Glioblastoma: all 1,951 studies

Page 9 of 20. Open to participants first (457), then studies with results posted, then the rest; newest registration first within each.

• Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or GliosarcomaCompletedNCT00335764Phase 1/2Results posted
• Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent GlioblastomaCompletedNCT00329719Phase 1/2Results posted
• Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma MultiformeCompletedNCT00323115Phase 2Results posted
• Motexafin Gadolinium, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or GliosarcomaCompletedNCT00305864Phase 1/2Results posted
• Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or GliosarcomaCompletedNCT00304031Phase 3Results posted
• Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic AstrocytomaCompletedNCT00301418Phase 1/2Results posted
• Efficacy and Safety of Imatinib Mesylate Plus Hydroxyurea (HU) in Patients With Recurrent Glioblastoma Multiforme (GBM)TerminatedNCT00290771Phase 2Results posted
• Radiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diagnosed GBMCompletedNCT00262730Phase 2Results posted
• Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma MultiformeCompletedNCT00253448Phase 2Results posted
• Dietary, Herbal and Alternative Medicine in Glioblastoma MultiformeTerminatedNCT00243022Phase 2Results posted
• Vorinostat in Treating Patients With Progressive or Recurrent Glioblastoma MultiformeCompletedNCT00238303Phase 2Results posted
• Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/GlioblastomaCompletedNCT00200161Phase 2Results posted
• Safety and Efficacy Study of Tarceva, Temodar, and Radiation Therapy in Patients With Newly Diagnosed Brain TumorsCompletedNCT00187486Phase 2Results posted
• Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive GlioblastomaCompletedNCT00154375Phase 3Results posted
• Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma MultiformeTerminatedNCT00112866Phase 2Results posted
• Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant GliomaCompletedNCT00112736Phase 1/2Results posted
• Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma MultiformeCompletedNCT00112502Phase 2Results posted
• Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed GliomasCompletedNCT00100802Phase 2Results posted
• Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System TumorsCompletedNCT00095940Phase 1/2Results posted
• Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor)CompletedNCT00093964Phase 2Results posted
• Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate CancerCompletedNCT00085566Phase 1/2Results posted
• FR901228 in Treating Patients With Recurrent High-Grade GliomasCompletedNCT00085540Phase 1/2Results posted
• Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeCompletedNCT00085254Phase 1/2Results posted
• Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RTTerminatedNCT00068770Phase 2Results posted
• Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeTerminatedNCT00052715Phase 2Results posted
• Phase I/II Evaluation of Temozolomide and ZARNESTRA (R115777) for Recurrent and Progressive Glioblastoma MultiformeCompletedNCT00050986Phase 1/2Results posted
• A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade GliomasCompletedNCT00045708Phase 1/2Results posted
• Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive MeningiomaCompletedNCT00045110Phase 1/2Results posted
• Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed GliomasCompletedNCT00042991Phase 1/2Results posted
• Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Glioblastoma MultiformeTerminatedNCT00006916Phase 2Results posted
• Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBMCompletedNCT00004146Phase 2Results posted
• Antineoplaston Therapy in Treating Adults With Residual/Recurrent/Progressive Glioblastoma MultiformeCompletedNCT00003474Phase 2Results posted
• Antineoplaston Therapy in Treating Patients With Newly-diagnosed Glioblastoma MultiformeCompletedNCT00003456Phase 2Results posted
• Microsurgical Resection Combined With Photodynamic Therapy for Recurrent GlioblastomaActive, not recruitingNCT07832448Not applicable
• Assessment of a Large US EHR Database as Meeting FDA Fit-for-Purpose Requirements to Provide External Controls for Study BPM31510 in Participants With GlioblastomaActive, not recruitingNCT07674095
• GliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4CompletedNCT07673679
• The Clinical Application Value of SPECT Imaging Targeting LRRC15 in Malignant TumorsCompletedNCT07651020
• SM-1 Combined With Temozolomide in Subjects With Refractory or Recurrent High-Grade GliomasCompletedNCT07635173Phase 1
• Administration of Repurposed Ketoconazole in Glioma PatientsActive, not recruitingNCT07585851Early Phase 1
• Dietary Cysteine and Methionine Deprivation (CMD) in Glioma PatientsWithdrawnNCT07553520Not applicable
• Use of Fluorescence in GliomasCompletedNCT07499141
• A Phase I Study to Evaluate the Safety and Tolerability of JL15003 Injection in Patients With Recurrent GlioblastomaCompletedNCT07497373Phase 1
• Comprehensive Analysis of Chemotherapy and Targeted Therapy Outcomes in Recurrent Malignant GliomasActive, not recruitingNCT07448480
• Clinical Significance of Liquid Biopsy in Brain Tumor Patients: a 5-ALA Guided ApproachActive, not recruitingNCT07420543
• Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBMActive, not recruitingNCT07209241Phase 1
• PriCoTTF Study: TTFields Before and During Radiotherapy for Newly Diagnosed GlioblastomaCompletedNCT07120620Phase 1/2
• A Study to Test a New Fluid to Improve the Quality of Images Obtained by Using Sound Waves (Ultrasound) During SurgeryActive, not recruitingNCT07042620Not applicable
• Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade GliomaActive, not recruitingNCT07031765Phase 1
• CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial RadiotherapyActive, not recruitingNCT06973096Phase 1
• Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma PatientsWithdrawnNCT06964815Not applicable
• Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)SuspendedNCT06806228Phase 1
• Development and Implementation of an Intervention Enhancing Involvement of Relatives to Patients With Acquired Brain Injury or Malignant Brain TumourCompletedNCT06796335
• Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)CompletedNCT06665724Phase 1
• Phase 1 Open-label Study of 123I-ATT001 in Subjects With Relapsed GlioblastomaCompletedNCT06650605Phase 1
• 5G-EMERALD: Amivantamab in Malignant Brain TumoursActive, not recruitingNCT06632236Phase 1
• Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral ChemotherapyCompletedNCT06625047Phase 4
• A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant GliomaActive, not recruitingNCT06614855Phase 1
• Correlation Between Prostate-specific Membrane Antigen Positron Emission Tomography and Arterial Spin Labeling Perfusion Imaging in GlioblastomaCompletedNCT06600399
• Clinical Study on the Safety and Efficacy of Novel Oncolytic Virus in the Treatment of Recurrent Malignant GliomaCompletedNCT06562621Phase 1/2
• Therapeutic Support to Strengthen Dignity, Mental Well-being and Quality of Life in Acute Palliative Care Patients.CompletedNCT06549075Not applicable
• A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With CancerActive, not recruitingNCT06521567Phase 1/2
• A Study of Bicalutamide With Brain Re-irradiation to Treat Recurrent/Progressive High Grade GliomaWithdrawnNCT06501911Phase 1
• Expectations and Needs of a Glioblastoma CaregiverCompletedNCT06490497
• Magnetic Resonance Fingerprinting Guided Extended Resection in GlioblastomasWithdrawnNCT06455189Phase 1
• FET-PET/MRI Based Treatment Planning for Glioblastoma Multiforme in Post-Surgical Patients (FET-TREAT)CompletedNCT06451042
• CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot TrialCompletedNCT06439420Phase 2
• RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)Active, not recruitingNCT06389591Phase 1
• A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated GlioblastomaActive, not recruitingNCT06388733Phase 3
• Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT PromoterTerminatedNCT06359379Phase 2
• Tumor Treating Fields for Newly Diagnosed Glioblastoma: Two Emulated Trials With Chinese Multi-Hospital Based Real-World DataCompletedNCT06346821
• A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or RecurrenceActive, not recruitingNCT06336291Phase 2
• Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)SuspendedNCT06329570Phase 1/2
• Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent GlioblastomaWithdrawnNCT06328036Phase 2
• Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent GlioblastomaSuspendedNCT06325683Phase 2
• T Cells and Pembrolizumab for Recurrent and Newly Diagnosed GlioblastomaActive, not recruitingNCT06157541Phase 1/2
• Glioblastoma Remote Monitoring and Care - Research ProtocolSuspendedNCT06129760Not applicable
• Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade GliomaActive, not recruitingNCT06108206
• A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).Active, not recruitingNCT06105619Phase 2/3
• A Clinical Trial on Combined (Neo-)Adjuvant Intravenous Plus Intracranial Administration of Ipilimumab and Nivolumab in Recurrent GlioblastomaActive, not recruitingNCT06097975Phase 1
• Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM PatientsCompletedNCT06095375Phase 1
• N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive GlioblastomaActive, not recruitingNCT06061809Phase 2
• Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM PatientsActive, not recruitingNCT06054529
• Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)TerminatedNCT06038760
• Glioblastoma Psychosocial Support ProgramCompletedNCT06038604Not applicable
• Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and BevacizumabActive, not recruitingNCT06011109Phase 1/2
• Azeliragon in MGMT Unmethylated GlioblastomaActive, not recruitingNCT05986851Phase 2
• Repurposed Drugs in Research for Cancer Clinical Trials- PitavastatinCompletedNCT05977738Early Phase 1
• A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.TerminatedNCT05977322Phase 1
• Lenvatinib, Pembrolizumab, and Tumor Treating Fields (TTFields) for Second-line Treatment of GlioblastomaWithdrawnNCT05973903Phase 1/2
• Physiological MRI for Precision Radiotherapy IDH-wildtype GlioblastomaActive, not recruitingNCT05970757Not applicable
• Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or AstrocytomaCompletedNCT05938387Phase 1
• TVI-Brain-1 in Expanded Access PatientNo longer availableNCT05936216
• Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain TumorsTerminatedNCT05934630
• Genetic Testing of Cerebrospinal Fluid to Diagnose and Monitor GlioblastomaWithdrawnNCT05927610Not applicable
• Post-operative Adjuvant Therapy w/wo GammaTile + Systemic TherapyWithdrawnNCT05900908Phase 4
• Predictive Values of Preoperative [68Ga]Ga-PSMA-11 PET/CT in Patients With Suspected Brain Tumours of Glial OriginCompletedNCT05896449Not applicable
• Randomized Study of Neo-adjuvant and Adjuvant Pembrolizumab With and Without Targeted Blood Brain Barrier Opening Using Exablate MRI-guided Focused Ultrasound (Exablate MRgFUS) for Recurrent GlioblastomaWithdrawnNCT05879120Phase 2
• Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma SurgeryCompletedNCT05873946
• Protective VEGF Inhibition for Isotoxic Dose Escalation in GlioblastomaActive, not recruitingNCT05871021Phase 2
• Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed GlioblastomaActive, not recruitingNCT05864534Phase 2

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