Essential Hypertension: all 538 studies

Page 2 of 6. Open to participants first (76), then studies with results posted, then the rest; newest registration first within each.

• Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Elderly Patients With Essential HypertensionCompletedNCT01615198Phase 3Results posted
• Efficacy and Safety of LCZ696 in Comparison to Olmesartan in Japanese Patients With Essential HypertensionCompletedNCT01599104Phase 3Results posted
• Perindopril Amlodipine for the Treatment of HypertensionCompletedNCT01556997Phase 3Results posted
• A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil AloneCompletedNCT01456169Phase 3Results posted
• MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352)CompletedNCT01307046Phase 3Results posted
• A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351)CompletedNCT01307033Phase 3Results posted
• MK-0954E Study in Participants With Hypertension (MK-0954E-357)CompletedNCT01302691Phase 3Results posted
• MK-0954E Phase III Long-Term Study in Participants With Hypertension (MK-0954E-356)CompletedNCT01299376Phase 3Results posted
• A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential HypertensionCompletedNCT01256411Phase 2Results posted
• A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential HypertensionCompletedNCT01251146Phase 4Results posted
• Efficacy and Safety of SPA100 (Fixed-dose Combination of Aliskiren/Amlodipine) in Patients With Essential HypertensionCompletedNCT01237223Phase 3Results posted
• Efficacy and Safety of LCZ696 Compared to Placebo in Patients With Essential HypertensionCompletedNCT01193101Phase 2Results posted
• Effectiveness and Patient Self-assessed Compliance of Blood Pressure Treatment With Tarka® Fixed Combination in Patients With Essential HypertensionCompletedNCT01127139Results posted
• Hybrid Blood Pressure Monitor ValidationCompletedNCT01120990Phase 4Results posted
• Efficacy of Aliskiren Compared to Ramipril in the Treatment of Moderate Systolic Hypertensive PatientsCompletedNCT01042392Phase 4Results posted
• Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.CompletedNCT01033071Phase 3Results posted
• Efficacy and Safety of Valsartan/Amlodipine in Patients With Mild to Moderate Essential HypertensionCompletedNCT01001572Phase 3Results posted
• Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential HypertensionCompletedNCT00996281Phase 3Results posted
• Parallel-Group Comparison of Olmesartan (OLM), Amlodipine (AML) and Hydrochlorothiazid (HCTZ) in HypertensionCompletedNCT00923091Phase 3Results posted
• A Therapeutic Exploratory Clinical Study to Evaluate the Antihypertensive Efficacy of Fimasartan (BR-A-657•K) During 24 Hours in Patients With Mild to Moderate Essential HypertensionCompletedNCT00922441Phase 2Results posted
• Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in HypertensionCompletedNCT00902538Phase 3Results posted
• Efficacy and Safety of Olmesartan Medoxomil in Stage 1 and 2 Essential HypertensionCompletedNCT00890591Phase 4Results posted
• Calcium Channel Blockers (CCBs) or Diuretics as an Add-on to Olmesartan Medoxomil in HypertensionCompletedNCT00858702Phase 4Results posted
• Olmesartan Medoxomil Versus Losartan in Patients With HypertensionCompletedNCT00857285Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe HypertensionCompletedNCT00846365Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe HypertensionCompletedNCT00818883Phase 3Results posted
• Efficacy and Tolerability of an Aliskiren-based Treatment Algorithm in Patients With Mild to Moderate HypertensionCompletedNCT00765947Phase 4Results posted
• Efficacy and Safety Study of Azilsartan Medoxomil Compared to Ramipril for Treating Essential HypertensionCompletedNCT00760214Phase 3Results posted
• A Study to Evaluate Efficacy and Safety of LCI699 in Participants With Essential HypertensionCompletedNCT00758524Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Aliskiren Alone and in Combination With Amlodipine in Essential HypertensionCompletedNCT00739973Phase 3Results posted
• Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled StudyCompletedNCT00706134Phase 3Results posted
• Safety, Tolerability, and Efficacy of Once Daily Amlodipine/Valsartan 5/80 as Compared to Amlodipine/Valsartan 5/40 or to Amlodipine 5 mg Monotherapy in Patients 65 Years of Age and Older With Essential HypertensionCompletedNCT00699192Phase 3Results posted
