Fractures, Ununited clinical trials
The registry lists 43 studies for Fractures, Ununited across more than 10 countries. 10 are recruiting or about to start. 23 of them are mainly about Fractures, Ununited (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Pseudarthrosis too: 79 studies, 15 open.
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Who runs them
Zimmer Biomet (3) · Emdadi Kamyab Hospital (2) · Charite University, Berlin, Germany (2) · LifeNet Health (1) · University Hospital, Basel, Switzerland (1) · Methodist Health System (1) · Qinghai University (1) · Orthopaedie Zentrum Zuerich (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Sep 2027PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation · Phase 3 · Major Extremity Trauma Research Consortium
Who these studies take
Of the 6 Fractures, Ununited studies recruiting now, 5 (83%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (17%) | 1 (17%) |
| 18 | 5 (83%) | 5 (83%) |
| 30 | 6 (100%) | 6 (100%) |
| 40 | 6 (100%) | 6 (100%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 5 (83%) | 5 (83%) |
Across all 43 studies, recruiting or not: 28% stop at 75 or younger and 21% at 65; 12% take children; 2% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Local Iloprost Therapy to Promote Bone Healing in High Risk FracturesNov 9, 2026NCT07924722
Studies
Recruiting first, then most recently updated. Showing 43 of 43. search them.
- Local Iloprost Therapy to Promote Bone Healing in High Risk FracturesNot yet recruitingNCT07924722Phase 2
- Allograft vs. Autograft NonunionNot yet recruitingNCT07310082Not applicable1 country
- Exactech Proximal Humerus Fracture Plate System Post Market Clinical Follow-upRecruitingNCT057039581 country
- Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture CareRecruitingNCT042990221 country
- PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After FixationRecruitingNCT05699174Phase 31 country
- G7 Freedom Constrained Vivacit-E LinersEnrolling by invitationNCT05587244Not applicable1 country
- Tuebingen Register of Union Failure After Fractures of the Upper and Lower ExtremitiesRecruitingNCT060981571 country
- Prospective Validation Study of the CD8+TEMRA Cells As a Prognostic Biomarker of Healing Outcome After FractureRecruitingNCT066583791 country
- Intramedullary Bone Grafting for Open Tibial Shaft FracturesRecruitingNCT03891888Not applicable1 country
- Treatment of Nonunion Fractures With Mesenchymal Stromal Cells (MSCs)Enrolling by invitationNCT06103396Phase 1/21 country
- Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal SystemActive, not recruitingNCT07628010Not applicable1 country
- Relationships Between Vitamin D and Orthopedic TraumaCompletedNCT045646251 country
- Using the Boneflo System During Orthopedic and Trauma Surgery: A Prospective Multicenter StudyCompletedNCT07562165Not applicable1 country
- Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening SystemTerminatedNCT064007321 country
- Validity of the Non-union Scoring System in Management of Long Bone Fracture Non-unionCompletedNCT07207447Not applicable1 country
- Impact of Time Interval Between Trauma and Operation on Clinical Outcome in Patients With Delayed Rib Fixation (Nonunion)Active, not recruitingNCT067880671 country
- Union Rate of Scaphoid Non-Union Fracture in Adults by Herbert Screw Versus Volar Buttress PlateCompletedNCT07039695Not applicable1 country
- G7 BiSpherical Acetabular Shell PMCF StudyActive, not recruitingNCT032668744 countries
- Distal Targeter vs Free-handCompletedNCT05613257Not applicable1 country
- A Comparative Study of 2 Doses of BM Autologous H-MSC+Biomaterial vs Iliac Crest AutoGraft for Bone Healing in Non-UnionCompletedNCT03325504Phase 34 countries
- Distal Femur Fracture Nonunion - Statistical Analysis PlanCompletedNCT051637951 country
- Antibiotic Loaded Calcium Sulfate RCTTerminatedNCT03875963Not applicable1 country
- Adipose Tissue Derived Stromal Vascular Fraction (SVF) Application in Treatment of Long Bones NonunionCompletedNCT04340284Phase 1/21 country
- Scaphoid Non-union and Low-intensity Pulsed Ultrasound TrialStatus unknownNCT02383160Not applicable1 country
- Ankle Arthrodesis Nail for 2-level Pathologic Tibial FractureStatus unknownNCT04940754Not applicable1 country
- Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic OsteomyelitisStatus unknownNCT04945434Not applicable
- Treatment of Atrophic Nonunion Fractures by Autologous Mesenchymal Stem Cell Percutaneous GraftingWithdrawnNCT01429012Phase 21 country
- Feasibility Study of Aastrom Tissue Repair Cells to Treat Non-Union Fractures.TerminatedNCT00424567Phase 1/21 country
- Mesenchymal Stromal Cells for the Treatment of Non-union Fractures of Long BonesCompletedNCT02230514Phase 1/21 country
- Comparative Study of Gene-activated Bone Substitute and Autobone in Treatment of Long Bone NonunionsStatus unknownNCT047058571 country
- Results of the Staged Surgical Approach for Management of Infected Un-united Femoral Shaft Fractures in AdultsStatus unknownNCT04681846
- Reamer Irrigator Aspirator (RIA) vs Autogenous Iliac Crest Bone Graft (AICBG) for the Treatment of Non-unionsStatus unknownNCT01382485Not applicable1 country
- NGS for Non-unionsStatus unknownNCT039373101 country
- Smoking Cessation in Nonunion, Malunion, Osseous InfectionWithdrawnNCT007542991 country
- A Clinical Registry to Collect Patient Outcome Date for the BIOMET® Stimulator SystemsTerminatedNCT017508401 country
- Treatment of Nonunion of Limb Fracture With Human Amniotic Epithelial Cells(hAECs)Status unknownNCT03031509Phase 1/21 country
- Platelet-rich Plasma Combined With Conventional Surgery in the Treatment of Atrophic Nonunion of Femoral Shaft FracturesStatus unknownNCT03129971Not applicable
- Autologous BM-MSC Transplantation in Combination With Platelet Lysate (PL) for Nonunion TreatmentStatus unknownNCT02448849Phase 2/31 country
- Evaluation of the Risk for Radiographic and Clinical Nonunion in Patients With Previous Bisphosphonates Therapy.WithdrawnNCT017315351 country
- Allogenic Mesenchymal Stem Cell for Bone Defect or Non Union FractureStatus unknownNCT02307435Early Phase 11 country
- The Efficacy of Mesenchymal Stem Cells for Stimulate the Union in Treatment of Non-united Tibial and Femoral Fractures in Shahid Kamyab HospitalCompletedNCT01788059Phase 21 country
- Evaluation the Treatment of Nonunion of Long Bone Fracture of Lower Extremities (Femur and Tibia) Using Mononuclear Stem Cells From the Iliac Wing Within a 3-D Tissue Engineered ScaffoldStatus unknownNCT01958502Phase 21 country
- Treatment of Atrophic Nonunion by Preosteoblast CellsCompletedNCT00916981Phase 1/21 country