Epidermolysis Bullosa Dystrophica: all 78 studies

Page 1 of 1. Open to participants first (21), then studies with results posted, then the rest; newest registration first within each.

• A Pilot Multicentric Open Study Assessing the Efficacy and Safety of NEMOlizumab in Patients ≥ 12yo With Dystrophic Epidermolysis BullosaNot yet recruitingNCT07926867Phase 2/3
• A Study to Evaluate ENERGI-F703EB Cream in Epidermolysis BullosaRecruitingNCT07858422Phase 2
• Phase 4 Master Protocol for Patients Prescribed Prademagene Zamikeracel for the Treatment of WoundsNot yet recruitingNCT07717736Phase 4
• A Long-Term Safety Follow-up Registry for Patients Who Received Treatment With Prademagene Zamikeracel for Recessive Dystrophic Epidermolysis Bullosa (RDEB) in the Post-Marketing SettingRecruitingNCT07700966
• Treatment of Dysphagia in Patients With Dystrophic Epidermolysis Bullosa With Budesonide: a Retrospective Bicentric Study Nice - Paris St Louis / Necker (EBUDE Study)Not yet recruitingNCT07684105Not applicable
• Effect of Ev.FV on Wound Healing in Dystrophic Epidermolysis BullosaRecruitingNCT07230223Phase 1/2
• GMEB-SASS: A Gene-Modified Skin Substitute for RDEB TreatmentRecruitingNCT07193134Phase 1/2
• A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis BullosaRecruitingNCT07016750Phase 3
• Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)Not yet recruitingNCT07011589Phase 1/2
• A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis BullosaRecruitingNCT06917690Phase 3
• Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis BullosaRecruitingNCT06834035Phase 1/2
• A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-studyRecruitingNCT06594393Phase 2
• A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)RecruitingNCT06563414
• A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving FilsuvezRecruitingNCT06423573
• Study of the Blood and Skin Immunological Profile of Patients With Recessive Dystrophic Epidermolysis Bullosa: in Vivo Analysis and the Impact of Placental Stem Cells in VitroRecruitingNCT06177353
• CACIPLIQ20 in Wound Healing in Subjects With Epidermolysis BullosaRecruitingNCT06007235Not applicable
• Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis BullosaRecruitingNCT05157958Phase 2
• Long-Term Follow-up ProtocolRecruitingNCT04917887
• MSC EVs in Dystrophic Epidermolysis BullosaRecruitingNCT04173650Phase 1/2
• Computational Drug Repurposing for All EBS CasesRecruitingNCT03269474
• Characteristics of Patients With Recessive Dystrophic Epidermolysis BullosaRecruitingNCT01019148
• A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB PatientsCompletedNCT05944250Not applicableResults posted
• Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEBCompletedNCT04491604Phase 3Results posted
• A Study of FCX-007 for Recessive Dystrophic Epidermolysis BullosaActive, not recruitingNCT04213261Phase 3Results posted
• A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB PatientsCompletedNCT03536143Phase 1/2Results posted
• To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB)CompletedNCT03472287Phase 1Results posted
• Gentamicin for RDEBCompletedNCT03012191Phase 1/2Results posted
• A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa (RDEB)TerminatedNCT02810951Phase 1/2Results posted
• Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation PatientsCompletedNCT02698735Phase 1/2Results posted
• Treatment of Chronic and Non-Chronic Wounds in Patients With Recessive Dystrophic Epidermolysis Bullosa Using Helicoll Collagen Dressings Versus Standard of CareCompletedNCT01716169Not applicableResults posted
• Efficacy of Granulocyte Colony Stimulating Factor (GCSF) In Patients With Dystrophic Epidermolysis BullosaCompletedNCT01538862Phase 2Results posted
• Gene Transfer for Recessive Dystrophic Epidermolysis BullosaCompletedNCT01263379Phase 1/2Results posted
• Safety and Efficacy of Apligraf in Nonhealing Wounds of Subjects With Junctional or Dystrophic Epidermolysis Bullosa (EB)TerminatedNCT00587223Phase 3Results posted
• Allogeneic Hematopoietic Stem Cell Transplant For Epidermolysis BullosaTerminatedNCT00478244Not applicableResults posted
• Curcumin-Based Photodynamic Therapy in Epidermolysis Bullosa: Wound Healing, Quality of Life, and Salivary BiomarkersActive, not recruitingNCT07596927Phase 4
• Evaluation of D-Fi for the Treatment of Wounds Due to DEBActive, not recruitingNCT06892639Phase 3
• Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis BullosaActive, not recruitingNCT06713434Phase 1
• Artificial Intelligence Patient App for RDEB SCCsActive, not recruitingNCT05843994
• A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated PatientsActive, not recruitingNCT05725018Phase 3
• Study of PTW-002 in Patients With Dominant or Recessive Dystrophic Epidermolysis Bullosa Due to Mutation(s) in Exon 73 of the COL7A1 GeneStatus unknownNCT05529134Phase 1/2