• An Efficacy and Safety Study of Azilsartan Medoxomil Compared to Valsartan and Olmesartan in Participants With Essential Hypertension.CompletedNCT00696436Phase 3Results posted
• A Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential HypertensionCompletedNCT00696384Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil in Participants With Essential HypertensionCompletedNCT00696241Phase 3Results posted
• One-Year Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential HypertensionCompletedNCT00695955Phase 3Results posted
• Effect of the Fixed Dose Combination Amlodipine/Valsartan on Central Aortic Blood Pressure in Uncontrolled Essential Hypertension With Amlodipine 5 mgCompletedNCT00687973Phase 4Results posted
• A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential HypertensionCompletedNCT00667719Phase 3Results posted
• Efficacy and Safety of Once Daily Dosing of Aliskiren (300 mg (qd) Once a Day) to Twice Daily Dosing of Aliskiren (150 mg (Bid) Twice a Day) in Treating Moderate Hypertension.CompletedNCT00654875Phase 4Results posted
• A Study Evaluating the Gastrointestinal (GI) Safety and Tolerability of Aliskiren Compared to Ramipril in Essential HypertensionCompletedNCT00631917Phase 4Results posted
• Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood PressureCompletedNCT00624065Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential HypertensionCompletedNCT00591773Phase 3Results posted
• Efficacy and Safety Comparison of Azilsartan Medoxomil to Valsartan in Participants With Essential HypertensionCompletedNCT00591578Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil, Once Daily (QD), Co-Administered With Amlodipine in Participants With Essential HypertensionCompletedNCT00591266Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil in African American Participants With Essential HypertensionCompletedNCT00591253Phase 3Results posted
• Efficacy and Safety of LCZ696A in Patients With Essential HypertensionCompletedNCT00549770Phase 2Results posted
• Olmesartan/HCTZ 40/12.5 mg Combination Therapy Versus Olmesartan Medoxomil 40 mg Monotherapy in Essential HypertensionCompletedNCT00441350Phase 3Results posted
• Efficacy and Safety of Valsartan/Amlodipine Compared to Amlodipine in Patients With Essential HypertensionCompletedNCT00437645Phase 3Results posted
• Combination of Olmesartan and Hydrochlorothiazide in Essential HypertensionCompletedNCT00430950Phase 3Results posted
• Use of the Combination of Olmesartan and Hydrochlorothiazide in Essential HypertensionCompletedNCT00430508Phase 3Results posted
• Efficacy and Safety of Valsartan and Amlodipine in Patients With Essential HypertensionCompletedNCT00425373Phase 2/3Results posted
• Olmesartan and an add-on Treatment in Patients With Mild to Moderate HypertensionCompletedNCT00311155Phase 4Results posted
• Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential HypertensionCompletedNCT00219141Phase 3Results posted
• Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control Their Blood Pressure in Primary Care Clinics in Germany and PakistanCompletedNCT07878728Not applicable
• Monitoring the Effectiveness and Safety of Antihypertensive Therapy With a Fixed-Dose Combination of Perindopril and Amlodipine in Patients With Uncontrolled Essential HypertensionActive, not recruitingNCT07876895
• Circadian Disruption And Cardiovascular Risk In Young Adults With HypertensionActive, not recruitingNCT07770958
• Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Sacubitril/AllisartanCompletedNCT07704697Phase 3
• Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With AmlodipineCompletedNCT07704684Phase 3
• A Phase II Clinical Study of QR12000 Compound Tablets in Patients With Moderate to Severe Essential HypertensionCompletedNCT07700875Phase 2
• Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High CholesterolCompletedNCT07564726Phase 3
• Nifedipine Extended-Release in Patients With Mild or Moderate HypertensionCompletedNCT07448506Phase 3
• Mat Pilates With Paced Breathing Versus Diaphragmatic Breathing in Stage II HypertensionCompletedNCT07433790Not applicable
• Aerobic Exercise vs Physiological Ischemic Training in Stage 2 HypertensionCompletedNCT07375407Not applicable
• Safety and Pharmacokinetics Study of BCD101 in Healthy VolunteersCompletedNCT07282145Phase 1
