Hypercholesterolemia: all 1,267 studies

Page 4 of 13. Open to participants first (105), then studies with results posted, then the rest; newest registration first within each.

• Bioequivalence Study Comparing A New 80 Mg Atorvastatin Tablet To A 80 Mg Atorvastatin Commercial TabletCompletedNCT00917644Phase 4Results posted
• Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial TabletCompletedNCT00917579Phase 4Results posted
• Low-Density Lipoprotein (LDL) Apheresis Using H.E.L.P. TherapyCompletedNCT00916643Phase 4Results posted
• Post-marketing Surveillance of the Safety, Tolerability and Efficacy of Vytorin (Ezetimibe + Simvastatin) Tablet Among Filipino Patients (Study P05647)CompletedNCT00909389Results posted
• Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol TargetsCompletedNCT00908011Not applicableResults posted
• Alternative Options to Minimize Niacin-Induced FlushingCompletedNCT00895193Not applicableResults posted
• Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With HypercholesterolemiaCompletedNCT00889226Phase 4Results posted
• Effect of Diabetes Mellitus on Cholesterol MetabolismCompletedNCT00879710Not applicableResults posted
• Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)CompletedNCT00867165Phase 3Results posted
• Phytosterols, Ezetimibe, and Cholesterol MetabolismCompletedNCT00863265Early Phase 1Results posted
• Bioavailability Study for New Atorvastatin FormulationCompletedNCT00844376Phase 4Results posted
• Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated HypertriglyceridemiaCompletedNCT00833976Phase 4Results posted
• Atorvastatin Three Year Pediatric StudyCompletedNCT00827606Phase 3Results posted
• Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and TriglyceridesCompletedNCT00812955Phase 3Results posted
• Effects of Ezetimibe on the Absorption of Oxidized CholesterolCompletedNCT00794677Phase 4Results posted
• Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on ApheresisCompletedNCT00794664Phase 3Results posted
• A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia (MK0653-139)CompletedNCT00783263Phase 3Results posted
• Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)CompletedNCT00782184Phase 3Results posted
• Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic PatientsCompletedNCT00770146Phase 3Results posted
• A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED)CompletedNCT00769132Phase 1Results posted
• Evaluation of LDL Cholesterol in Patients Switched From 10 to 5 Milligrams of Zetia (Ezetimibe)CompletedNCT00762229Not applicableResults posted
• Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) CholesterolCompletedNCT00762164Phase 4Results posted
• Effects of Prescription Omega-3 on LDL-C in Primary HypercholesterolemiaCompletedNCT00746811Phase 4Results posted
• 8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial HypercholesterolemiaCompletedNCT00739999Phase 1Results posted
• A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)CompletedNCT00730236Phase 3Results posted
• Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)CompletedNCT00730132Results posted
• Retrospective Evaluation of the Percentage of Subjects Who Have Reached Their LDL-C Objectives After Treatment With INEGY (Study P05103)(COMPLETED)CompletedNCT00724477Results posted
• Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant SubjectsCompletedNCT00707746Phase 2Results posted
• Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery DiseaseCompletedNCT00706849Phase 3Results posted
• Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)CompletedNCT00705081Results posted
• Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)CompletedNCT00704535Results posted
• Ezetimibe Reverse Cholesterol Transport (RCT) Pilot StudyCompletedNCT00701727Phase 4Results posted
• An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-HypercholesterolemiaCompletedNCT00694109Phase 3Results posted
• Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in HypercholesterolemiaCompletedNCT00690443Phase 2Results posted
• A Study of MK-6213 Co-Administered With Atorvastatin in Participants With Hypercholesterolemia (MK-6213-006)CompletedNCT00687271Phase 2Results posted
• Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With HypercholesterolemiaCompletedNCT00683618Phase 3Results posted
• Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED)CompletedNCT00654628Phase 4Results posted
• Coadministration of Ezetimibe and Atorvastatin in Patients With Primary Hypercholesterolemia (P05456)CompletedNCT00654095Phase 3Results posted
• Coadministration of Ezetimibe and Simvastatin in Patients With Primary Hypercholesterolemia (P05457)CompletedNCT00653523Phase 3Results posted
• Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)CompletedNCT00652327Phase 4Results posted
• Safety of Red Yeast Rice for High Cholesterol in Individuals With Statin IntoleranceCompletedNCT00639223Phase 2Results posted
• Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic PatientsCompletedNCT00631189Phase 4Results posted
• Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial HypercholesterolemiaCompletedNCT00607373Phase 3Results posted
• Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.CompletedNCT00570739Phase 3Results posted
• The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's DiseaseTerminatedNCT00548145Not applicableResults posted
• Effect of MK0524A on Cholesterol Levels (0524A-048)CompletedNCT00536510Phase 3Results posted
• A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)CompletedNCT00535405Phase 3Results posted
• A Randomized Study To Evaluate Efficacy And Safety Of A Fixed Combination Therapy Of Amlodipine And AtorvastatinCompletedNCT00530946Phase 3Results posted
• (H.E.L.P.)Apheresis Therapy to Compare the Reduction of LDL (Low Density Lipoprotein) CholesterolCompletedNCT00526058Not applicableResults posted
• 12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With EzetimibeCompletedNCT00525824Phase 3Results posted
