calve-Perthes Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Bupivacaine | 1 | 0 | 1 |
| Alendronate | 1 | 0 | 1 |
| Triamcinolone hexacetonide | 0 | 0 | 1 |
| Mesenchymal Stem Cell | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Jul 2027Robotic Arm-assisted THA Vs. Conventional THA in Legg-Calvé-Perthes Disease · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Sep 2027Alendronate for Osteonecrosis in Adults With Sickle Cell Disease · University of California, Davis
Who these studies take
Of the 4 Legg-Calve-Perthes Disease studies recruiting now, 1 (25%) set no upper age limit and 1 (25%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (100%) | 4 (100%) |
| 30 | 4 (100%) | 4 (100%) |
| 40 | 4 (100%) | 4 (100%) |
| 50 | 4 (100%) | 4 (100%) |
| 65 | 4 (100%) | 4 (100%) |
| 75 | 3 (75%) | 3 (75%) |
| 85 | 2 (50%) | 2 (50%) |
Across all 25 studies, recruiting or not: 68% stop at 75 or younger and 48% at 65; 32% take children; 0% are for women only and 0% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 25 of 25. search them.
- Autologous Bone Marrow Aspirate Treatment for Early-Stage OsteonecrosisRecruitingNCT06123481Not applicable1 country
- Alendronate for Osteonecrosis in Adults With Sickle Cell DiseaseRecruitingNCT06016634Phase 21 country
- Screening for Biomarkers of Osteonecrosis of the Femoral HeadRecruitingNCT075456161 country
- Comparison of the Efficacy of Pericapsular Nerve Group Block Alone Versus Pericapsular Nerve Group Block Combined With Superior Cluneal and Superior Gluteal Nerve Blocks in Patients Undergoing Hip SurgeryEnrolling by invitationNCT07255768Not applicable1 country
- Robotic Arm-assisted THA Vs. Conventional THA in Legg-Calvé-Perthes DiseaseEnrolling by invitationNCT07122323Not applicable1 country
- Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes DiseaseEnrolling by invitationNCT0204071415 countries
- PROMIS Evaluation StudyRecruitingNCT057346511 country
- Early Feasibility Study of Cartilage Defect RepairActive, not recruitingNCT06823089Not applicable1 country
- Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH)CompletedNCT075601631 country
- RAB001（LLP2A-Ale） in Healthy SubjectsCompletedNCT07545018Phase 11 country
- A Phase II Trial of RAB001 (LLP2A-Alendronate) for Steroid-Induced Early-Stage Osteonecrosis of the Femoral HeadActive, not recruitingNCT07471880Phase 21 country
- Evaluate E1 Wear, Clinical Performance of E1 Liner in THA in Korean Patient PopulationTerminatedNCT020874491 country
- Perthes Disease in NorwayActive, not recruitingNCT038859601 country
- Kineesiotaping for Patients With LCPDCompletedNCT05840146Not applicable1 country
- Study on Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral HeadTerminatedNCT01529008Phase 3
- Mesenchymal Stem Cells in Osteonecrosis of the Femoral HeadCompletedNCT01605383Phase 1/21 country
- Taperloc Complete Microplasty vs Taperloc Complete Standard: Randomized Controlled Study on Bone Mineral DensityCompletedNCT02087436Not applicable1 country
- The Effect of Perthes' Disease on Hip CartilageCompletedNCT009584641 country
- PHASE II CLINICAL TRIAL Prospective, Open, Nonrandomized Treatment of Osteonecrosis of the Femoral Head by the Administration of Autologous Mesenchymal Stem CellsCompletedNCT01700920Phase 21 country
- A Randomised Multi-centre Study to Compare the Long-term Performance of the Future Hip to 3 Other Implants in Primary Total Hip ReplacementTerminatedNCT00208468Phase 33 countries
- WOMAC Hip Score in Children and Adolescents With Perthes DiseaseStatus unknownNCT027954941 country
- The Long Term Outcome of Varus Derotational Osteotomy for Legg-Calvé-Perthes' DiseaseCompletedNCT026762711 country
- Intraarticular Corticosteroid Therapy in Perthes Disease.TerminatedNCT01026909Not applicable1 country
- Mesenchymal Stem Cell for Osteonecrosis of the Femoral HeadStatus unknownNCT00813267Early Phase 11 country
- Vertebral Fracture and Osteonecrosis Associated With High-dose GlucocorticoidCompletedNCT00679978