Geographic Atrophy: all 188 studies
Page 1 of 2. Open to participants first (52), then studies with results posted, then the rest; newest registration first within each.
- A Clinical Trial to Evaluate the Efficacy and Safety of Bevemipretide Ophthalmic Topical Solution in Subjects Who Have Dry Age-Related Macular Degeneration (Dry AMD)Not yet recruitingNCT07927010Phase 2/3
- A Study to Assess the Efficacy and Safety of RO7965032 in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationRecruitingNCT07851259Phase 2
- An Open-label Extension Study of the Long-Term Safety of Vonaprument (ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)Not yet recruitingNCT07807969Phase 3
- Adaptive Optics Scanning Light Ophthalmoscopy (AOSLO) and Microperimetry (MP) Sub-studyEnrolling by invitationNCT07747662Not applicable
- An Open-label Safety, Tolerability and Exploratory Efficacy Clinical Trial of PST-611 in Geographic AtrophyNot yet recruitingNCT07705568Phase 2
- A Study to Evaluate the Safety and Effect of TO-O-1007 Intravitreal Implant in Subjects With Geographic AtrophyRecruitingNCT07668804Phase 1/2
- A Study in Adults With Geographic AtrophyRecruitingNCT07606365Phase 2
- Safety and Efficacy Study of Novel Gene Therapy AGX-08 for Geographic AtrophyNot yet recruitingNCT07602127Early Phase 1
- Phase 1 Study of C.001 in Retinal DegenerationRecruitingNCT07594236Phase 1
- Lesion-tailored, Fundus-controlled Perimetry in Geographic Atrophy (GA).RecruitingNCT07582042
- Pterygopalatine Ganglion Stimulation for the Treatment of Geographic AtrophyNot yet recruitingNCT07570355Not applicable
- Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot StudyRecruitingNCT07556406
- Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic AtrophyRecruitingNCT07531927Not applicable
- Real-time Acoustic Biofeedback for Enhancing Fixation Stability: A Proof-of-concept Study to Improve Ophthalmic Imaging Diagnostic QualityEnrolling by invitationNCT07529041Not applicable
- A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular DegenerationRecruitingNCT07441642Phase 2
- Validation of Virtual Reality Tests for the Assessment of Patients With Age-related Macular Degeneration as Clinical EndpointsNot yet recruitingNCT07433088Not applicable
- Study in Human iPSCs-derived RPE Cells Transplantation for Advanced (Late-stage) AMDRecruitingNCT07418177Phase 1/2
- An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)RecruitingNCT07392255Phase 1/2
- Wide Field OCTA in Ocular DiseasesNot yet recruitingNCT07298174
- Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult ParticipantsRecruitingNCT07230834Phase 1
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular DegeneratioRecruitingNCT07215390Phase 2
- A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular DegenerationRecruitingNCT07215234Phase 1/2
- SGLT2 Inhibitors in Geographic AtrophyRecruitingNCT07174687Phase 2
- Microperimetry Changes in Retinal Function in Macular DisordersEnrolling by invitationNCT07170683
- Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationRecruitingNCT07160179Phase 1/2
- A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMDRecruitingNCT07158775Phase 1/2
- A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)RecruitingNCT07144137
- A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular DegenerationRecruitingNCT07029945Phase 1/2
- Phase 2 Study of ADX-038 in Participants With Geographic AtrophyRecruitingNCT06990269Phase 2
- A Prospective Observational Study to Assess the Reliability and Validity of the MLSDTRecruitingNCT06805474
- A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular DegenerationRecruitingNCT06765980Phase 1/2
- Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular DegenerationRecruitingNCT06662162Not applicable
- A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMDRecruitingNCT06659549Phase 2
- Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMDRecruitingNCT06659445Phase 2
- A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)RecruitingNCT06635148Phase 2/3
- A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)RecruitingNCT06557460Phase 2
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic AtrophyRecruitingNCT06541704Phase 3
- Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.RecruitingNCT06394232Phase 1/2
- Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease ProgressionRecruitingNCT06351657
- Progression of Early Atrophic LesionsRecruitingNCT05959005
- A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251RecruitingNCT05626114Phase 2
- ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent StudyEnrolling by invitationNCT05481827Phase 2
- Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMDRecruitingNCT05438732Not applicable
- Observation of the Natural Course of Age-related Macular DegenerationNot yet recruitingNCT05418231
- Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular DegenerationRecruitingNCT04847635Not applicable
- Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its ProgressionRecruitingNCT04739319
- Non Exudative AMD Imaged With SS-OCT- ExtensionRecruitingNCT04469140
- Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular DegenerationRecruitingNCT04339764Phase 1/2
- Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot StudyRecruitingNCT03921931Not applicable
- A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular DegenerationRecruitingNCT03178149Phase 1
- Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable
- High Resolution Retinal ImagingRecruitingNCT01866371
- Retinal Fundus Flavoprotein Fluorescence in Age Related Macular DegenerationCompletedNCT06381596Not applicableResults posted
- COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Geographic AtrophyCompletedNCT05961332Not applicableResults posted
