Ichthyosis clinical trials
The registry lists 33 studies for Ichthyosis across 8 countries. 11 are recruiting or about to start. 22 of them are mainly about Ichthyosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 3 narrower conditions too, such as Ichthyosis Bullosa of Siemens: 80 studies, 22 open.
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Who runs them
Northwestern University (6) · University Hospital, Toulouse (4) · University of Nebraska (2) · National Cancer Institute (NCI) (2) · Krystal Biotech, Inc. (2) · Maastricht University Medical Center (2) · LEO Pharma (1) · Cellegy Pharmaceuticals (1)
What is being tested here
Drugs under test in Ichthyosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Gentamicins | 1 | 0 | 1 |
| Dupilumab | 1 | 0 | 1 |
| Deucravacitinib | 0 | 0 | 1 |
| ADX-629 | 0 | 0 | 1 |
| Ustekinumab | 0 | 0 | 1 |
| Secukinumab | 0 | 0 | 1 |
| Monolaurin | 0 | 1 | 1 |
| Imsidolimab | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Mar 2027FARD (RaDiCo Cohort) (RaDiCo-FARD) · Institut National de la Santé Et de la Recherche Médicale, France
- Jun 2027Thera-Clean® Microbubbles System in Patients With Skin Diseases · Northwestern University
- Jun 2027Cholesterol Cream vs Urea Cream for Skin Barrier and Quality of Life in Ichthyosis · Institute of Dermatology, Thailand
Who these studies take
Of the 5 Ichthyosis studies recruiting now, 5 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 5 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (80%) | 4 (80%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 33 studies, recruiting or not: 33% stop at 75 or younger and 24% at 65; 76% take children; 3% are for women only and 0% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 33 of 33. search them.
- Thera-Clean® Microbubbles System in Patients With Skin DiseasesEnrolling by invitationNCT07050810Early Phase 11 country
- Patient Study to Evaluate the Safety and Emollient Performance of Doublebase Once in the Treatment of IchthyosisNot yet recruitingNCT07783165Not applicable
- Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)RecruitingNCT066699491 country
- Cholesterol Cream vs Urea Cream for Skin Barrier and Quality of Life in IchthyosisNot yet recruitingNCT07689435Not applicable1 country
- Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin DisordersRecruitingNCT05649098Early Phase 11 country
- Defining the Skin and Blood Biomarkers of IchthyosisEnrolling by invitationNCT034178561 country
- Evaluate the Evolution of Body and Scalp Skin Discomfort in Patients With Hereditary Ichthyosis After Wraps (EnvelopIchtyose)RecruitingNCT05979506Not applicable1 country
- FARD (RaDiCo Cohort) (RaDiCo-FARD)RecruitingNCT059544161 country
- Reproductive Options in Inherited Skin DiseasesEnrolling by invitationNCT063303241 country
- Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive CounsellingRecruitingNCT063303501 country
- Efficacy of Injectable Gentamicin in Hereditary IchthyosisNot yet recruitingNCT06362447Phase 21 country
- A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory GenodermatosesCompletedNCT06136403Phase 21 country
- Evaluation of Topical ATR12-351 in Adults With Netherton SyndromeCompletedNCT06137157Phase 11 country
- The ASCEND Study: Evaluating TMB-001 in the Treatment of RXLI or ARCI IchthyosisCompletedNCT05295732Phase 35 countries
- ADX-629 Therapy for Sjogren-Larsson SyndromeCompletedNCT05443685Phase 1/21 country
- Ophthalmological Abnormalities in Hereditary Ichthyosis (ICHTYO-KERATO)CompletedNCT03464994Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With IchthyosisTerminatedNCT04697056Phase 21 country
- A Clinical Evaluation of Marula-Derived Ceramide Cream on Skin Barrier Function EnhancementCompletedNCT07066150Not applicable1 country
- An Open-Label and Long-Term Extension Study to Evaluate the Efficacy and Safety of Ustekinumab in the Treatment of Patients With IchthyosesCompletedNCT04549792Early Phase 11 country
- Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types.CompletedNCT05932732Phase 41 country
- Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical MarkersCompletedNCT019719571 country
- Therapeutic Education Using an Internet Application in Hereditary IchthyosisCompletedNCT03641261Not applicable1 country
- Topical KB105 for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)Status unknownNCT05735158Phase 21 country
- A Study of Topical NS2 Cream to Treat Ichthyosis in Sjögren-Larsson Syndrome (SLS)CompletedNCT02402309Phase 21 country
- National Registry for Ichthyosis and Related DisordersCompletedNCT000746851 country
- Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)Status unknownNCT04047732Phase 1/21 country
- The Efficacy and Safety of Secukinumab in Patients With IchthyosesCompletedNCT03041038Phase 21 country
- Study Determining Safety and Efficacy of Avena Sativa (Oat) Skincare Products for Treating Skin Dryness and Itching in Cancer PatientsCompletedNCT03796052Not applicable1 country
- Asthma and Atopic Dermatitis Validation of PROMIS Pediatric InstrumentsCompletedNCT03051347Not applicable1 country
- A Multi-center, Prospective Evaluation of Infants and Children With Congenital IchthyosisTerminatedNCT026558611 country
- Phase III Study of Monolaurin Cream Therapy for Patients With Congenital IchthyosisCompletedNCT00004690Phase 3
- Study of Scaling Disorders and Other Inherited Skin DiseasesCompletedNCT000012921 country
- The Evaluation of Oral Acitretin in the Treatment of Psoriasis, Cutaneous Disorders of Keratinization, Multiple Basal Cell Carcinomas and Other Retinoid Responsive DiseasesCompletedNCT000056601 country