Astrocytoma: all 434 studies

Page 2 of 5. Open to participants first (79), then studies with results posted, then the rest; newest registration first within each.

• First in Patient Study for PF-06840003 in Malignant GliomasTerminatedNCT02764151Phase 1Results posted
• Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG TumorsCompletedNCT02684058Phase 2Results posted
• Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001CompletedNCT02655601Phase 1/2Results posted
• Nivolumab With DC Vaccines for Recurrent Brain TumorsCompletedNCT02529072Phase 1Results posted
• Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma MultiformeCompletedNCT02465268Phase 2Results posted
• Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain TumorsTerminatedNCT02372409Phase 2Results posted
• DC Migration Study for Newly-Diagnosed GBMCompletedNCT02366728Phase 2Results posted
• Pegylated Interferon ALFA-2b in Children With Juvenile Pilocytic Astrocytomas and Optic Pathway GliomasCompletedNCT02343224Phase 2Results posted
• Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System TumorsTerminatedNCT02255461Phase 1Results posted
• Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade GliomasActive, not recruitingNCT02192359Phase 1Results posted
• Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade GliomasCompletedNCT02186509Phase 1Results posted
• 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent GliomasTerminatedNCT02175745Not applicableResults posted
• Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade GliomaTerminatedNCT02168270Phase 1Results posted
• Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant GliomaActive, not recruitingNCT02062827Phase 1Results posted
• Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade GliomaTerminatedNCT02039778Not applicableResults posted
• Everolimus With and Without Temozolomide in Adult Low Grade GliomaTerminatedNCT02023905Phase 2Results posted
• Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade GliomasCompletedNCT02015819Phase 1Results posted
• Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine GliomasCompletedNCT01922076Phase 1Results posted
• Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22TerminatedNCT01884740Phase 1/2Results posted
• Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain TumorsTerminatedNCT01836549Phase 2Results posted
• Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant AstrocytomasTerminatedNCT01721577Phase 1/2Results posted
• Phase II NKTR-102 In Bevacizumab-Resistant High Grade GliomaCompletedNCT01663012Phase 2Results posted
• Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma MultiformeCompletedNCT01648348Phase 1/2Results posted
• Vaccine for Patients With Newly Diagnosed or Recurrent Low-Grade GliomaCompletedNCT01635283Phase 2Results posted
• Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway GliomaCompletedNCT01553149Phase 2Results posted
• Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine GliomasCompletedNCT01514201Phase 1/2Results posted
• Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent GliomasTerminatedNCT01478321Phase 2Results posted
• Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or EpendymomaCompletedNCT01462695Phase 2Results posted
• Safety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following BevacizumabCompletedNCT01403610Phase 2Results posted
• BIBF 1120 for Recurrent High-Grade GliomasCompletedNCT01380782Phase 2Results posted
• Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade AstrocytomasTerminatedNCT01338857Phase 2Results posted
• Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV GliomaCompletedNCT01290692Phase 2Results posted
• Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain IrradiationCompletedNCT01288235Phase 2Results posted
• Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade GliomaCompletedNCT01236560Phase 2/3Results posted
• A Study of PD 0332991 in Patients With Recurrent Rb Positive GlioblastomaTerminatedNCT01227434Phase 2Results posted
• Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine GliomaCompletedNCT01189266Phase 1/2Results posted
• RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant GliomaTerminatedNCT01189240Phase 1/2Results posted
• A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MBCompletedNCT01125800Phase 1/2Results posted
• Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade GliomaTerminatedNCT01095094Phase 2Results posted
• Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV GliomaCompletedNCT01081223Phase 1/2Results posted
• Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second RelapseTerminatedNCT01068782Phase 2Results posted
• Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant GliomaCompletedNCT01051557Phase 1/2Results posted
• A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent GlioblastomaTerminatedNCT01044966Phase 1/2Results posted
• External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade AstrocytomasCompletedNCT01012609Phase 2Results posted
• A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade GliomasCompletedNCT00995007Phase 2Results posted
• Dasatinib and Bevacizumab in Treating Patients With Recurrent or Progressive High-Grade Glioma or Glioblastoma MultiformeCompletedNCT00892177Phase 2Results posted
• Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine GliomaCompletedNCT00879437Phase 2Results posted
• Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic AstrocytomaCompletedNCT00841555Phase 1Results posted
• Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic GliomaCompletedNCT00823797Phase 2Results posted
• Everolimus in Treating Patients With Recurrent Low-Grade GliomaCompletedNCT00823459Phase 2Results posted
• Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)CompletedNCT00789828Phase 3Results posted
• Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade GliomasCompletedNCT00782626Phase 2Results posted
• Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary GlioblastomaTerminatedNCT00761280Phase 3Results posted
• Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)CompletedNCT00723827Results posted
• Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard TherapyCompletedNCT00679354Phase 2Results posted
• Tandutinib Plus Bevacizumab to Treat Recurrent Brain TumorsCompletedNCT00667394Phase 2Results posted
• A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and GlioblastomaCompletedNCT00606008Phase 2Results posted
• Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant GliomaCompletedNCT00589875Phase 2Results posted
• Efficacy of Protracted Temozolomide in Patients With Progressive High Grade GliomaCompletedNCT00575887Phase 2Results posted
• Sunitinib in Treating Patients With Recurrent Malignant GliomasCompletedNCT00499473Phase 2Results posted
• Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck CancerCompletedNCT00492089Phase 2Results posted
• Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis ComplexCompletedNCT00411619Phase 1/2Results posted
• The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601)CompletedNCT00392171Phase 2Results posted
• Viral Therapy in Treating Patients With Recurrent Glioblastoma MultiformeCompletedNCT00390299Phase 1Results posted
• Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade GliomaCompletedNCT00381797Phase 2Results posted
• VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to TemozolomideCompletedNCT00369590Phase 2Results posted
• Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and OligodendrogliomasTerminatedNCT00360828Phase 2Results posted
• Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic AstrocytomaCompletedNCT00301418Phase 1/2Results posted
• Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive GlioblastomaCompletedNCT00154375Phase 3Results posted
• Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant GliomaCompletedNCT00112736Phase 1/2Results posted
• Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed GliomasCompletedNCT00100802Phase 2Results posted
• Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System TumorsCompletedNCT00095940Phase 1/2Results posted
• FR901228 in Treating Patients With Recurrent High-Grade GliomasCompletedNCT00085540Phase 1/2Results posted
• A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade GliomasCompletedNCT00045708Phase 1/2Results posted
• Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive MeningiomaCompletedNCT00045110Phase 1/2Results posted
• Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed GliomasCompletedNCT00042991Phase 1/2Results posted
• Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed GliomasCompletedNCT00004259Phase 3Results posted
• Antineoplaston Therapy in Treating Adult Patients With Anaplastic AstrocytomaCompletedNCT00003537Phase 2Results posted
• Antineoplaston Therapy in Treating Patients With Low-Grade AstrocytomaTerminatedNCT00003471Phase 2Results posted
• Antineoplaston Therapy in Treating Patients With Anaplastic AstrocytomaCompletedNCT00003470Phase 2Results posted
• Antineoplaston Therapy in Treating Children With Low-Grade AstrocytomaCompletedNCT00003468Phase 2Results posted
• GliomaAI-Oligo: MRI-Based Detection of IDH Mutant OligodendrogliomaCompletedNCT07673705
• GliomaAI-Astro4: MRI-Based Detection of IDH Mutant Astrocytoma Grade 4CompletedNCT07673679
• GliomaAI-Astro23: MRI-Based Detection of IDH Mutant Astrocytoma (Grade 2 and 3)CompletedNCT07673666
• Comprehensive Analysis of Chemotherapy and Targeted Therapy Outcomes in Recurrent Malignant GliomasActive, not recruitingNCT07448480
• Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid TumorsTerminatedNCT07121829Phase 1
• Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade GliomaActive, not recruitingNCT07031765Phase 1
• Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT06894979Phase 1
• Whole-Brain Tumor Burden Metrics with Inflammatory and Molecular Markers to Predict Postoperative Neurocognitive Decline in GliomaCompletedNCT06885333
• Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)CompletedNCT06665724Phase 1
• Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral ChemotherapyCompletedNCT06625047Phase 4
• Impact of IDH Mutation and Adjuvant Chemo(radio)therapy on Survival Outcome in Grade II/III AstrocytomaCompletedNCT06620926
• A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant GliomaActive, not recruitingNCT06614855Phase 1
• CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot TrialCompletedNCT06439420Phase 2
• Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade GliomaActive, not recruitingNCT06108206
• Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain TumorsTerminatedNCT05934630
• Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade GliomasTerminatedNCT05737212Phase 1/2
• Vorasidenib Expanded Access ProgramApproved for marketingNCT05592743
• A Study of AB-218 in Patients With IDH1 Mutated Low Grade GliomaCompletedNCT05577416Early Phase 1
• Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade GliomaActive, not recruitingNCT05561374Phase 1

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