- Patients With Geographic Atrophy and Their Patient Journey in the United States (US)CompletedNCT05891275Results posted
- Avacincaptad Pegol Open-Label Extension for Patients With Geographic AtrophyCompletedNCT05536297Phase 3Results posted
- Study to Evaluate the Safety and Effectiveness of Intravitreal Injections (IVI) of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD)CompletedNCT05269966Phase 4Results posted
- A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationTerminatedNCT05019521Phase 2Results posted
- Study of Innovative Multimodal Imaging Biomarkers to Predict Anatomical Outcome in Naive Patients With wAMD Treated With Brolucizumab.CompletedNCT04774926Phase 4Results posted
- An Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan (APL-2) in Subjects With Geographic Atrophy Secondary to AMDCompletedNCT04770545Phase 3Results posted
- Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular DegenerationCompletedNCT04679935Phase 4Results posted
- A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic AtrophyCompletedNCT04656561Phase 2Results posted
- A Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationTerminatedNCT04607148Phase 2Results posted
- An Extension Study Assessing the Efficacy and Safety of Brolucizumab in a Treat-to-Control Regimen in Patients With Neovascular Age-related Macular Degeneration Who Have Completed the CRTH258A2303 (TALON) StudyCompletedNCT04597632Phase 3Results posted
- HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005TerminatedNCT04566445Phase 2Results posted
- A Study of NGM621 in Participants With Geographic AtrophyCompletedNCT04465955Phase 2Results posted
- EXPLORE: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005TerminatedNCT04437368Phase 2Results posted
- A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)CompletedNCT04435366Phase 3Results posted
- Study of Brolucizumab in Adult Patients With Suboptimal Anatomically Controlled Neovascular Age-related Macular DegenerationCompletedNCT04264819Phase 3Results posted
- Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)CompletedNCT04005352Phase 3Results posted
- A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)TerminatedNCT03972709Phase 2Results posted
- Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular EdemaCompletedNCT03927690Phase 2Results posted
- FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMDTerminatedNCT03846193Phase 1/2Results posted
- Phase 2/3 Study of ALK-001 in Geographic AtrophyCompletedNCT03845582Phase 2/3Results posted
- A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationCompletedNCT03525613Phase 3Results posted
- Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationCompletedNCT03525600Phase 3Results posted
- Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMDCompletedNCT02800356Not applicableResults posted
- Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)TerminatedNCT02745119Phase 3Results posted
- Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular DegenerationCompletedNCT02686658Phase 2/3Results posted
- Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMDCompletedNCT02684578Phase 2Results posted
- A Study to Evaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic AtrophyCompletedNCT02659098Phase 2Results posted
- CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic Atrophy (GA)CompletedNCT02515942Phase 2Results posted
- Study of Pegcetacoplan (APL-2) Therapy in Patients With Geographic AtrophyCompletedNCT02503332Phase 2Results posted
- A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic AtrophyCompletedNCT02288559Phase 2Results posted
- A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationTerminatedNCT02247531Phase 3Results posted
- A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular DegenerationTerminatedNCT02247479Phase 3Results posted
- Safety and Efficacy of Switching From Aflibercept to Ranibizumab in Patients With nAMDCompletedNCT02161575Phase 4Results posted
- A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD PatientsCompletedNCT02130024Phase 4Results posted
- A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular DegenerationTerminatedNCT02087085Phase 2Results posted
- Pharmacokinetics of CLG561 in Patients With Advanced Age-Related Macular DegenerationCompletedNCT01835015Phase 1Results posted
- Efficacy and Safety of Ranibizumab 0.5 mg Administered as Two Alternative Dosing Regimens in Chinese Patients With nAMD (Age Related Macular Degeneration)CompletedNCT01775124Phase 4Results posted
- Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLOCompletedNCT01692938Results posted
- A Multicenter, Proof-Of-Concept Study Of Intravitreal AL-78898A In Patients With Geographic Atrophy (GA) Associated With Age-Related Macular Degeneration (AMD)TerminatedNCT01603043Phase 2Results posted
- An Extension Study to Evaluate the Long-Term Safety of Lampalizumab in Participants With Geographic AtrophyTerminatedNCT01602120Phase 2Results posted
- Efficacy, Safety And Tolerability Study Of RN6G In Subjects With Geographic Atrophy Secondary to Age-related Macular DegenerationTerminatedNCT01577381Phase 2Results posted
- Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)CompletedNCT01527500Phase 2Results posted
- Sirolimus for Advanced Age-Related Macular DegenerationCompletedNCT01445548Phase 1/2Results posted
- Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular DegenerationCompletedNCT01342926Phase 2Results posted
- Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE)CompletedNCT01272076Results posted
- Complement Inhibition With Eculizumab for the Treatment of Non-Exudative Macular Degeneration (AMD)CompletedNCT00935883Phase 2Results posted