Hyperlipoproteinemia Type II: all 249 studies

Page 3 of 3. Open to participants first (52), then studies with results posted, then the rest; newest registration first within each.

• Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering TherapyWithdrawnNCT02765841Phase 3
• Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, GermanyCompletedNCT02750527
• Postprandial Response After Intake of Meals With Different Fatty Acid CompositionCompletedNCT02729857Not applicable
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial HypercholesterolemiaCompletedNCT02709850Phase 1
• MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)Status unknownNCT02517944
• Atherosclerosis in Familial HypercholesterolemiaStatus unknownNCT02489253
• Study to Evaluate the Effects of MBX-8025 in Patients With HoFHCompletedNCT02472535Phase 2
• Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial HypercholesterolemiaCompletedNCT02462655Not applicable
• Effects of Lomitapide on Carotid and Aortic AtherosclerosisWithdrawnNCT02399852
• Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial HypercholesterolemiaCompletedNCT02286596
• Relationships Between Plasma PCSK9 Levels, LDL-cholesterol Concentrations and Lipoprotein (a) Levels in Familial HypercholesterolemiaCompletedNCT02225340
• Efficacy of a New Symbiotic Formulation in Children With Familial HypercholesterolemiaCompletedNCT02048410Phase 1/2
• French Observatory of Familial Hypercholesterolemia in CardiologyTerminatedNCT02013713
• Effect of Weight Loss on Cholesterol Metabolism in Hereditary Hypercholesterolemias and Overweight or Obesity.CompletedNCT01995149Not applicable
• Comparison of the Efficacy and Safety of AtorVastatin mOnotherapy vs. Combination Atorvastatin/Fenofibric AcidStatus unknownNCT01974297Not applicable
• Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)TerminatedNCT01841684Phase 3
• A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)CompletedNCT01824238Phase 3
• Effect of Omega-3 Fatty Acid on Endothelial FunctionCompletedNCT01813006Phase 3
• Cardiovascular Disease in FH HeterozygousStatus unknownNCT01783405
• Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein FilterCompletedNCT01753232
• Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish OilsStatus unknownNCT01577056Not applicable
• Exploratory Study of Plaque RegressionCompletedNCT01515241Phase 2
• Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) SubjectsCompletedNCT01412034Phase 2
• Efficacy and Safety Study of Eprotirome in HeFH Patients Who Are on Optimal Standard of CareTerminatedNCT01410383Phase 3
• Effects of Low-density Lipoprotein (LDL) Apheresis on Inflammatory and Lipid MarkersCompletedNCT01138371
• Soy Food Intervention TrialStatus unknownNCT00924339Not applicable
• Effect of Rapeseed Oil and Sunflower OilStatus unknownNCT00924274Not applicable
• Effect of APL180 on Endothelial Function in Familial Hypercholesterolemia PatientsWithdrawnNCT00751608Phase 2
• A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)CompletedNCT00705211
• A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)CompletedNCT00704444
• Efficacy and Safety Study of JTT-705 in Combination With Pravastatin 40 mg in Patients With Type II HyperlipidemiaCompletedNCT00688896Phase 2
• Efficacy and Safety of JTT-705 300, 600 And 900mg in Comparison With Placebo in Patients With Type II HyperlipidaemiaCompletedNCT00686010Phase 2
• A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing MedicationCompletedNCT00655265Phase 4
• Bone Marrow Stem Cells as a Source of Allogenic Hepatocyte Transplantation in Homozygous Familial HypercholesterolemiaCompletedNCT00515307Phase 1
• Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus EzetimibeStatus unknownNCT00475826Not applicable
• Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering TherapyCompletedNCT00281008Phase 2
• Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering TherapyCompletedNCT00280995Phase 2
• Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial HypercholesterolemiaTerminatedNCT00263081Phase 3
• Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial HypercholesterolemiaCompletedNCT00171236Phase 3
• Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.TerminatedNCT00151788Phase 2/3
• Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.CompletedNCT00136981Phase 3
• Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol DisorderCompletedNCT00134511Phase 3
• Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial HypercholerolemiaCompletedNCT00134485Phase 3
• Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)TerminatedNCT00092833Phase 3
• Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering TherapyTerminatedNCT00079859Phase 2
• Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering TherapyTerminatedNCT00079846Phase 2
• Hyperapo B and Coronary Heart DiseaseCompletedNCT00005168
• Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial HypercholesterolemiaCompletedNCT00004809Phase 1
• NHLBI Type II Coronary Intervention StudyCompletedNCT00000594Phase 3

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