• Effect of Policosanol as Monotherapy and Adjunctive to Statin TherapyCompletedNCT00510809Not applicableResults posted
• A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)CompletedNCT00496730Phase 3Results posted
• MK-0524B Lipid Study (MK-0524B-063)CompletedNCT00479882Phase 3Results posted
• A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)CompletedNCT00479713Phase 3Results posted
• Study of Extended Release Niacin/Laropiprant on Lipids (0524A-067)CompletedNCT00479388Phase 3Results posted
• Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial HypercholesterolemiaCompletedNCT00477594Phase 2Results posted
• AEGR-733 and Atorvastatin 20 mg vs. Monotherapy in Moderate HypercholesterolemiaCompletedNCT00474240Phase 2Results posted
• A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With DyslipidemiaCompletedNCT00463606Phase 3Results posted
• A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)CompletedNCT00462748Phase 3Results posted
• Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)CompletedNCT00442897Phase 4Results posted
• Improving the Quality of Patient Care by Using a Clinical Expert System.CompletedNCT00430755Not applicableResults posted
• Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mgTerminatedNCT00427960Phase 4Results posted
• The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED)CompletedNCT00423579Phase 4Results posted
• Ezetimibe and Simvastatin in Primary Hypercholesterolemia, Diabetes Mellitus Type 2, and Coronary Heart Disease (COMPLETED)CompletedNCT00423488Phase 3Results posted
• Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)CompletedNCT00418834Phase 3Results posted
• Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)CompletedNCT00413972Phase 3Results posted
• Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)CompletedNCT00409773Phase 3Results posted
• Caduet vs Usual Care in Subjects With Hypertension and Additional Risk FactorsCompletedNCT00407537Phase 4Results posted
• The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate HypercholesterolemiaCompletedNCT00405067Phase 2Results posted
• Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED)TerminatedNCT00384293Phase 3Results posted
• Measure Liver Fat Content After ISIS 301012 (Mipomersen) AdministrationCompletedNCT00362180Phase 2Results posted
• PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatinCompletedNCT00355615Phase 3Results posted
• Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk FactorsCompletedNCT00344175Phase 3Results posted
• Study of Pitavastatin in Elderly Patients With Primary Hypercholesterolemia or Combined DyslipidemiaCompletedNCT00330876Phase 3Results posted
• Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart DiseaseCompletedNCT00329160Phase 4Results posted
• Long-Term Extension Study of Pitavastatin in Patients With Primary Hypercholesterolemia or Combined DyslipidemiaCompletedNCT00325780Phase 3Results posted
• Intensive Glycemic Control and Skeletal Health StudyCompletedNCT00324350Phase 3Results posted
• A Patient-Spouse Intervention for Self-Managing High CholesterolCompletedNCT00321789Not applicableResults posted
• Adding Ezetimibe Tablet to Ongoing Treatment With Atorvastatin in Subjects With High Cholesterol and Multiple Coronary Heart Disease Risk Factors (Study P04060)(COMPLETED)CompletedNCT00319449Phase 4Results posted
• Study to Compare the Efficacy and Safety of Pitavastatin and SimvastatinCompletedNCT00309777Phase 3Results posted
• Study to Compare the Efficacy and Safety of Pitavastatin and SimvastatinCompletedNCT00309738Phase 3Results posted
• To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090)CompletedNCT00276484Phase 3Results posted
• To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 mg (0653-079)(COMPLETED)CompletedNCT00276458Phase 3Results posted
• To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)CompletedNCT00271817Phase 3Results posted
• Study to Compare the Efficacy and Safety of Pitavastatin and Pravastatin in Elderly PatientsCompletedNCT00257686Phase 3Results posted
• Study to Compare the Efficacy of Pitavastatin With That of Atorvastatin in Lowering Cholesterol LevelsCompletedNCT00249249Phase 3Results posted
• A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid ReductionCompletedNCT00203476Phase 4Results posted
• IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)CompletedNCT00202878Phase 3Results posted
• Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)CompletedNCT00166504Phase 4Results posted
• Effect of Statins on Oxidative Stress and Endothelial Progenitor CellsCompletedNCT00166036Phase 2Results posted
• Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High CholesterolCompletedNCT00145574Phase 4Results posted
• Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)CompletedNCT00129402Phase 3Results posted
• Clinical Trial of Protein and Blood PressureCompletedNCT00107744Not applicableResults posted
• The Effects of Metformin on Blood Vessel Structure and FunctionCompletedNCT00105066Phase 2Results posted
• A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)CompletedNCT00101439Phase 3Results posted
• Action to Control Cardiovascular Risk in Diabetes (ACCORD)CompletedNCT00000620Phase 3Results posted
• Long-Term Cardiovascular Impact of ArmoLIPID Cholesterol Plus: An In Silico Study Using Digital TwinsCompletedNCT07892092
• The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African AmericansCompletedNCT07833384Early Phase 1
• Therapeutic Effects of Cinnamon-Enriched Cookies on Hypercholesterolemia and Liver FunctionCompletedNCT07740473Not applicable
• Alleviation of Hypercholesterolemia Through Newly Developed Cookies Supplementedwithpumpkin (Cucurbita Pepo L.) Seeds and Walnuts (Juglans Regia L.) Among Arthrosclerosispatients.CompletedNCT07737067Not applicable

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