Hypercholesterolemia: all 1,267 studies

Page 8 of 13. Open to participants first (105), then studies with results posted, then the rest; newest registration first within each.

• Nutraceutical in Cardiovascular Primary PreventionCompletedNCT03216811Phase 2
• Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)WithdrawnNCT03198897
• A Defined, Plant-based, 4-week Dietary Intervention Reduces Lp(a) and Other Atherogenic ParticlesCompletedNCT03172611Not applicable
• A Registration Study for Familial Hypercholesterolemia in TaiwanStatus unknownNCT03152656
• HDL Acute Lipid Optimization in Homozygous Familial HypercholesterolemiaStatus unknownNCT03135184Not applicable
• Effects of a 4-week Raw, Plant-based Diet on Anthropometric and Cardiovascular Risk FactorsCompletedNCT03134235Not applicable
• Effects of Atorvastatin in Graves' Orbitopathy (GO)CompletedNCT03110848Phase 2
• Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication RegistryCompletedNCT03110432
• Familial Hypercholesterolemia in Turkey (A-HIT2)CompletedNCT03110250
• Cardiovascular Health Promotion Among African-Americans by FAITH!CompletedNCT03084822Not applicable
• Effect of Red Yeast Rice, Phytosterols and L-tyrosol on Lipid Profile and Endothelial FunctionCompletedNCT03065491Not applicable
• Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial HypercholesterolemiaCompletedNCT03018678
• The Effect of Olive Leaf Extract Administration on Cardiovascular HealthCompletedNCT02990637Not applicable
• Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and HypertriglyceridemiaCompletedNCT02989753Phase 1/2
• A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous (SC) Administered Alirocumab in Healthy Chinese SubjectsCompletedNCT02979015Phase 1
• Lp(a) and Aortic Valve CalcificationCompletedNCT02976818
• Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow ReserveCompletedNCT02969070Not applicable
• Evolocumab Pregnancy Exposure RegistryTerminatedNCT02957604
• Clinical Trial to Evaluate the Efficacy and Safety of DP-R212WithdrawnNCT02955368Phase 3
• Latinos Understanding the Need for AdherenceCompletedNCT02955238Not applicable
• Evaluate the Pharmacokinetics and Safety of HCP1306 and Co-administration of HGP0816, HGP1404 in Healthy Male VolunteersCompletedNCT02941848Phase 1
• Safety and Tolerability of VK2809 in Patients With Primary Hypercholesterolemia and Non-Alcoholic Fatty Liver DiseaseCompletedNCT02927184Phase 2
• Nattokinase Supplementation and Hemostatic FactorsCompletedNCT02913170Phase 4
• Study to Evaluate the Safety of Repatha® in PregnancyTerminatedNCT02906124
• Familial Hypercholesterolemia Amongst Patients With Acute Coronary SyndromeStatus unknownNCT02870660
• Developing and Implementing Familial Hypercholesterolemia RegistryStatus unknownNCT02865694
• Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their ParentsCompletedNCT02857543Not applicable
• Pediatric Preventative Health Screenings - Obesity and Family-Centered OutcomesCompletedNCT02850224Not applicable
• A Study to Evaluate the Effects of Dietary Fiber on Blood Lipids in Men and WomenCompletedNCT02835872Not applicable
• Proteus Discover in Subjects With Uncontrolled Hypertension and Type 2 DiabetesCompletedNCT02827630Not applicable
• Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary InterventionTerminatedNCT02818283Not applicable
• Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in JapanCompletedNCT02808403
• Detection of Familial Hypercholesterolaemia in Cardiovascular Disease RegistryCompletedNCT02778646
• Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and EzetimibeCompletedNCT02772640Phase 4
• Chart Review of Repatha® in Subjects With HyperlipidaemiaCompletedNCT02770131
• Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering TherapyWithdrawnNCT02765841Phase 3
• Genetic Basis for Prediction of Non-responders to Dietary Plant Sterol InterventionTerminatedNCT02765516Not applicable
• Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, GermanyCompletedNCT02750527
• A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study)CompletedNCT02749994Phase 3
• Efficacy of a LRC™ (L. Reuteri NCIMB 30242) Capsule on Managing Cholesterol in AdultsCompletedNCT02734706Not applicable
• Postprandial Response After Intake of Meals With Different Fatty Acid CompositionCompletedNCT02729857Not applicable
• The Effects of a Spread With Added Plant Sterols and Omega-3 Fatty Acids on Blood LipidsCompletedNCT02728583Not applicable
• Graves' Orbitopathy and HypercholesterolemiaCompletedNCT02721992
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial HypercholesterolemiaCompletedNCT02709850Phase 1
• Impact of Ketogenic Diets on Cardiovascular Health in Adults With EpilepsyActive, not recruitingNCT02694094
• Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS)CompletedNCT02693782Not applicable
• Efficacy of a Red Yeast Rice Based Nutraceutical Plus Probiotic in Patients With Moderate HypercholesterolemiaCompletedNCT02689934Not applicable
• Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human HyaluronidaseTerminatedNCT02667223Phase 1
• Measuring the Impact of Dietary Supplementation With a New Baking Product on Gut Microbiota and Cholesterol MetabolismCompletedNCT02664428Not applicable
• EFFECTS OF CARDICHOL, AN HERBAL DIETARY SUPPLEMENT, IN MODERATE HYPERCHOLESTEROLEMIAStatus unknownNCT02657759Not applicable
• Single Dose Study of PF-06815345 in Healthy SubjectsTerminatedNCT02654899Phase 1
