Intracranial Aneurysm clinical trials
The registry lists 418 studies for Intracranial Aneurysm across more than 10 countries. 119 are recruiting or about to start. 355 of them are mainly about Intracranial Aneurysm (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Status
Who runs them
Microvention-Terumo, Inc. (21) · Beijing Tiantan Hospital (20) · Medtronic Neurovascular Clinical Affairs (15) · Stryker Neurovascular (14) · Centre hospitalier de l'Université de Montréal (CHUM) (10) · MicroPort NeuroTech Co., Ltd. (8) · Phenox GmbH (8) · Cerus Endovascular, Inc. (7)
What is being tested here
Drugs under test in Intracranial Aneurysm studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Aspirin | 1 | 1 | 3 |
| Clopidogrel | 1 | 0 | 3 |
| Heparin | 1 | 0 | 3 |
| Prasugrel | 1 | 0 | 2 |
| Ticagrelor | 1 | 1 | 2 |
| Atorvastatin | 1 | 0 | 2 |
| Methylprednisolone | 1 | 0 | 1 |
| Nicardipine | 1 | 0 | 1 |
| Nebivolol | 1 | 0 | 1 |
| Ropivacaine | 1 | 0 | 1 |
Drug classes tested here P2Y12 inhibitors 2 open · Beta blockers 1 open · Statins 1 open · Calcium channel blockers 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Mar 2027Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain Aneurysms · Phase 3 · University of Calgary
- Nov 2026Multimodal Approach Feasability Study for Untreated and Unruptured Intracranial Aneurysms · Resolve Stroke
- Nov 2026NIRS and BIS Monitoring During Cerebral Aneurysm Coiling · Dokuz Eylul University
- Nov 2026Patients with Unruptured IntraCranial ANeurysms: Evaluation of the Benefits of Allied Health FollOw-uP in a RandomizEd Controlled Trial · Nantes University Hospital
- Nov 2026General Anesthesia vs Local Anesthesia for Endovascular Treatment in Patients With Unruptured Intracranial Aneurysm Using Flow Diverter · Ming Lv
- Dec 2026LUMENS-1 EU EFS CIP · LuSeed Vascular LTD.
- Dec 2026Post-Market Product Surveillance of Intracranial ANeurysms Treated With Commercial ReGistered ACANDIS Devices in FrancE · Acandis GmbH
- Dec 2026NEUROvascular NAVigation With Remotely Controlled Deflectable Guidewire, Study I (NeuroNAV Study I) · Artiria Medical
- Dec 2026Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry · HCA Healthcare Research Institute
- Dec 2026Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm · Jacobs institute
Who these studies take
Of the 82 Intracranial Aneurysm studies recruiting now, 49 (60%) set no upper age limit and 14 (17%) stop at 75 or younger. 15 (18%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 6 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 15 (18%) | 15 (18%) |
| 18 | 75 (91%) | 75 (91%) |
| 30 | 82 (100%) | 82 (100%) |
| 40 | 82 (100%) | 82 (100%) |
| 50 | 82 (100%) | 82 (100%) |
| 65 | 80 (98%) | 80 (98%) |
| 75 | 80 (98%) | 80 (98%) |
| 85 | 52 (63%) | 52 (63%) |
Across all 418 studies, recruiting or not: 19% stop at 75 or younger and 3% at 65; 14% take children; <1% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Intracranial Aneurysm studies take
Of 104 interventional studies with no phase under Intracranial Aneurysm, half reached primary completion within 39 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 39 mo22–69 · 104 studies | 28 mo19–49 · 48 studies | 59 mo30–134 · 56 studies |
| Observational | 46 mo36–145 · 104 studies | — | 54 mo26–145 · 67 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting4
- Complex Aneurysm Registry - Real-World Evidence Data Collection for Intracranial Aneurysm Treatment DevicesNov 10, 2026NCT06215105
- Evaluation of Intestinal Microbiota Implication in Ruptured Intracranial AneurysmNov 2, 2026NCT05914636
- NIRS and BIS Monitoring During Cerebral Aneurysm CoilingOct 21, 2026NCT07438275
- Multimodal Approach Feasability Study for Untreated and Unruptured Intracranial AneurysmsOct 13, 2026NCT07864389
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 418. Browse all 418 → or search them.
