Carcinoma in Situ clinical trials
The registry lists 78 studies for Carcinoma in Situ across more than 10 countries. 22 are recruiting or about to start. 20 of them are mainly about Carcinoma in Situ (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 2 narrower conditions too, such as Carcinoma, Intraductal, Noninfiltrating: 461 studies, 92 open.
Get an email when these change. Save the Carcinoma in Situ studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Protara Therapeutics (4) · CG Oncology, Inc. (3) · M.D. Anderson Cancer Center (3) · National Cancer Institute (NCI) (2) · Fidia Farmaceutici s.p.a. (2) · Bioniche Life Sciences Inc. (2) · Children's Oncology Group (2) · Bayer (2)
What is being tested here
Drugs under test in Carcinoma in Situ studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Deeper Intubation Make Effects on Cervical Esophageal ESD · Fujian Provincial Hospital
- Jan 2027EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- May 2027A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia · Elizabeth J Franzmann
- Aug 2027Performance of Multi-Cancer Detection Test in Asymptomatic Patients With Neoplastic Lesions · Sun Yat-sen University
- Oct 2027Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study · First Affiliated Hospital of Wenzhou Medical University
- Nov 2027VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer · Olgun Elicin
Who these studies take
Of the 18 Carcinoma in Situ studies recruiting now, 11 (61%) set no upper age limit and 4 (22%) stop at 75 or younger. 2 (11%) take children under 18. 3 (17%) are for women only and 0 (0%) for men only; 1 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (11%) | 2 (11%) |
| 18 | 17 (94%) | 15 (83%) |
| 30 | 17 (94%) | 14 (78%) |
| 40 | 17 (94%) | 14 (78%) |
| 50 | 17 (94%) | 14 (78%) |
| 65 | 15 (83%) | 14 (78%) |
| 75 | 15 (83%) | 14 (78%) |
| 85 | 13 (72%) | 12 (67%) |
Across all 78 studies, recruiting or not: 19% stop at 75 or younger and 15% at 65; 9% take children; 21% are for women only and 0% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 78. Browse all 78 → or search them.
- A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder CancerRecruitingNCT06545955Phase 38 countries
- Performance of Multi-Cancer Detection Test in Asymptomatic Patients With Neoplastic LesionsNot yet recruitingNCT07915271
- Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder CancerRecruitingNCT07480356Phase 32 countries
- A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)RecruitingNCT06833073Phase 219 countries
- Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 StudyNot yet recruitingNCT07189793Phase 21 country
- Project: Every Child for Younger Patients With CancerRecruitingNCT024022446 countries
- Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder CancerRecruitingNCT05951179Phase 27 countries
- InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for CancerRecruitingNCT054637961 country
- LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-NaïveRecruitingNCT04752722Phase 1/210 countries
- Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-GuerinRecruitingNCT07283835Phase 21 country
- Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBCRecruitingNCT07322263Phase 21 country
- Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral LesionsNot yet recruitingNCT06876038Phase 21 country
- EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast CancerRecruitingNCT06115486Not applicable1 country
- A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral DysplasiaRecruitingNCT05865028Phase 21 country
- A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.RecruitingNCT06022029Phase 12 countries
- VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx CancerRecruitingNCT04057209Not applicable3 countries
- NWRD09 for HPV-16 Related Intraepithelial Neoplasia and Cervical CancerRecruitingNCT07092007Not applicable1 country
- Effectiveness of Cervical Screening in Unvaccinated, Herd Effect Protected Women (HPV400)Enrolling by invitationNCT04755517Not applicable1 country
- NWRD09 for HPV-16 Positive and HPV-16 Related Intraepithelial Neoplasia and Cervical Cancer Patients.RecruitingNCT06741150Not applicable1 country
- Deeper Intubation Make Effects on Cervical Esophageal ESDRecruitingNCT06420258Phase 41 country
- Comparison of pCLE and EB in Gastric Lesion DiagnosisRecruitingNCT06389448Not applicable1 country
- Fuzheng Nizeng Formula for Chronic Atrophic Gastritis With Low-grade Intraepithelial Neoplasia, a Multicenter Randomized Controlled TrialRecruitingNCT06324825Not applicable1 country
- Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)CompletedNCT03258593Phase 11 country
- A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)TerminatedNCT05014139Phase 16 countries
- PDT Plus Vitamin D3 for Anal DysplasiaWithdrawnNCT02698293Phase 11 country
- Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With CancerCompletedNCT03223753Phase 32 countries
- Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-GuerinActive, not recruitingNCT04452591Phase 36 countries
- Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)Active, not recruitingNCT05024773Phase 36 countries
- Therapeutic Nipple Sparing Mastectomy.CompletedNCT02311959Phase 31 country
- Handheld Ultrasound Device to Triage Women With a Positive Clinical Breast Examination by Trained Non-radiologistsCompletedNCT06056843Not applicable1 country
- E7 TCR T Cells for Human Papillomavirus-Associated CancersCompletedNCT02858310Phase 1/21 country
- Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in KenyaCompletedNCT06263582Phase 11 country
- Skin Fluorescent Imaging (SFI) System in Patients With NeviCompletedNCT043682471 country
- Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology PracticesCompletedNCT03808818Not applicable1 country
- Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1a)CompletedNCT05085977Phase 14 countries
- Safety and Toxicity Study of Intravesical Instillation of TARA-002 in Adults with High-grade Non-muscle Invasive Bladder Cancer (Phase 1b)CompletedNCT05085990Phase 11 country
- Role of MRI Breast in Detection of Ductal Carcinoma in SituActive, not recruitingNCT067441401 country
- Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-GuerinCompletedNCT04387461Phase 22 countries
- A Study of ALT-801 in Patients With Bacillus Calmette-Guerin (BCG) Failure Non-Muscle Invasive Bladder CancerTerminatedNCT01625260Phase 1/21 country
- Evaluation of Potential Predictors of Adherence by Investigating a Representative Cohort of Multiple Sclerosis (MS) Patients in Germany Treated With BetaferonCompletedNCT024866401 country
- Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck CancerCompletedNCT03268993Not applicable1 country
- Evaluation of in Vitro Devices on Self-collected Vaginal Swab and Urine Sample for Testing of Human Papilloma VirusCompletedNCT043127373 countries
- Lavage of the Uterine Cavity for the Diagnosis of Serous Tubal Intraepithelial CarcinomaCompletedNCT02039388Not applicable8 countries
- Early Detection of High Grade Ovarian Cancer Using Uterine Lavage EHUD Study and Duplex SequencingCompletedNCT04823871Not applicable4 countries
- Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the BladderTerminatedNCT02901548Phase 21 country
- Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell CancerCompletedNCT03182959Early Phase 11 country
- Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder CancerTerminatedNCT01438112Phase 2/31 country
- Study of ONCOFID-P-B™ (PACLITAXEL-HYALURONIC ACID)CompletedNCT04798703Phase 12 countries
- A Study of Stimulator of Interferon Genes (STING) Agonist E7766 in Non-muscle Invasive Bladder Cancer (NMIBC) Including Participants Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy, INPUT-102WithdrawnNCT04109092Phase 11 country
- Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)TerminatedNCT03333694Phase 13 countries