• Lipid-lowering Effect of Plant Stanol Ester Yoghurt DrinksCompletedNCT02628990Not applicable
• The Cholesterol Lowering Effects of StrawberryCompletedNCT02612090Not applicable
• Effects of α-linolenic Acid Supplementation on Hemostasis in Nondiabetic and Hypercholesterolemic SubjectsCompletedNCT02609295Phase 3
• A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With HypercholesterolemiaCompletedNCT02608697Phase 2
• A Survey on the Under-treatment of hypercholeSterolemia (EPHESUS Trial)Status unknownNCT02608645
• Lipid-lowering Effect of Phytosterols, Red Yeast Rice and Their CombinationCompletedNCT02603276Not applicable
• Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With AtorvastatinCompletedNCT02591836Phase 2
• Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy VolunteersCompletedNCT02587416Phase 1
• Effect of Gemcabene on the Pharmacokinetics of Simvastatin in Healthy VolunteersCompletedNCT02587390Phase 1
• Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy VolunteersCompletedNCT02587364Phase 1
• Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated TriglyceridesCompletedNCT02585869Phase 2
• Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary StudyCompletedNCT02579655Not applicable
• Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin TherapyCompletedNCT02571257Phase 2
• Effect of Statin Treatment on Urinary AQP2 (uAQP2/01)CompletedNCT02523001
• High Potency Statins and Acute Kidney InjuryCompletedNCT02518516
• MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)Status unknownNCT02517944
• Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy SubjectsCompletedNCT02508896Phase 1
• Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative PatientsTerminatedNCT02499185Phase 4
• Retinoic Acid Supplementation and Subjects With HypercholesterolemiaCompletedNCT02497833Early Phase 1
• Atherosclerosis in Familial HypercholesterolemiaStatus unknownNCT02489253
• The Combined Portfolio Diet and Exercise StudyCompletedNCT02481466Not applicable
• The Effect of Shuhua Milk Fortified With Plant Sterol Esters on Serum Cholesterol in HumanCompletedNCT02475018Not applicable
• Study to Evaluate the Effects of MBX-8025 in Patients With HoFHCompletedNCT02472535Phase 2
• Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial HypercholesterolemiaCompletedNCT02462655Not applicable
• Comparison of the Efficacy of Plant Sterol-Enriched Soymilk Versus Plain Soymilk in Volunteers With High LDL-CholesterolCompletedNCT02459314Not applicable
• Efficacy/Safety of DP-R207 Tablet Versus CRESTOR Tablet in Patients With Primary HypercholesterolemiaCompletedNCT02445352Phase 3
• Nutraceutical Combination in Patients With Low-grade Systemic InflammationCompletedNCT02422927Phase 4
• Effects of Dietary Antioxidants to Prevent Cardiovascular DiseaseCompletedNCT02409537Phase 2
• Effects of Lomitapide on Carotid and Aortic AtherosclerosisWithdrawnNCT02399852
• Atorvastatin Study in Cardiovascular Disease RiskCompletedNCT02392416
• Phase 3 Study to Evaluate the Efficacy and Safety of the DW0929 in Patients With Primary HypercholesterolemiaCompletedNCT02390375Phase 3
• A 2-Part, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CAT-2054 in Healthy SubjectsCompletedNCT02374047Phase 1
• A Clinical Trial for Evaluation of Adequate Dose and Safety of DW-3102 in Hypercholesterolemia PatientsStatus unknownNCT02368613Phase 2
• Validating the "Foods for Health" Portfolio of Functional Food ProductsCompletedNCT02341924Not applicable
• Patient and Provider Assessment of Lipid Management RegistryCompletedNCT02341664
• Serum Cholesterol Reduction Efficacy of Biscuit With Plant Stanol EsterCompletedNCT02331043Not applicable
• Physical Exercise Prescription With PEdometeR in General Practice for Patients With Cardiovascular Risk Factors - PEPPERCompletedNCT02317003Not applicable
• Cholesterol-lowering Effects of Plant Stanol EsterCompletedNCT02316808Not applicable
• Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With HypercholesterolaemiaStatus unknownNCT02314663Not applicable
• A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)CompletedNCT02314442Phase 1
• The Effect of Plant Sterols on the Blood Lipid Profile of Subjects With and at High Risk of Type 2 Diabetes MellitusCompletedNCT02288585Not applicable
• Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial HypercholesterolemiaCompletedNCT02286596
• The Efficacy and Safety of a Combination Therapy of Rosuvastatin and Ezetimibe Versus Monotherapy of Rosuvastatin in Hypercholesterolemia PatientsStatus unknownNCT02251847Phase 3
• CEntralized Pan-Russian Survey of tHE Undertreatment of hypercholeSterolemia II (CEPHEUS II)CompletedNCT02230241
• Relationships Between Plasma PCSK9 Levels, LDL-cholesterol Concentrations and Lipoprotein (a) Levels in Familial HypercholesterolemiaCompletedNCT02225340
• Lipid-lowering Effect of a Plant Stanol Ester Supplement ProductCompletedNCT02221297Not applicable
• Effect of L. Reuteri NCIMB 30242 on Plasma Bile Acid ProfileCompletedNCT02216825Phase 2
• Efficacy/Safety of HCP1306 Tablet Versus HGP0816 Tablet in Patients With Primary HypercholesterolemiaCompletedNCT02205606Phase 3
• A Trial to Evaluate the Efficacy of AB-Life Probiotic Product on LDL-Cholesterol Reduction in Moderate HypercholesterolemiaCompletedNCT02198703Not applicable

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