• The Use of Virtual Reality and Music Therapy for Hypertensive UrgencyCompletedNCT07272486Not applicable
• Sleep Hygiene Education and Blood Pressure Control in Essential Hypertension in Primary CareCompletedNCT07257237Not applicable
• A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential HypertensionCompletedNCT07116863Phase 3
• A Study to Evaluate the Pharmacokinetic, Pharmacodynamic Characteristics and the Safety After Administration by Doses of BR1400-1, BR1400-2, BR1400-3 in Healthy Adult VolunteersCompletedNCT06889064Phase 1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1018 and Coadministration of BR1018A and BR1018B in Healthy Adult VolunteersCompletedNCT06889012Phase 1
• A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227BCompletedNCT06884085Phase 1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fed ConditionsCompletedNCT06744439Phase 1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fasting ConditionsCompletedNCT06744426Phase 1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 Under Fasting ConditionsCompletedNCT06744127Phase 1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 in Healthy Volunteers Fed ConditionsCompletedNCT06744062Phase 1
• Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With HyperuricemiaCompletedNCT06718062Phase 4
• Efficacy and Safety of DWC202404 and DWC202314 in Patients With HypertensionCompletedNCT06682000Phase 3
• A Phase III Study to Efficacy and Safety of DWC202405/DWC202313 and DWC202314 in Patients With HypertensionCompletedNCT06671392Phase 3
• Positive Care Effect of the Digital Health Assistant ADELE Blood Pressure for Hypertension PatientsCompletedNCT06663280Not applicable
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1019" and Co-administration of "BR1019-3" and "BR1019-2" in Healthy VolunteersCompletedNCT06636877Phase 1
• Effectiveness of Entresto (Sacubitril/Valsartan) in Japanese Patients With HypertensionCompletedNCT06604897
• Prescribing Patterns of Antihypertensive Drugs in Uncomplicated HypertensionCompletedNCT06517134
• Study of SGB-3908 in Healthy Subjects and Mildly Hypertensive SubjectsCompletedNCT06501586Phase 1
• To Assess Allisartan Isoproxil/Sustained-Release Indapamide in Patients With Essential Hypertension Uncontrolled With Allisartan IsoproxilCompletedNCT06500689Phase 3
• The Plasma Metabolomics Profiling of Primary AldosteronismCompletedNCT06500000
• Health Expenses and Outcomes of the DASH Diet in Egyptian Patients With HypertensionCompletedNCT06499194Not applicable
• To Assess Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine or Allisartan IsoproxilCompletedNCT06465264Phase 3
• Food is Medicine vs Lifestyle Medicine For Cardiovascular Kidney Metabolic (CKM) SyndromeCompletedNCT06461273Not applicable
• Phase 3 Study to Evaluate the Efficacy and Safety of Co-administrated AD-2021 and AD-2022CompletedNCT06448962Phase 3
• A Study to Evaluate Efficacy and Safety of HCP1803 Compared to RLD2001-1 in Patients with Essential HypertensionCompletedNCT06438172Phase 3
• Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory CapacityCompletedNCT06418074Not applicable
• Efficacy and Safety of AJU-C52 in Essential Hypertension PatientsCompletedNCT06416865Phase 3
• Effects of Valsartan vs Amlodipine and Low BP on Kidney Outcomes in Essential HypertensionCompletedNCT06395194Phase 3
• Left Atrial Enlargement: A Crucial Indicator for Identifying Atrial Fibrillation in Patients With HypertensionCompletedNCT06359873
• Functional Inspiratory Muscle Training in Patients Diagnosed With HypertensionCompletedNCT06343246Not applicable
• A Study to Evaluate the Efficacy and Safety of AD-224CompletedNCT06291207Phase 3
• Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.CompletedNCT06287580Early Phase 1
• Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients with Essential HypertensionActive, not recruitingNCT06282549
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1019" and Co-administration of "BR1019-1" and "BR1019-2"CompletedNCT06226727Phase 1
• Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential HypertensionCompletedNCT06212648Phase 2
• Safety, Tolerability, PK and PD of ADX-850 in Participants With HypertensionActive, not recruitingNCT06205628Phase 1

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