• Growth Hormone in EBStatus unknownNCT05390073
• Extension Study to PTR-01-002 (A Study in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Patients Previously Treated With PTR-01)CompletedNCT05143190Phase 2
• The State of Sexual Development in Children With Inherited Epidermolysis BullosaStatus unknownNCT05033574
• A Long-term Treatment With B-VEC for Dystrophic Epidermolysis BullosaCompletedNCT04917874Phase 3
• INM-755 (Cannabinol) Cream for Treatment of Epidermolysis BullosaCompletedNCT04908215Phase 2
• Gynecological Follow-up of Patients With Dystrophic Epidermolysis Bullosa (EBD)CompletedNCT04757727
• A Study of PTR-01 in Recessive Dystrophic Epidermolysis BullosaCompletedNCT04599881Phase 2
• Safety and Effectiveness Study of Allogeneic Umbilical Cord Blood-derived Mesenchymal Stem Cell in Patients With RDEBCompletedNCT04520022Phase 1/2
• Molecular Signatures of Cutaneous Squamous Cell Carcinoma During Recessive Dystrophic Epidermolysis BullosaStatus unknownNCT04285294
• Phase 3, Open-label Clinical Trial of EB-101 for the Treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB)CompletedNCT04227106Phase 3
• The Natural History of Wounds in Patients With Dystrophic Epidermolysis Bullosa (DEB)WithdrawnNCT04214002
• A Pilot Study to Explore the Role of Gut Flora in Epidermolysis BullosaWithdrawnNCT04213703
• Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent GraftsActive, not recruitingNCT04186650Phase 1/2
• Rigosertib in Patients With Recessive Dystrophic Epidermolysis Bullosa Associated SCCCompletedNCT04177498Early Phase 1
• Self-Assembled Skin Substitute for the Treatment of Epidermolysis BullosaActive, not recruitingNCT04171661Early Phase 1
• Safety Study and Preliminary Efficacy of Infusion Haploidentical Mesenchymal Stem Cells Derived From Bone Marrow for Treating Recessive Dystrophic Epidermolysis BullosaStatus unknownNCT04153630Phase 1/2
• Rigosertib for RDEB-SCCCompletedNCT03786237Phase 1/2
• A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)CompletedNCT03752905Phase 1/2
• A Double-blind, Randomized, Intra-subject Placebo-controlled, Multicenter, Multiple Dose Study, Evaluating Safety, Proof of Mechanism, Preliminary Efficacy and Systemic Exposure in Subjects With Confirmed DDEB or RDEB Diagnosis With One or More Pathogenic Mutations in Exon 73 in the COL7A1 GeneTerminatedNCT03605069Phase 1/2
• Evaluation of the Safety and Efficacy Study of RGN-137 Topical Gel for Junctional and Dystrophic Epidermolysis BullosaTerminatedNCT03578029Phase 2
• Allogeneic ABCB5-positive Stem Cells for Treatment of Epidermolysis BullosaCompletedNCT03529877Phase 1/2
• Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)Status unknownNCT03392909Phase 1/2
• Proof of Concept Study for a Dressing GloveCompletedNCT03241628
• A Follow-up Study to Evaluate the Efficacy and Safety of ALLO-ASC-DFU in ALLO-ASC-EB-101 Clinical TrialCompletedNCT03183934
• Clinical Trial to Assess Safety and Efficacy of Autologous Cultured Epidermal Grafts Containing Epidermal Stem Cells Genetically Modified in Patients With RDEB.TerminatedNCT02984085Phase 1/2
• Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Dystrophic Epidermolysis BullosaCompletedNCT02579369Phase 1/2
• Safety Study of Gene-modified Autologous Fibroblasts in Recessive Dystrophic Epidermolysis BullosaCompletedNCT02493816Phase 1
• Mesenchymal Stromal Cells in Adults With Recessive Dystrophic Epidermolysis BullosaStatus unknownNCT02323789Phase 1/2
• A Comparative Study of the Healing of Chronic Ulcers of Recessive Epidermolysis Bullosa : Dressing vs Amniotic MembraneStatus unknownNCT02286427Phase 3
• Short Term Observational Study in DEB PatientsCompletedNCT02178969
• Pilot Study Evaluating the Efficiency and the Tolerance of the PDT in the Treatment of Epidermal Dysplasia for Patients Affected by Hereditary DEBWithdrawnNCT02004600Not applicable
• Study of Immune Tolerance and Capacity for Wound Healing of Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)CompletedNCT01874769
• Prospective, Longitudinal Natural History Study in Dystrophic Epidermolysis BullosaWithdrawnNCT01768026
• A Pilot Study of HP802-247 in Dystrophic Epidermolysis BullosaWithdrawnNCT01528306Phase 2
• Treatment of Epidermolysis Bullosa Dystrophica by Polyphenon E (Epigallocatechin 3 Gallate)CompletedNCT00951964Phase 2
• Characteristics of Adult Patients With Recessive Dystrophic Epidermolysis BullosaCompletedNCT00904163
• Allogeneic Stem Cell Transplantation (ALLOSCT) in Recessive Dystrophic Epidermolysis Bullosa (RDEB)TerminatedNCT00881556Early Phase 1
• Recessive Dystrophic Epidermolysis Bullosa Screening for Possible Gene TransferTerminatedNCT00533572

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