Hypoparathyroidism clinical trials
The registry lists 119 studies for Hypoparathyroidism across more than 10 countries. 29 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 61
- Recruiting
- 25
- Status unknown
- 14
- Active, not recruiting
- 5
- Terminated
- 5
- Not yet recruiting
- 4
Phase
- Phase 3
- 20
- Phase 2
- 19
- Phase 1
- 9
- Phase 4
- 8
- Early Phase 1
- 3
Where
- United States
- 39
- Denmark
- 20
- France
- 16
- Italy
- 15
- Canada
- 13
- Germany
- 8
Who runs them
Shire (10) · University of Aarhus (5) · Ascendis Pharma A/S (4) · Aristotle University Of Thessaloniki (4) · Amorphical Ltd. (3) · Entera Bio Ltd. (3) · Calcilytix Therapeutics, Inc., a BridgeBio company (3) · Peking Union Medical College Hospital (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 119 — search for more.
- A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With HypoparathyroidismRecruitingNCT07699471Phase 31 country
- Postoperative Hypocalcemia After ThyroidectomyRecruitingNCT074280571 country
- Efficacy, Safety, and Tolerability of Encaleret in Participants With Chronic HypoparathyroidismRecruitingNCT07805356Phase 32 countries
- A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With HypoparathyroidismRecruitingNCT07081997Phase 31 country
- A Study to Assess the Amount of Palopegteriparatide in Breast Milk of Lactating Females Requiring YORVIPATH® (Palopegteriparatide)RecruitingNCT072646341 country
- A Study to Test the Effects and Safety of Palopegteriparatide in Adolescents With Long-term HypoparathyroidismRecruitingNCT07706764Phase 32 countries
- NIRAF-Guided Parathyroid Identification During ThyroidectomyNot yet recruitingNCT07617584Not applicable1 country
- A Cohort Study on the Safety and Efficacy of XH-02 in Treating HypoparathyroidismRecruitingNCT07540286Phase 21 country
- Risk Factors for Hypoparathyroidism Following ThyroidectomyRecruitingNCT075825621 country
- Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)RecruitingNCT070835571 country
- Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total ThyroidectomyRecruitingNCT04785443Phase 31 country
- A Global Pregnancy Registry to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to YORVIPATH® (Palopegteriparatide) During Pregnancy and BreastfeedingRecruitingNCT073454941 country
- Parathyroid Allotransplant for Treatment of HypoparathyroidismRecruitingNCT06961071Phase 1/21 country
- Comparing PTeye-assisted Versus Conventional Total ThyroidectomyRecruitingNCT07416149Not applicable1 country
- Hypoparathyroidism Natural History StudyRecruitingNCT057938531 country
- Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent HypoparathyroidismRecruitingNCT06222606Not applicable1 country
- Translation and Validation of the Hypoparathyroidism Patient Experience Scales (HPES) Questionnaire in GreekNot yet recruitingNCT07160348
- Treatment With Indapamide in Patients With Post-Surgical HypoparathyroidismRecruitingNCT07034677Phase 41 country
- A Phase 2 Trial Investigating the Safety, Tolerability and Efficacy of EXT608 in Adults With HypoparathyroidismRecruitingNCT06988670Phase 21 country
- Psychological Problems in Post Thyroidectomy PatientsNot yet recruitingNCT06929104
- Tunisian Clinical Registry on Hypoparathyroidism and Pseudo-hypoparathyroidismNot yet recruitingNCT064450361 country
- Intraoperative Monitoring to Predict Postoperative Complications After ThyroidectomyRecruitingNCT033093841 country
- Establishment of a Registry of Patients with Parathyroid DiseaseRecruitingNCT067979341 country
- Institution of an Italian Multicenter Database of Patients Affected by Hypoparathyroidism or PseudohypoparathyroidismRecruitingNCT066458991 country
- Survey on Epidemiology of Hypoparathyroidism in FranceRecruitingNCT028389271 country
- Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy HypoparathyroidismRecruitingNCT03249012Not applicable1 country
- Parathyroid Allotransplant for Severe Refractory HypoparathyroidismRecruitingNCT06499246Not applicable1 country
- Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After ThyroidectomyRecruitingNCT05117853Phase 31 country
- Registry for Hypoparathyroidism WuerzburgRecruitingNCT055855931 country
- Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult HypoparathyroidismSuspendedNCT07530705Phase 1/21 country
- Efficacy and Safety of XH02 for the Treatment of HypoparathyroidismSuspendedNCT07197450Early Phase 11 country
- Parathyroid Allotransplantation in Medically Refractory HypoparathyroidismWithdrawnNCT05114980Not applicable1 country
- Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in AdultsActive, not recruitingNCT06547151Phase 21 country
- Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1Active, not recruitingNCT05680818Phase 310 countries
- A Registry for Participants With Chronic HypoparathyroidismCompletedNCT0192244011 countries
- A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With HypoparathyroidismCompletedNCT04701203Phase 37 countries
- Postoperative Dose of Parathyroid Hormone as a Marker for the Occurrence of Hypoparathyroidism After Total ThyroidectomyCompletedNCT029245321 country
- A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With HypoparathyroidismCompletedNCT04009291Phase 26 countries
- ADH1 and ADH2 Disease Monitoring Study (DMS)Active, not recruitingNCT0522728713 countries
- Safety, Pharmacokinetics and Efficacy of MBX 2109 in Patients With HypoparathyroidismCompletedNCT06465108Phase 23 countries
- PTH-independent Effects of EncaleretCompletedNCT05735015Phase 21 country
- Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic HypoparathyroidismCompletedNCT00743782Phase 21 country
- Assess Safety and Compare PK of New Oral hPTH(1-34) Tablet Formulations vs. EBP05 Tablets and Subcutaneous ForteoCompletedNCT05965167Phase 11 country
- Intraoperative Methylene Blue Spray for the Identification and Preservation of Vital Structures in ThyroidectomyCompletedNCT07395388Not applicable1 country
- Palopegteriparatide in Chronic HypoparathyroidismCompletedNCT072998381 country
- A Survey to Assess Participants' and Physicians' Knowledge, Attitudes and Behavior When Using NATPARACompletedNCT055566291 country
- PaTHway CHINA TRIAL: A Trial to Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With HypoparathyroidismCompletedNCT05387070Phase 31 country
- Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With HypoparathyroidismActive, not recruitingNCT06531941Phase 23 countries
- Evaluation of the Safety and Efficacy of Eneboparatide (AZP-3601) in Patients With Chronic HypoparathyroidismActive, not recruitingNCT05778071Phase 313 countries
- Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total ThyroidectomyCompletedNCT05022667Not applicable1 country