- Complex Aneurysm Registry - Real-World Evidence Data Collection for Intracranial Aneurysm Treatment DevicesRecruitingNCT062151051 country
- A Study of Choydar Flow-Directed Mesh Stent in the Treatment of Unruptured Intracranial AneurysmsRecruitingNCT072283121 country
- Effect of Bilateral Greater Occipital Nerve Block on Headache After Intracranial Aneurysm CoilingNot yet recruitingNCT07910864Not applicable1 country
- Evaluation of Intestinal Microbiota Implication in Ruptured Intracranial AneurysmRecruitingNCT059146361 country
- Efficacy and Safety of Methylprednisolone After Flow-Diverter Stent Implantation in Unruptured Intracranial AneurysmsNot yet recruitingNCT07353749Phase 41 country
- Prospective Observational Cohort Study for Predicting Unruptured Intracranial Aneurysm Rupture Risk Using Blood Pressure Variability and 3D Structural EvolutionRecruitingNCT078935741 country
- NV PSR INSPIRE-A Pipeline™ Vantage Post Approval StudyRecruitingNCT066048841 country
- Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)RecruitingNCT06872684Not applicable1 country
- NIRS and BIS Monitoring During Cerebral Aneurysm CoilingRecruitingNCT074382751 country
- Product Surveillance RegistryRecruitingNCT0152427641 countries
- Multimodal Approach Feasability Study for Untreated and Unruptured Intracranial AneurysmsRecruitingNCT07864389Not applicable1 country
- The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial AneurysmsRecruitingNCT07143019Not applicable1 country
- The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).RecruitingNCT02998229Not applicable1 country
- Hyperoxemia and Oxygen Reserve Index During Neurointerventional AnesthesiaNot yet recruitingNCT078599821 country
- Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)RecruitingNCT07225075Not applicable2 countries
- Lumbar Drain With Intrathecal Nicardipine in Aneurysmal Subarachnoid HemorrhageNot yet recruitingNCT07246629Phase 41 country
- Unruptured Cerebral Aneurysm: Prediction of EvolutionRecruitingNCT045788083 countries
- International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)RecruitingNCT061747272 countries
- Post-Market Active Surveillance and Health Economic Evaluation of Cerebrovascular Diagnostic and Therapeutic DevicesNot yet recruitingNCT07828379
- A Multicenter Prospective Study of New Flow Diverter Stent on the Treatment of Intracranial Aneurysms in ChinaRecruitingNCT07821957Not applicable1 country
- Neurovascular Product Surveillance RegistryRecruitingNCT0298812824 countries
- Surveillance Versus Treatment of Unruptured Intracranial Aneurysms of Fortuitous DiscoveryNot yet recruitingNCT07817511Not applicable1 country
- Multimodal Physiologic State Intelligence StudyEnrolling by invitationNCT078141181 country
- Multimodal Biocollection Linked to the French Register of Intracranial AneurysmsRecruitingNCT06689410Not applicable1 country
- Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain AneurysmsRecruitingNCT04192955Phase 32 countries
- General Anesthesia vs Local Anesthesia for Endovascular Treatment in Patients With Unruptured Intracranial Aneurysm Using Flow DiverterRecruitingNCT06416657Not applicable1 country
- The TERUMO FRED X EARLY FEASIBILITY STUDY (FAST) STUDY.Not yet recruitingNCT07761598Not applicable1 country
- MRI Analysis in the Growth of Cerebral AneurysmsRecruitingNCT06705452Not applicable1 country
- Intelligent Microcatheter Shaping for Intracranial Aneurysm Coil EmbolizationNot yet recruitingNCT077494041 country
- PMCF Registry to Describe the Safety and Performance of p64, p48 MW and p64 MW in FranceRecruitingNCT077485721 country
- Evaluating a Wireless NIRS Device in the Neonatal Intensive Care UnitRecruitingNCT07732244Not applicable1 country
- Flow Diverter Versus Conventional Endovascular Treatment for Unruptured Wide-Neck Bifurcation Aneurysms (FD-BWA Trial)RecruitingNCT07707076Not applicable1 country
- Surface-Modified Flow Diverter for Intracranial Aneurysms: Assessment of Ischemic and Clinical OutcomesRecruitingNCT07674004Not applicable1 country
- Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil EmbolizationNot yet recruitingNCT07660861Not applicable1 country
- Real-World Study of Woven EndoBridge for Intracranial Aneurysm TreatmentRecruitingNCT076206261 country
- Interest of a Simulated Procedure Performed on a Printed Model in the Endovascular Treatment of Carotid-sylvian AneurysmsNot yet recruitingNCT05419661Not applicable1 country
- Prospective Study of High-penetration Super-resolution Transcranial Ultrasound for Early Identification of Postoperative Intracranial Metallic Targets After Aneurysm ClippingNot yet recruitingNCT07583225
- Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid HemorrhageRecruitingNCT05103566Not applicable1 country
- Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic MappingRecruitingNCT065885431 country
- Assessment of the Clinical and Economic Impact of Sim&Size, a Simulation Software for Implantable Devices Used in the Treatment of Intracranial Aneurysms: A Prospective Multicenter Study.RecruitingNCT07433075Not applicable1 country
- Clinical, Organizational, and Care Impact of the GetReady Digital Platform as a Clinical Decision Support Tool in the Follow-up of Patients With Cerebral AneurysmNot yet recruitingNCT07569562Not applicable
- NOn-inVAsive Blood Pressure Monitoring in Intracranial Aneurysm EmbolizationRecruitingNCT07246148Not applicable1 country
- Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)RecruitingNCT06693011Not applicable1 country
- This Three-year Observational Study Involves Patients of All Ages Undergoing Endovascular Treatment for Various Cerebral or Spinal Vascular Conditions. It Aims to Assess Pre- and Post-operative Clinical Conditions, Report Complications, and Identify Preoperative Indicators of Treatment Outcomes. PatRecruitingNCT068057211 country
- INdobufen Versus asPirin in Endovascular Unruptured Intracranial Aneurysms Treatment (INPUT)RecruitingNCT07089862Not applicable1 country
- Targeting Real World Usage In Stroke TreatmentRecruitingNCT074749355 countries
- Middle Cerebral Artery Aneurysm TrialRecruitingNCT05161377Not applicable1 country
- PC400 Coils for Treatment of Intracranial AneurysmsNot yet recruitingNCT074648471 country
- Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter ImplantationRecruitingNCT06308952Phase 41 country
- Investigation of Protein Heterogeneity in Extracellular Vesicles Derived From Different Human Blood Circulatory RegionsRecruitingNCT074399651 country