Hepatitis E clinical trials
The registry lists 37 studies for Hepatitis E across more than 10 countries. 9 are recruiting or about to start. 32 of them are mainly about Hepatitis E (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Xiamen Innovax Biotech Co., Ltd (7) · Xiamen University (3) · International Vaccine Institute (2) · Mahmoud Abdel Rahman (1) · Combined Military Hospital, Pakistan (1) · Norwegian Institute of Public Health (1) · Hospices Civils de Lyon (1) · Carmel Medical Center (1)
What is being tested here
Drugs under test in Hepatitis E studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ursodeoxycholic Acid | 1 | 0 | 1 |
| Escherichia coli | 0 | 0 | 6 |
| Hecolin | 0 | 1 | 3 |
| Sofosbuvir | 0 | 0 | 1 |
| Ribavirin | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Dec 2026Study of AT-587 in Healthy Subjects · Atea Pharmaceuticals, Inc.
Who these studies take
Of the 7 Hepatitis E studies recruiting now, 1 (14%) set no upper age limit and 5 (71%) stop at 75 or younger. 4 (57%) take children under 18. 1 (14%) are for women only and 0 (0%) for men only; 5 (71%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (43%) | 3 (43%) |
| 18 | 6 (86%) | 5 (71%) |
| 30 | 6 (86%) | 5 (71%) |
| 40 | 7 (100%) | 6 (86%) |
| 50 | 5 (71%) | 5 (71%) |
| 65 | 5 (71%) | 5 (71%) |
| 75 | 3 (43%) | 3 (43%) |
| 85 | 1 (14%) | 1 (14%) |
Across all 37 studies, recruiting or not: 41% stop at 75 or younger and 32% at 65; 41% take children; 11% are for women only and 0% for men only; 57% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 37 of 37. search them.
- Study of AT-587 in Healthy SubjectsRecruitingNCT07728487Phase 11 country
- Comparative Evaluation of Oral Ursodeoxycholic Acid in Reducing Bilirubin Levels Among Patients With Acute Viral HepatitisNot yet recruitingNCT07525401Not applicable
- Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health PerspectiveRecruitingNCT073589101 country
- Immunogenicity and Safety of Hecolin® in HIV Positive/Negative Adults and in ChildrenRecruitingNCT06306196Phase 21 country
- Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne DiseasesNot yet recruitingNCT06859619Not applicable1 country
- Safety and Immunogenicity of Hecolin® in Healthy Pregnant WomenRecruitingNCT05808166Phase 21 country
- Molecular Characteristics and Prevalence of Viral Hepatitis E in Human Tissue and Cell DonorsRecruitingNCT06457438Not applicable1 country
- Exposure to Hepatitis E Virus in Occitania, FranceRecruitingNCT061373131 country
- Long-term Effectiveness of a Recombinant Hepatitis E VaccineRecruitingNCT059765941 country
- Seroprevalence of Hepatitis E in People With an Organ TransplantCompletedNCT021902531 country
- Prevalence of Hepatitis E During Follow-up Liver and Kidney Transplant Patients in Guadeloupe, French West IndiesCompletedNCT07729202Not applicable1 country
- Seroprevalence of Leptospirosis in Val Müstair, SwitzerlandCompletedNCT053004251 country
- Safety and Immunogenicity Study of Thiomersal-free Hepatitis E Vaccine in People Ages 16 Years and AboveCompletedNCT06564116Phase 41 country
- Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh.CompletedNCT02759991Phase 41 country
- Immunogenicity and Safety of Co-immunization With Cecolin and HecolinStatus unknownNCT05415345Phase 41 country
- Field Trial of Maternal Influenza Immunization in AsiaCompletedNCT01034254Phase 31 country
- Safety Study of Hepatitis E Vaccine (HEV239)CompletedNCT03827395Phase 11 country
- Morbidity and Mortality of Hepatitis E Virus Infections in BelgiumCompletedNCT04670419
- Epidemiological Study of Hepatitis E Virus in Maintenance Hemodialysis PatientsCompletedNCT02645955
- Clinical Trial of Recombinant Hepatitis E VaccineCompletedNCT01014845Phase 31 country
- A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial)CompletedNCT03365921Phase 41 country
- Seroprevalence Hepatitis E Infection in Healthy Blood DonorsCompletedNCT036012211 country
- A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )CompletedNCT02964910Phase 41 country
- A Safety and Efficacy Study of the Hepatitis E Vaccine in Nepal.CompletedNCT00287469Phase 21 country
- Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection.TerminatedNCT02558114Phase 41 country
- HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE)CompletedNCT03282474Phase 21 country
- A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule)CompletedNCT03168412Phase 41 country
- Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®)CompletedNCT02189603Phase 41 country
- HEV in Patients With Acute Non-A, Non-B, Non-C Hepatitis in Al-Rajhy University Hospital for LiverStatus unknownNCT03488589
- Hepatitis E Infection : Emergence Mechanisms in North-Eastern France of Polymorphic Clinical Forms.Status unknownNCT035240141 country
- Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb)CompletedNCT028475071 country
- A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine)CompletedNCT02584543Phase 41 country
- Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence StudyStatus unknownNCT02809885Not applicable1 country
- A Clinical Trial to Evaluate a Recombinant Hepatitis E Vaccine in Healthy AdultsCompletedNCT02603055Phase 11 country
- The Epidemiology of Hepatitis E Virus Infection in Israel and Potential Risk FactorsStatus unknownNCT02419625Not applicable
- A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)CompletedNCT02417597Phase 41 country
- Host Responses in Kidney-transplant Recipients With Chronic Hepatitis E Virus InfectionCompletedNCT01090232Not applicable1 country